Results 51 to 60 of about 123,825 (307)
VirusesEquid alphaherpesvirus 1 (EHV-1) has been linked to the emergence of neurological disorders, with the horse racing industry experiencing significant impacts from outbreaks of equine herpesvirus myeloencephalopathy (EHM).
Yue Hu +7 more
doaj +1 more source
Mucosal Immunization Against Pertussis: Lessons From the Past and Perspectives
Frontiers in Immunology, 2021 BackgroundCurrent vaccination strategies against pertussis are sub-optimal. Optimal protection against Bordetella pertussis, the causative agent of pertussis, likely requires mucosal immunity.
Violaine Dubois, Camille Locht
doaj +1 more source
National Institute of Allergy and Infectious Diseases workshop report: "Chlamydia vaccines: The way forward". [PDF]
, 2019 Chlamydia trachomatis (Ct), an intracellular pathogen, is the most common bacterial sexually transmitted infection. In addition to acute cervicitis and urethritis, Ct can lead to serious sequelae of significant public health burden including pelvic ...
Brunham, Robert C +4 more
core +1 more source
Attenuated Vaccines for Augmented Immunity [PDF]
Cell Host & Microbe, 2017 Live attenuated vaccines are more immunogenic and have the capacity to elicit long-lasting immune responses. In two recent studies, Wang et al. (2017) and Si et al. (2016) describe strategies for the generation of live attenuated influenza viruses, which elicited robust humoral, mucosal, and cellular immunity against diverse virus strains.
Stylianos, Bournazos, Jeffrey V, Ravetch
openaire +2 more sources
Advanced Healthcare Materials, EarlyView.We developed a fully human 3D tonsil cell culture system incorporating supportive stromal cells that better sustains and activates immune cells than conventional methods. The model generates stronger, more targeted antibody responses to viral antigens and vaccines, providing a physiologically relevant and entirely human platform for studying immune ...
Maaike V. J. Braham +11 more
wiley +1 more source
Elegant and Innovative Recoding Strategies for Advancing Vaccine Development
VaccinesRecoding strategies have emerged as a promising approach for developing safer and more effective vaccines by altering the genetic structure of microorganisms, such as viruses, without changing their proteins.
François Meurens +2 more
doaj +1 more source
Analysis of Promising Approaches to COVID-19 Vaccine Development
Биопрепараты: Профилактика, диагностика, лечение, 2020 The number of confirmed COVID-19 cases worldwide amounted to 50 million at the beginning of November 2020. This is clearly not enough for the formation of herd immunity, which will prevent repeated outbreaks of the disease.
G. G. Onishchenko +3 more
doaj +1 more source
Frontiers in Veterinary Science, 2022 Immunosuppression in poultry production is a recurrent problem worldwide, and one of the major viral immunosuppressive agents is Infectious Bursal Disease Virus (IBDV). IBDV infections are mostly controlled by using live-attenuated vaccines.
Céline Courtillon +8 more
doaj +1 more source
Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration
Advanced Healthcare Materials, EarlyView.Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu +4 more
wiley +1 more source
Future research to underpin successful peste des petits ruminants virus (PPRV) eradication [PDF]
, 2017 Peste des petits ruminants virus (PPRV) is a significant pathogen of small ruminants and is prevalent in much of Africa, the Near and Middle East and Asia.
Bouna Diop +10 more
core +1 more source