Results 51 to 60 of about 1,089,157 (267)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Recombinant Live-Attenuated Salmonella Vaccine for Veterinary Use
VaccinesVaccination is essential for maintaining animal health, with priority placed on safety and cost effectiveness in veterinary use. The development of recombinant live-attenuated Salmonella vaccines (RASVs) has enabled the construction of balanced lethal ...
Domitila Brzoskowski Chagas +4 more
doaj +1 more source
Attenuation From Shoes and Pads in Equine Nuclear Scintigraphy, With Relevance to Solar Views
Frontiers in Veterinary Science, 2020 Nuclear scintigraphy can be beneficial in the investigation of equine lameness and poor performance. Images obtained through the sole allow for better identification of a region of increased radionuclide uptake in the foot.
Lea Walker +4 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
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, 2004 We discuss the dust attenuation and the star formation rates in the nearby universe obtained from a comparison of far-infrared (IRAS) and ultraviolet (GALEX) observations.
Buat, V.
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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A frequency-selective feedback model of auditory efferent suppression and its implications for the recognition of speech in noise [PDF]
, 2012 The potential contribution of the peripheral auditory efferent system to our understanding of speech in a background of competing noise was studied using a computer model of the auditory periphery and assessed using an automatic speech recognition system.
Brown, G +3 more
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Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
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Application of Ultrasonic Lamb Wave Logging Technology in Bohai Oilfield
Shiyou jixie, 2020 It is restricted and difficult for present sonic logging and sector cement logging technologies used in cementing quality evaluation of low-density cement slurry, casing eccentricity evaluation and casing damage detection. An ultrasonic Lamb wave logging
Han Yaotu +4 more
doaj
Influence of Selected Parameters on Eddy Currents Attenuation in Non-Destructive Inspection
Communications, 2013 Eddy currents attenuation in conductive materials under non-destructive inspection is analyzed in the paper. Influence of selected parameters of the inspection on the attenuation is studied by numerical means.
Ladislav Janousek
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