Results 61 to 70 of about 4,439,729 (275)

Natural Is Not Always Better: The Varied Effects of a Natural Environment and Exercise on Affect and Cognition

Frontiers in Psychology, 2021
The Attention Restoration Theory (ART) has been widely cited to account for beneficial effects of natural environments on affect and attention. However, the effects of environment and exercise are not consistent. In a within-subjects design, participants
Janet P. Trammell, Shaya C. Aguilar
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Biophilic design in hospital environments: a rapid review of nature-integrated strategies and patient outcomes

Frontiers in Public Health
Biophilic design has received growing attention as hospitals increasingly seek evidence-based strategies to support patient recovery, psychological comfort, and staff well-being.
Yishan Du, Mei Xie, Yuanyuan Zou
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Neurophysiological Markers of Design-Induced Cognitive Changes: A Feasibility Study with Consumer-Grade Mobile EEG

Brain Sciences
Background: Evidence-based design aims to create healthy environments grounded in scientific data, yet the influence of spatial qualities on cognitive processes remains underexplored.
Nathalie Gerner, David Pickerle, Yvonne Höller, Arnulf Hartl   +3 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Enhancing Biophilia as a Restorative Design Approach in Egyptian Gardens

Proceedings of the International Conference of Contemporary Affairs in Architecture and Urbanism-ICCAUA, 2021
The increasing challenges of enhancing public health for communities and managing stressful daily life style raised the call for finding new methods to reduce stress.
Sara Tarek
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

The more the merrier? Perceived forest biodiversity promotes short‐term mental health and well‐being—A multicentre study

People and Nature
Forests can foster mental health and well‐being. Yet, the contribution of forest biodiversity remains unclear, and experimental research is needed to unravel pathways of biodiversity–health linkages.
Kevin Rozario, Rachel Rui Ying Oh, Melissa Marselle, Erich Schröger, Loïc Gillerot, Quentin Ponette, Douglas Godbold, Daniela Haluza, Katriina Kilpi, Dagmar Müller, Urte Roeber, Kris Verheyen, Bart Muys, Sandra Müller, Taylor Shaw, Aletta Bonn   +15 more
doaj   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

FEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino, Giuliana Fusco, Alfonso De Simone   +2 more
wiley   +1 more source