Results 51 to 60 of about 2,198,265 (159)

Diagnosis of Transthyretin Amyloid Cardiomyopathy

Cardiology and Therapy, 2020
Transthyretin amyloid cardiomyopathy (ATTR-CM) continues to be an easily overlooked, life-threatening, yet treatable cause of heart failure. Furthermore, its elusive diagnosis leads to late or misdiagnosis.
Adam S. Hafeez, Anthony A. Bavry
doaj   +1 more source

Genome‐Wide Association Study Elucidates the Genetic Architecture of Manganese Tolerance in Brassica napus

Plant, Cell &Environment, EarlyView.
ABSTRACT Brassica napus (canola) is a significant contributor to the world's oil production and is cultivated across continents, yet acidic soils with aluminium (Al3+) and manganese (Mn2+) toxicities limit its production. The genetic determinants underlying natural variation for acidic soil tolerance in canola are unknown and need to be determined ...
Harsh Raman, Zetao Bai, Brett McVittie, Sourav Mukherjee, Hugh D. Goold, Yuanyuan Zhang, Nay Chi Khin, Yu Qiu, Nawar Shamaya, Shengyi Liu, Regine Delourme, Barry J. Pogson, Sureshkumar Balasubramanian, Rosy Raman   +13 more
wiley   +1 more source

Titian's Falconer: From Zorzone to Girolamo Cornaro

Renaissance Studies, EarlyView.
ABSTRACT The identity of the sitter in Titian's Falconer and the issue of its dating have been subject to a false, yet very influential assumption: that The Falconer should be dated to a point as late as 1537 in order to connect it to the identity of Zorzone Cornaro (1517–1571), son of Girolamo (1485–1551).
Rachel Healy
wiley   +1 more source

Cardiovascular Diseases: Exploring Epidemiology, Pathophysiology, Risk Factors, and Medicinal Plant‐Based Therapies: A Narrative Review

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Cardiovascular diseases (CVDs) remain the leading cause of global morbidity and mortality, encompassing coronary artery disease, hypertension, heart failure, and cerebrovascular disorders. The global burden of CVD continues to rise, driven by complex interactions among endothelial dysfunction, oxidative stress, inflammation,
Nawfal Hasan Siam, Umme Halima Mithila, Sadia Alam Tisha, Hridoy Saha, Ayesha Binte Mahbub, Farhan Nizam, Johirul Islam, Noushin Tabasumma, Md. Mazharul Islam Chowdhury   +8 more
wiley   +1 more source

Assessing the Clinical Relevance of Blood Soluble Triggering Receptor Expressed on Myeloid Cells 2 in Neurological Diseases

European Journal of Neuroscience, Volume 64, Issue 5, September 2026.
Blood sTREM2 is emerging as a potential biomarker of neuroinflammation, yet its biological significance remains poorly understood. In this study, plasma sTREM2 was quantified in 547 individuals across Alzheimer's disease, mild cognitive impairment, multiple sclerosis, ATTR polyneuropathy, asymptomatic ATTR mutation carriers, and healthy controls ...
Luisa Agnello, Caterina Maria Gambino, Giuseppe Salemi, Vincenzo Di Stefano, Tommaso Piccoli, Anna Masucci, Sabrina Novara, Anna Maria Ciaccio, Fabio Del Ben, Daniela Capello, Marcello Ciaccio   +10 more
wiley   +1 more source

ATTR-CM patients demographic characteristics.

ObjectivesTo identify and describe the profile of potential transthyretin cardiac amyloidosis (ATTR-CM) cases in the Brazilian public health system (SUS), using a predictive machine learning (ML) model.MethodsThis was a retrospective descriptive database
Fabio Fernandes (3386423), Isabella Zuppo Laper (17972784), Marcus Vinicius Simões (5224412), Claudenice Leite Bertoli de Souza (17972790), Ariane de Jesus Lopes de Abreu (14425084), Rafaela Vansan Ferreira (14425090), Edileide de Barros Correia (17972793), Guilherme Silva Julian (8520117), Cecilia Camacho-Hubner (17972787)   +8 more
core   +1 more source

Neuropathy in Val122Ile Hereditary Transthyretin (ATTR) Amyloidosis: A Multicenter Retrospective Cohort Study

Journal of the Peripheral Nervous System, Volume 31, Issue 3, September 2026.
ABSTRACT Background and Aims The Val122Ile ATTR Amyloidosis has traditionally been linked to cardiac manifestations. Recent studies suggest that neuropathy may be relevant. In this study, we characterized its peripheral nerve manifestations in depth. Methods This was a national, multicenter, observational, retrospective study.
Anna Paula Paranhos, Marcela Câmara Machado Costa, Carolina Lavigne Moreira, Diogo Fernandes dos Santos, Marcondes Cavalcante França, Renan Flavio de França Nunes, Osvaldo José Moreira do Nascimento, Jemima Araujo da Silva Batista, Eduardo Boiteux Uchôa Cavalcanti, Cleonisio Leite Rodrigues, Ândrea Virgínia Ferreira Chaves, Marcelo Soares Kerstenetzky, Lara Albuquerque de Brito, Carlo Domênico Marrone, Marcus Vinicius Magno Gonçalves, Pedro José Tomaselli, Wilson Marques   +16 more
wiley   +1 more source

Mandatory and secondary procedures considered for classifying ATTR-CM and ATTR-CM-like cases.

Mandatory and secondary procedures considered for classifying ATTR-CM and ATTR-CM-like cases.
Fabio Fernandes (3386423), Isabella Zuppo Laper (17972784), Marcus Vinicius Simões (5224412), Claudenice Leite Bertoli de Souza (17972790), Ariane de Jesus Lopes de Abreu (14425084), Rafaela Vansan Ferreira (14425090), Edileide de Barros Correia (17972793), Guilherme Silva Julian (8520117), Cecilia Camacho-Hubner (17972787)   +8 more
core   +1 more source

Transthyretin Amyloid Cardiomyopathy in Women: Epidemiology, Diagnostic Delay, and Clinical Implications

Cardiology and Therapy
Transthyretin amyloid cardiomyopathy (ATTR-CM) is an underdiagnosed cause of heart failure, resulting from the deposition of misfolded transthyretin protein in the myocardium.
Avni Madhani, Bhavya Ancha, Kevin M. Alexander, Joban Vaishnav   +3 more
doaj   +1 more source

Evaluating the Performance and Potential Bias of Predictive Models for Detection of Transthyretin Cardiac Amyloidosis

JACC: Advances
Background: Delays in the diagnosis of transthyretin amyloid cardiomyopathy (ATTR-CM) contribute to the significant morbidity of the condition, especially in the era of disease-modifying therapies.
Jonathan Hourmozdi, MD, MSAI, MA, Nicholas Easton, MSAI, Simon Benigeri, MSAI, James D. Thomas, MD, Akhil Narang, MD, David Ouyang, MD, Grant Duffy, BS, Ross Upton, PhD, Will Hawkes, PhD, Ashley Akerman, PhD, Ike Okwuosa, MD, Adrienne Kline, MD, PhD, Abel N. Kho, MD, Yuan Luo, PhD, Sanjiv J. Shah, MD, Faraz S. Ahmad, MD, MS   +15 more
doaj   +1 more source