Results 81 to 90 of about 1,966,391 (262)

Structural Brain Correlates of Attention Dysfunction in Lewy Body Dementias and Alzheimer’s Disease

Frontiers in Aging Neuroscience, 2018
Lewy body dementia (LBD) and Alzheimer’s disease (AD) are common forms of dementia that have different clinical profiles but are both commonly associated with attentional deficits.
Ruth A. Cromarty, Julia Schumacher, Sara Graziadio, Peter Gallagher, Alison Killen, Michael J. Firbank, Andrew Blamire, Marcus Kaiser, Marcus Kaiser, Alan J. Thomas, John T. O’Brien, Luis R. Peraza, Luis R. Peraza, John-Paul Taylor   +13 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Behavioral and Neuropsychological Correlates of Emotion Regulation via Attentional Deployment: An Expanded Replication

Europe's Journal of Psychology
Attentional deployment (AD) constitutes an emotion regulation (ER) strategy that shifts the attentional focus to modulate the emotional experience. There are very few experimental paradigms that can study AD.
Christian Salas, Nicolas Núñez, Luz María Pozo, Marko Bremer, Daniel Rojas-Líbano   +4 more
doaj   +1 more source

Neural Correlates of Cognitive Disengagement Syndrome Symptoms in Children: A Magnetoencephalography Study

Brain Sciences
Background/Objectives: Despite the growing recognition of cognitive disengagement syndrome (CDS), previously termed sluggish cognitive tempo, as a distinct dimension of psychopathology, the neural correlates of CDS remain largely unknown. We investigated
Xiaoqian Yu, Jing Xiang, Jeffery N. Epstein, Leanne Tamm, Josalyn A. Foster, Stephen P. Becker   +5 more
doaj   +1 more source

Hyperthermia impairs the executive function using the Attention Network Test

International Journal of Hyperthermia, 2012
The primary aim of this study was to examine the effect of passive hyperthermia on the human attention system using the Attention Network Test (ANT), which has been used in both healthy controls and patients. Using target contrasts between conditions within a Flanker paradigm, the ANT can isolate three essential networks in the attention system ...
Gang, Sun, Xiao, Yang, Qingjun, Jiang, Kai, Liu, Bo, Li, Li, Li, Lun, Zhao, Min, Li   +7 more
openaire   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Repeated measurement of the components of attention of older adults using the two versions of the Attention Network Test (ANT): stability, isolability, robustness, and reliability

Frontiers in Aging Neuroscience, 2011
Ishigami and Klein (2010) showed that scores of the three attention networks (alerting, orienting, and executive control) measured with the two versions of the Attention Network Test (ANT: Fan et al., 2002, Callejas et al., 2005) were robust over 10 ...
Yoko eIshigami, Raymond M Klein
doaj   +1 more source

Test-Retest Reliabilität des Attention-Network-Test bei Schizophrenie

, 2013
Background: Posner and Peterson conceptualized the selective attention into three specific and separate functional components: Alerting, Orienting und executive control, which are associated with frontal, parietal und thalamic neuronal regions. The Attention Network Test (ANT) was developed to measure the efficiency of each of these attentional ...
openaire   +2 more sources

PENGARUH OLAHRAGA AEROB RUTIN TERHADAP ATENSI MAHASISWA FK UNDIP YANG DIUKUR DENGAN ATTENTION NETWORK TEST [PDF]

, 2015
Background: WHO stated that the lack of physical activity has been identified as a risk factor that causes the fourth 3.2 million deaths per year globally.
Indraswari, Darmawati Ayu, LAKSONO, BUDI, Putri, Ismi Mulyanti   +2 more
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