Results 61 to 70 of about 1,504,385 (337)
Genomic variations associated with attenuation in Mycobacterium avium subsp paratuberculosis vaccine strains [PDF]
, 2013 BACKGROUND: Mycobacterium avium subspecies paratuberculosis (MAP) whole cell vaccines have been widely used tools in the control of Johne's disease in animals despite being unable to provide complete protection. Current vaccine strains derive from stocks
Bull, TJ +7 more
core +1 more source
PLoS Neglected Tropical Diseases, 2016 Vaccination of humans and animals with live attenuated organisms has proven to be an effective means of combatting some important infectious diseases. In fact, the 20th century witnessed tremendous improvements in human and animal health worldwide as a ...
Aseem Pandey +7 more
semanticscholar +1 more source
Live attenuated oral cholera vaccines
Expert Review of Vaccines, 2006 Live, orally administered, attenuated vaccine strains of Vibrio cholerae have many theoretical advantages over killed vaccines. A single oral inoculation could result in intestinal colonization and rapid immune responses, obviating the need for repetitive dosing. Live V.
Edward T, Ryan +2 more
openaire +2 more sources
Advanced Healthcare Materials, EarlyView.This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad +3 more
wiley +1 more source
, 2013 This investigation evaluated several factors associated with diverse participant enrollment of a clinical trial assessing safety, immunogenicity, and comparative viremia associated with administration of 17-D live, attenuated yellow fever vaccine given ...
Edupuganti, Srilatha +5 more
core +1 more source
Using the nonhuman primate model of HCMV to guide vaccine development. [PDF]
, 2014 The natural history of human cytomegalovirus (HCMV) is inextricably associated with mucosal surfaces. The vast preponderance of primary infections occur following mucosal exposure to infectious virions, and the high seroprevalence of HCMV throughout the ...
Barry, Peter A, Deere, Jesse D
core +3 more sources
Advanced Robotics Research, EarlyView.Gut microbiota and biomarkers are linked to diseases like neurological disorders and metabolic syndromes. Ingestible capsule robots enable minimally invasive gut health assessment. This article proposes a promising direction for the advancement of capsule robots, integrating in situ sampling, real‐time diagnostics, and personalized therapy.
Xizong Chen +3 more
wiley +1 more source
Characterization of potential biomarkers of reactogenicity of licensed antiviral vaccines: randomized controlled clinical trials conducted by the BIOVACSAFE consortium [PDF]
, 2019 Funding text The authors are grateful for the vital contributions of the participating study volunteers, clinicians, nurses, and laboratory technicians at the Surrey study site.
Bodinham, C. +16 more
core +1 more source
Advanced Science, EarlyView.CD207+ dendritic cells (DCs) drive emphysema by promoting CD8⁺ T cell cytotoxicity via Birbeck granule‐dependent MHC‐I antigen presentation. This DC subset is expanded by cigarette smoke‐induced oxidative stress, which triggers granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) release from airway epithelium.
Shurui Xuan +10 more
wiley +1 more source
The role of research in viral disease eradication and elimination programs: Lessons for malaria eradication [PDF]
, 2011 By examining the role research has played in eradication or regional elimination initiatives for three viral diseases-smallpox, poliomyelitis, and measles-we derive nine cross-cutting lessons applicable to malaria eradication.
Breman, JG +6 more
core +1 more source