Results 71 to 80 of about 349,459 (384)

Inhibition of Phosphodiesterase 10A by MP‐10 Rescues Behavioral Deficits and Normalizes Microglial Morphology and Synaptic Pruning in A Mouse Model of FOXP1 Syndrome

open access: yesAdvanced Science, EarlyView.
We demonstrate that Foxp1± mice, modeling FOXP1 haploinsufficiency, exhibit behavioral deficits, striatal neuroinflammatory changes including altered microglial complexity and synaptic pruning, and markedly reduced Pde10a expression. Pde10a inhibition starting immediately after birth restores Foxp1± behavior, microglial morphology, and pruning ...
Henning Fröhlich   +8 more
wiley   +1 more source

Attention Deficit Hyperactivity Disorder and Genetics [PDF]

open access: yesPsikiyatride Güncel Yaklaşımlar, 2018
Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder of which three basic symptoms are lack of attention, over-activity that is improper to the age and impulsivity, all of which appear in childhood.
Fatih Hilmi Cetin, Yasemen Isik
doaj   +1 more source

Attention Deficit Hyperactivity Disorder : an overview [PDF]

open access: yes, 2014
Attention Deficit Hyperactivity Disorder (ADHD) is a neurobehavioural disorder found more commonly, but not exclusively, in school-age children. The hallmarks of the condition are inattention and hyperactivity/ impulsivity, which often go together ...
Galea, Christine   +2 more
core  

Treatment alternatives for Attention-Deficit/Hyperactivity Disorder (ADHD) [PDF]

open access: yes, 1999
Objective: To review alternate treatments (Tx) of Attention-Deficit/Hyperactivity Disorder (ADHD)—those other than psychoactive medication and behavioral/psychosocial Tx—for the November, 1998 National Institute of Health (NIH) Consensus Development ...
Arnold, L. Eugene
core   +1 more source

Igfbp2 Downregulation in PVT‐CeA Glutamatergic Circuits Drives Neonatal Anesthesia‐Induced Fear Memory Deficits

open access: yesAdvanced Science, EarlyView.
Repeated neonatal sevoflurane exposure impairs adolescent fear memory through Igfbp2 downregulation in paraventricular thalamus‐central amygdala glutamatergic projections. Restoring Igfbp2 or activating this circuit rescues memory deficits, neuronal excitability, and spine density, identifying a precise molecular target for preventing anesthesia ...
Weiming Zhao   +16 more
wiley   +1 more source

How teachers′ knowledge of attention deficit hyperactivity disorder makes difference in doctors′ diagnostic decisions and management?

open access: yesSaudi Journal of Medicine and Medical Sciences, 2015
Objective: The teacher′s knowledge plays a key role in the process of assessing, screening, and diagnosing attention deficit hyperactivity disorder.
Mohamed S Khalil, Elham Jenahi
doaj   +1 more source

Working Effectively with People with Attention Deficit/ Hyperactivity Disorder [PDF]

open access: yes, 2001
This brochure on People with Attention Deficit/Hyperactivity Disorder and the Americans with Disabilities Act (ADA) is one of a series on human resources practices and workplace accommodations for persons with disabilities edited by Susanne M.
Bruyere, Susanne M   +2 more
core   +1 more source

Integral intervention in a child with epilepsy and attention-deficit/hyperactivity disorder symptoms [PDF]

open access: yes, 2014
A lo largo de estos años la investigación científica ha estudiado la aparición de síntomas típicos del Trastorno de Déficit de Atención con Hiperactividad en niños con epilepsia y su nivel de prevalencia.
Alonso García, Idaira María   +2 more
core   +4 more sources

Emotion dysregulation in attention deficit hyperactivity disorder.

open access: yesAmerican Journal of Psychiatry, 2014
Although it has long been recognized that many individuals with attention deficit hyperactivity disorder (ADHD) also have difficulties with emotion regulation, no consensus has been reached on how to conceptualize this clinically challenging domain.
P. Shaw   +3 more
semanticscholar   +1 more source

Genetic Evidence Supporting a Role for Brain Region Volume and Functional Network Alterations in Major Depression

open access: yesAdvanced Science, EarlyView.
Genome‐wide analyses indicate that reduced ventral diencephalon and thalamus volumes, along with decreased functional connectivity within the triple network (DMN/CEN/SN), are uniquely associated with the risk of major depression (MD) onset, compared to other similar severe psychiatric disorders.
Ming‐Min Xu   +7 more
wiley   +1 more source

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