Results 91 to 100 of about 49,586 (211)
Parabolic and near-parabolic renormalizations for local degree three
The invariant class under parabolic and near-parabolic renormalizations constructed by Inou and Shishikura has been proved extremely useful in recent years. It leads to several important progresses on the dynamics of certain holomorphic maps with a local
Yang, Fei
core
ABSTRACT Amyloidosis is a rare disease associated with the deposition of misfolded proteins that damage multiple organs, leading to a wide range of symptoms. The most frequently implicated proteins in amyloidosis include immunoglobulin Free Light Chains (FLC), related to AL amyloidosis, and transthyretin (TTR), which is responsible for ATTR amyloidosis.
Paulina Kryszpin +8 more
wiley +1 more source
Aim: The six-minute walk test (6MWT) is a common measure of functional capacity in patients with heart failure (HF). Primary clinical study end points in cardiomyopathy (CM) trials, including transthyretin-mediated amyloidosis with CM (ATTR-CM), are ...
Jose Nativi-Nicolau +8 more
doaj +1 more source
Transthyretin amyloidosis (ATTR), a rare systemic disorder characterized by misfolded transthyretin (TTR) protein aggregation, predominantly affects the heart and peripheral nervous system.
Fen Li +6 more
doaj +1 more source
Background The coexistence of transthyretin cardiac amyloidosis (ATTR‐CA) and aortic stenosis (AS) is increasingly recognized, but the clinical consequences are unclear.
Ahmad Masri +10 more
doaj +1 more source
RNA‐Based Therapies for Inherited Metabolic Disorders
ABSTRACT Inherited metabolic disorders (IMDs) are a diverse and complex group of genetic conditions resulting from deficiencies in enzymes, transporters, or cofactors. These deficiencies lead to metabolic dysfunction and severe clinical consequences. Despite significant progress in understanding their molecular basis, treatment options remain limited ...
Reddy Sreekanth Vootukuri +5 more
wiley +1 more source
ABSTRACT This work considers branch‐price‐and‐cut algorithms for variants of the vehicle‐routing problem in which subset‐row inequalities (SRIs) are used to strengthen the linear relaxation. SRIs often help to substantially reduce the size of the branch‐and‐bound search tree.
Stefan Faldum +2 more
wiley +1 more source
Conservative Management of Bilateral Spontaneous Pneumothorax
Bilateral simultaneous spontaneous pneumothorax is a rare occurrence that generally requires prompt intervention. We report a case of simultaneous bilateral spontaneous pneumothorax that was conservatively managed. ABSTRACT Bilateral simultaneous spontaneous pneumothorax is a rare occurrence that generally requires prompt intervention. We report a case
Hanson Siu, Chuan T. Foo
wiley +1 more source
BackgroundAccumulation of transthyretin amyloids (ATTR) is detected in ligamentum flavum in about 1/3 of patients underwent surgery for spinal stenosis. However, the significance of this finding is not known.
Domantas Tamasauskas +3 more
doaj +1 more source
Incremental Construction of Large Specifications: Case Study and Techniques
The RODIN project is an EU-funded project concerned with the provision of methods and tools for rigorous development of complex software-based systems.
Butler, Michael, Evans, Neil
core

