Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen +8 more
wiley +1 more source
Palliative psychological care in Germany: Results of a national online survey with psychologists and psycho-oncologists in specialist palliative care settings. [PDF]
Scheiner R +4 more
europepmc +1 more source
Determinants of Behavioral Intention towards Mobile Learning in Pakistan: Mediating role of Attitude
Farhina Hameed, Abdul Qayyum
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An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang +10 more
wiley +1 more source
Temporal dynamics of physical activity intentions and attitudes under goal conflict and time pressure in university students. [PDF]
Wang Z +4 more
europepmc +1 more source
By integrating a convergent molecular platform strategy, this study designed a novel dual‐target C5 to combat multidrug‐resistant Gram‐negative bacteria. C5 synergistically enhances antibiotic efficacy by inhibiting efflux pumps and increasing bacterial membrane permeability.
Jiale Dong +11 more
wiley +1 more source
Predictive validity of the attitudes toward medical help-seeking scale
Terry A. DiLorenzo +2 more
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Plants are promising materials for building sustainable and eco‐friendly robots due to their inherent multifunctionality, with actuation playing a crucial role. This article focuses on the physical movements of plants and, from the perspective of actuation characteristics, explores representative plant species and their behaviors, the current state of ...
Kazuya Murakami +8 more
wiley +1 more source
Acupressure for Sleep, Mental Health, and Quality of Life in Hemodialysis Patients: A Systematic Review and Meta-Analysis. [PDF]
Wang Y +7 more
europepmc +1 more source
Survey on the Attitudes of Pharmacy Students in Japan toward Doping and Supplement Intake
Yoshitaka Saito +6 more
openalex +2 more sources

