Results 71 to 80 of about 126,420 (251)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
HorticulturaeAmid growing “nature deficit” associated with urbanization and indoor living, flowering plants are increasingly used to support psychological restoration.
Qinhan Li +9 more
doaj +1 more source
Region Attention Transformer for Medical Image Restoration
Transformer-based methods have demonstrated impressive results in medical image restoration, attributed to the multi-head self-attention (MSA) mechanism in the spatial dimension. However, the majority of existing Transformers conduct attention within fixed and coarsely partitioned regions (\text{e.g.} the entire image or fixed patches), resulting in ...
Zhiwen Yang 0001 +7 more
openaire +2 more sources
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Frontiers in PsychologyObjectiveExercise boredom is a pervasive barrier to physical activity adherence; however, no study has examined it as a primary outcome using a multidimensional boredom measure with temporal tracking across exercise settings.
Haolan Li +4 more
doaj +1 more source
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Ancient Mural Image Restoration Network Using Involution Cascaded Attention Mechanism [PDF]
Jisuanji kexueChinese ancient murals are precious cultural heritage of humanity,recording the social,religious,cultural,and artistic activities of people in various regions of China throughout history.Due to prolonged exposure to the natural environment,many murals ...
ZHOU Qixue, YU Ying, HU Jialv
doaj +1 more source
BuildingsContemporary college students face mounting psychological challenges under high academic pressure, and the design and functionality of campus environments may play a critical role in psychological recovery.
Chuqi Zhong +4 more
doaj +1 more source