Results 51 to 60 of about 160,290 (294)

The data on the relationship between polymorphism of HTR1B and DBH genes and attention-deficit hyperactivity disorder in adults with or without substance use disorders

Data in Brief, 2018
There is a positive relationship between attention-deficit hyperactivity disorder and tendency toward drug use in numerous studies. The present study was aimed to investigate the relationship between polymorphism of serotonin receptor 1B gene (HTR1B) and
Mojgan Khademi, Katayoon Razjouian, Rozita Davari-Ashtiani, Fariba Arabgol, Firoozeh Jafari, Hosein Darvish   +5 more
doaj   +1 more source

Attention Deficit Hyperactivity Disorder and Genetics [PDF]

Psikiyatride Güncel Yaklaşımlar, 2018
Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder of which three basic symptoms are lack of attention, over-activity that is improper to the age and impulsivity, all of which appear in childhood.
Fatih Hilmi Cetin, Yasemen Isik
doaj   +1 more source

Palatable‐Food–Driven Top‐Down Circuit Inhibits PVNCRF Activity to Mitigate Stress Via Peri‐PVNCRFR1 Neurons

Advanced Science, EarlyView.
Palatable food alleviates stress and prevents anxiety. This study uncovers a dedicated neural pathway: dopamine release in the PFC activates D1R neurons, whose projections to the peri‐PVN engage a population of anxiolytic CRFR1 neurons. These neurons then inhibit stress‐induced hyperactivity of PVNCRF neurons, providing a circuit‐level explanation for ...
Yuchuan Hong, Shirui Jun, Tianjiao Deng, Gaojie Shao, Dan Liu, Yi Sun, Yan Chen, Qian Xiao, Jie Shao, Sheng Wang, Tianwen Huang, Fan Yang, Jie Tu   +12 more
wiley   +1 more source

Efficacy of lisdexamfetamine dimesylate throughout the day in children and adolescents with attention-deficit/hyperactivity disorder:results from a randomized, controlled trial [PDF]

, 2013
Lisdexamfetamine dimesylate (LDX) is a long-acting, prodrug stimulant therapy for patients with attention-deficit/hyperactivity disorder (ADHD). This randomized placebo-controlled trial of an optimized daily dose of LDX (30, 50 or 70 mg) was conducted in
Squires, Liza A., Bloomfield, Ralph, Dittmann R. W, Dittmann, RW, Coghill D. R, Squires, LA, Banaschewski, Tobias, Zuddas, Alessandro, Ralph Bloomfield, Coghill, David R, Lecendreux, Michel, Civil, R, Civil R, Civil, Richard, Squires L. A., Banaschewski T, Isabel Hernández Otero, Dittmann, Ralf W, Michel Lecendreux, Hernández Otero, Isabel, Squires, Liza A, Otero, IH, Alessandro Zuddas, Otero I. H, Lecendreux M, Coghill, DR, Tobias Banaschewski, David R. Coghill, Richard Civil, Banaschewski, T, Coghill, David R., Liza A. Squires, Otero, Isabel Hernández, Dittmann, Ralf W., Zuddas, A, Lecendreux, M, Bloomfield, R, Ralf W. Dittmann, Bloomfield R   +38 more
core   +1 more source

Heat Shock Protein 90: From Molecular Chaperone Function to Therapeutic Targeting in Malignancies

Advanced Science, EarlyView.
In this review, an integrated conceptual framework linking HSP90's molecular chaperone functions to its pathological roles in cancer is proposed. HSP90 serves as a central node that integrates oncogenic signaling, buffers proteotoxic stress, maintains cancer stem cell plasticity, and shapes tumor‐immune interactions, all of which converge to drive ...
Beibei Zhang, Xinxin Zou, Jiansong Zhou, Qinmiao Sun, Dahua Chen   +4 more
wiley   +1 more source

Genomic Contributors to Congenital Diaphragmatic Hernia: Results of Exome Sequencing in 560 Probands and Cross Reference of Findings in an Independent Cohort

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT There is a strong genetic contribution to the etiology of congenital diaphragmatic hernia (CDH). This study evaluated genetic testing results and diagnostic yield for fetuses and children with CDH. This was a retrospective cohort study of exome sequencing (ES) performed at GeneDx for fetuses and children ≤ 18 years of age with CDH compared ...
Justin Blair, Kevin Carratu, Natalie E. Rintoul, Holly L. Hedrick, William H. Peranteau, Catherine M. Avitabile, Kirsty McWalter, Paul Kruszka, Ian D. Krantz, K. Taylor Wild   +9 more
wiley   +1 more source

How teachers′ knowledge of attention deficit hyperactivity disorder makes difference in doctors′ diagnostic decisions and management?

Saudi Journal of Medicine and Medical Sciences, 2015
Objective: The teacher′s knowledge plays a key role in the process of assessing, screening, and diagnosing attention deficit hyperactivity disorder.
Mohamed S Khalil, Elham Jenahi
doaj   +1 more source

Functional analysis of ADHD in children using nonlinear features of EEG signals [PDF]

Journal of Integrative Neuroscience, 2018
Attention deficit hyperactivity disorder is a neurodevelopmental condition associated with varying levels of hyperactivity, inattention, and impulsivity.
Shiva Khoshnoud, Mohammad Ali Nazari, Mousa Shamsi
doaj   +1 more source

Are language production problems apparent in adults who no longer meet diagnostic criteria for attention-deficit/hyperactivity disorder?

, 2012
In this study, we examined sentence production in a sample of adults (N = 21) who had had attention-deficit/hyperactivity disorder (ADHD) as children, but as adults no longer met DSM-IV diagnostic criteria (APA, 2000).
Veld, Sean N., Sean N. Veld, Veld, Sean, Engelhardt, Paul, Fernanda Ferreira, Engelhardt, Paul E., Nigg, Joel T., Ferreira, Fernanda, Paul E. Engelhardt, Joel T. Nigg   +9 more
core   +1 more source

Phenotype Expansion of Malan Syndrome: New Cases and a Review of the Literature

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Malan syndrome is an ultra‐rare overgrowth syndrome caused by pathogenic variants or deletions in nuclear factor one X (NFIX) located at 19p13.2. Here, we report a comprehensive literature review and phenotyping of known patients with Malan syndrome and present a novel cohort of eight patients.
Alex F. Nisbet, Sylvie A. Adams, Zoe S. Katz, Christal G. Delagrammatikas, Kosuke Izumi, Winifred Sigal, Kim Ventarola, Elaine H. Zackai, Julia E. Reid, Grant T. Liu, Jennifer M. Kalish   +10 more
wiley   +1 more source