Results 71 to 80 of about 1,966,391 (262)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Attentional network efficiency in elite biathletes and cross-country skiers

Frontiers in Sports and Active Living
This study provides the first investigation of attentional network efficiency in elite winter endurance athletes, comparing biathletes and cross-country skiers.
Irina S. Polikanova, Irina S. Polikanova, Irina S. Polikanova, Kirill S. Smirnov, Kirill S. Smirnov, Olga V. Sysoeva, Olga V. Sysoeva   +6 more
doaj   +1 more source

Neural network setups for a precise detection of the many-body localization transition: finite-size scaling and limitations

, 2019
Determining phase diagrams and phase transitions semi-automatically using machine learning has received a lot of attention recently, with results in good agreement with more conventional approaches in most cases.
Alet, Fabien, Théveniaut, Hugo
core   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

A Longitudinal Study on Attention Development in Primary School Children with and without Teacher-Reported Symptoms of ADHD

Frontiers in Psychology, 2017
Background: Prospective longitudinal studies are essential in characterizing cognitive trajectories, yet few of them have been reported on the development of attention processes in children.
Elisabet Suades-González, Elisabet Suades-González, Elisabet Suades-González, Elisabet Suades-González, Joan Forns, Joan Forns, Joan Forns, Raquel García-Esteban, Raquel García-Esteban, Raquel García-Esteban, Mónica López-Vicente, Mónica López-Vicente, Mónica López-Vicente, Mónica López-Vicente, Mikel Esnaola, Mikel Esnaola, Mikel Esnaola, Mar Álvarez-Pedrerol, Mar Álvarez-Pedrerol, Mar Álvarez-Pedrerol, Jordi Julvez, Jordi Julvez, Jordi Julvez, Jordi Julvez, Jordi Julvez, Alejandro Cáceres, Alejandro Cáceres, Xavier Basagaña, Xavier Basagaña, Xavier Basagaña, Anna López-Sala, Jordi Sunyer, Jordi Sunyer, Jordi Sunyer, Jordi Sunyer   +34 more
doaj   +1 more source

The Cerebellum Modulates Attention Network Functioning: Evidence from a Cerebellar Transcranial Direct Current Stimulation and Attention Network Test Study [PDF]

The Cerebellum, 2019
The functional domain of the cerebellum extends beyond its traditional role in motor control. In recent years, this structure has increasingly been considered to play a crucial role even in cognitive performance and attentional processes. Attention is defined as the ability to appropriately allocate processing resources to relevant stimuli.
Mannarelli, Daniela, Pauletti, Caterina, Currà, Antonio, Marinelli, Lucio, Corrado, Alessandra, Delle Chiaie, Roberto, Fattapposta, Francesco   +6 more
openaire   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source