Results 11 to 20 of about 17,377 (218)

A phenomap of TTR amyloidosis to aid diagnostic screening

ESC Heart Failure
Cardiac amyloidosis due to transthyretin (ATTR) remains an underdiagnosed cause of cardiomyopathy. As awareness of the disease grows and referrals for ATTR increase, clinicians are likely to encounter more atypical forms of the condition in clinical ...
Alexios S. Antonopoulos, Theodoros Tsampras, George Lazaros, Konstantinos Tsioufis, Charalambos Vlachopoulos   +4 more
doaj   +2 more sources

Quantitative Proteomics of Plasma-Derived Extracellular Vesicles Reveals a Plasminogen-Centered Protein Network in Transthyretin Cardiac Amyloidosis [PDF]

JACC: Advances
Background: The prognosis of patients with transthyretin cardiac amyloidosis (ATTR) remains poor; this is primarily due to late diagnosis, when irreversible damage has already occurred.
Amira Zaroui, MD, Damien Habert, MSc, Benoit Vallée, MSc, Mounira Kharoubi, PhD, Soraya Fellahi, PharmD, Benoit Vingert, PhD, Michel Seve, PharmD, PhD, Ilaria Cascone, PhD, Vincent Audard, MD, PhD, Emmanuel Itti, MD, PhD, Hajer Abroud, PharmD, Arnault Galat, MD, Thibaud Damy, MD, PhD, Sandrine Bourgoin-Voillard, PhD, Valérie Molinier-Frenkel, MD, PhD   +14 more
doaj   +2 more sources

Real‐world characteristics and treatment of cardiac transthyretin amyloidosis: A multicentre, observational study

ESC Heart Failure
Aims Data on the clinical profiles of patients with transthyretin amyloidosis cardiomyopathy (ATTR‐CM) in the post‐approval era of tafamidis 61 mg are lacking.
Richard J. Nies, Svenja Ney, Ingrid Kindermann, Yvonne Bewarder, Angela Zimmer, Fabian Knebel, Katrin Hahn, Sebastian Spethmann, Peter Luedike, Lars Michel, Tienush Rassaf, Maria Papathanasiou, Stefan Störk, Vladimir Cejka, Amin Polzin, Fabian Voss, Malte Kelm, Bernhard Unsöld, Christine Meindl, Michael Paulus, Ali Yilmaz, Bishwas Chamling, Caroline Morbach, Roman Pfister   +23 more
doaj   +2 more sources

Subclinical Cardiac Involvement in Asymptomatic ATTR Mutation Carriers: Insights from Cardiac MRI, Myocardial Strain, and Mapping Techniques

Journal of Cardiovascular Development and Disease
Transthyretin cardiac amyloidosis (ATTR-CA) leads to myocardial infiltration, affecting prognosis and survival. Diagnosing early-stage ATTR-CA remains challenging due to its subtle manifestations.
Luca Conia, Daria Filatova, Giacomo Pambianchi, Livia Marchitelli, Giulia Cundari, Giuseppe Stancanelli, Maria Alfarano, Giulia Marchionni, Cristina Chimenti, Carlo Catalano, Nicola Galea   +10 more
doaj   +2 more sources

Reply: Val122Ile mt-ATTR Has a Worse Survival Than wt-ATTR Cardiac Amyloidosis.

Journal of the American College of Cardiology, 2017
not available reply to Singh A, Geller HI, Falk RH. Val122Ile mt-ATTR Has a Worse Survival Than wt-ATTR Cardiac Amyloidosis. J Am Coll Cardiol.
Maurer, Mathew S, Mundayat, Rajiv, RAPEZZI, CLAUDIO   +2 more
core   +6 more sources

Prevalence of anxiety and depression symptoms in a sample of outpatients with ATTR cardiac amyloidosis [PDF]

Frontiers in Psychology, 2023
Patients with ATTR cardiac amyloidosis (ATTR-CA) face rare disease that could negatively influence psychological well-being with consequences on the course of the disease and quality of life.
Martina Smorti, Lucia Ponti, Lucia Ponti, Francesco Soffio, Alessia Argirò, Alessia Argirò, Federico Perfetto, Federico Perfetto, Mattia Zampieri, Mattia Zampieri, Carlotta Mazzoni, Alessia Tomberli, Marco Allinovi, Carlo Di Mario, Iacopo Olivotto, Francesco Cappelli, Francesco Cappelli   +16 more
doaj   +2 more sources

Epidemiology of transthyretin (ATTR) amyloidosis: a systematic literature review

Orphanet Journal of Rare Diseases
Introduction Significant advances in the treatment of transthyretin (ATTR) amyloidosis has led to an evolving understanding of the epidemiology of this condition. This systematic literature review (SLR) aims to synthesize current evidence on epidemiology
Diego Delgado, Firas Dabbous, Nitin Shivappa, Faizan Mazhar, Eric Wittbrodt, Divya Shridharmurthy, Krister Järbrink   +6 more
doaj   +2 more sources

Localized Tracheobronchial Transthyretin Amyloidosis Diagnosed After Hemoptysis: A Case Report [PDF]

Respirol Case Rep
Pulmonary involvement in transthyretin amyloidosis (ATTR) is rare, and tracheobronchial involvement is particularly uncommon. We report localized wild‐type ATTR presenting with hemoptysis and diagnosed by bronchoscopic biopsy showing Congo red‐positive transthyretin deposition. ABSTRACT Pulmonary involvement in transthyretin amyloidosis (ATTR) is rare,
Inoue K, Tanaka Y, Yanagi M, Michimata H, Nagahisa Y, Kondoh S.   +5 more
europepmc   +2 more sources

Transthyretin Amyloid Cardiomyopathy in Women: Epidemiology, Diagnostic Delay, and Clinical Implications [PDF]

Cardiology and Therapy
Transthyretin amyloid cardiomyopathy (ATTR-CM) is an underdiagnosed cause of heart failure, resulting from the deposition of misfolded transthyretin protein in the myocardium.
Avni Madhani, Bhavya Ancha, Kevin M. Alexander, Joban Vaishnav   +3 more
doaj   +2 more sources

Diflunisal for ATTR Cardiac Amyloidosis [PDF]

Congestive Heart Failure, 2012
©2012 Wiley Periodicals Inc.Transthyretin (TTR) cardiac amyloidosis is an important, often under‐recognized and potentially modifiable cause of heart failure with a preserved ejection fraction. The only proven treatment is liver or combined heart/liver transplantation, which, although effective, is not suitable for the vast majority of older adults ...
Adam, Castaño, Stephen, Helmke, Julissa, Alvarez, Susan, Delisle, Mathew S, Maurer   +4 more
openaire   +2 more sources