Results 81 to 90 of about 8,230,666 (286)

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

A Benchmark Study of DeepLabV3+, U-Net++, and Attention U-Net for Blood Cell Segmentation

open access: yesGreen Intelligent Systems and Applications
Cell segmentation is a critical process in biomedical image analysis. This study evaluated the performance of three state-of-the-art deep learning models—DeepLabV3+, U-Net++, and Attention U-Net—using the Blood Cell Count and Detection (BCCD) dataset, which contains annotated images of blood cells.
Clara Lavita Angelina, Ali Rospawan
openaire   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

CBAM U-Net Model-Based Precipitation Estimation for Chengdu X-band Phased Array Radar [PDF]

open access: yesGaoyuan qixiang
The frequent occurrence of heavy precipitation events poses severe challenges to urban disaster prevention and mitigation. High-resolution quantitative precipitation estimation (QPE) products are of great importance for monitoring intense rainfall ...
Cong ZHOU, Chenghong ZHANG, Yuanchang DONG, Tao ZHANG
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Attention Swin U-Net: Cross-Contextual Attention Mechanism for Skin Lesion Segmentation

open access: yes, 2022
Melanoma is caused by the abnormal growth of melanocytes in human skin. Like other cancers, this life-threatening skin cancer can be treated with early diagnosis.
Zarvani, Maral   +3 more
core  

Wildfire Spread Prediction Using Attention Mechanisms In U-Net [PDF]

open access: yes, 2022
An investigation into using attention mechanisms for better feature extraction in wildfire spread prediction models. This research examines the U-net architecture to achieve image segmentation, a process that partitions images by classifying pixels into ...
Shah, Kamen Haresh
core  

ResDSda_U-net: A novel U-net-based residual network for segmentation of pulmonary nodules in lung CT images

open access: yes, 2023
The timely detection and segmentation of pulmonary nodules in lung computed tomography (CT) images can aid in the early diagnosis and treatment of lung cancer.
Ziheng Zhao (11246670)   +6 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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