Results 91 to 100 of about 8,194 (217)

Diagnosing Smoldering Multiple Myeloma and Light Chain Amyloidosis in the Setting of Severe Transthyretin Amyloid Cardiomyopathy and Extracardiac Sarcoidosis

Annals of Internal Medicine: Clinical Cases
Light chain (AL) amyloidosis involves deposition of monoclonal immunoglobulin light chain-derived amyloid fibrils, whereas ATTR amyloidosis involves deposition of insoluble antiparallel beta-pleated protein within tissues, leading to organ-specific ...
Robert A. Churchill, Andrew Rosenbaum
doaj   +1 more source

Atrial cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 727-729, April 2025.
Wojciech Kosmala, Monika Przewłocka‐Kosmala   +1 more
wiley   +1 more source

Wild Type Transthyretin Amyloid Cardiomyopathy Hidden Under Ablation‐Refractory Atrial Arrhythmias and the Potential Contribution of Tafamidis in Rhythm Control

Journal of Arrhythmia, Volume 42, Issue 1, February 2026.
An octogenarian man with a history of multiple catheter ablation failures for atrial fibrillation and tachycardia was diagnosed with transthyretin amyloid cardiomyopathy. After 1 year of tafamidis therapy, the patient experienced spontaneous restoration of sinus rhythm, and follow‐up image of 99mTc‐pyrophosphate scintigraphy revealed a marked decrease ...
Tomoki Horie, Yasutoshi Nagata, Toshihiro Nozato, Shinsuke Miyazaki, Takashi Ashikaga   +4 more
wiley   +1 more source

Percutaneous Left Atrial Appendage Occlusion for Atrial Fibrillation in Cardiac Amyloidosis

Journal of Arrhythmia, Volume 42, Issue 1, February 2026.
Left atrial appendage occlusion‐related outcomes in patients with amyloid cardiomyopathy. ABSTRACT Background Cardiac amyloidosis (CA) is frequently complicated by atrial fibrillation (AF), yet outcomes after left atrial appendage occlusion (LAAO) in this population remain poorly defined.
Abdul Hakim Almakadma, Ramzi Ibrahim, Hoang Nhat Pham, Eiad Habib, Ahmed K. Mahmoud, Kamal Awad, Mayurkumar D. Bhakta, Eric H. Yang, Hicham Z. El Masry, Chadi Ayoub, Reza Arsanjani   +10 more
wiley   +1 more source

Catheter Ablation and Device Therapy in Patients With Transthyretin Amyloid Cardiomyopathy: A Review of Non‐Pharmacological Therapy

Journal of Arrhythmia, Volume 42, Issue 1, February 2026.
Transthyretin amyloid cardiomyopathy (ATTR‐CM) frequently coexists with atrial fibrillation, atrial flutter, and atrial tachycardia as well as occasionally ventricular arrhythmias and often conduction abnormalities, necessitating management for arrhythmias.
Hisanori Kanazawa, Tadashi Hoshiyama, Shozo Kaneko, Yusei Kawahara, Yuichiro Tsuruta, Yuta Tsurusaki, Kohei Matsunaga, Shunsuke Tamanoi, Naoto Kuyama, Hiroki Usuku, Eiichiro Yamamoto, Yasuhiro Izumiya, Kenichi Tsujita   +12 more
wiley   +1 more source

Single-centre experience on transthyretin familial amyloid polyneuropathy : case series and literature review [PDF]

, 2018
Familial amyloid polyneuropathy (FAP) is a most often length-dependent axonal neuropathy, often part of a multisystem disorder also affecting other organs, such as cardiac, gastrointestinal, genitourinary, renal, meningeal and eye tissue.
De Bleecker, Jan, De Pauw, Michel, Martens, Broes   +2 more
core   +2 more sources

A Review of Tafamidis for the Treatment of Transthyretin-Related Amyloidosis [PDF]

, 2015
Transthyretin (TTR)-related amyloidosis (ATTR) is a devastating disease which affects a combination of organs including the heart and the peripheral nerves, and which has a fatal outcome if not treated within a average of 10 years.
Benson, Merril D., Waddington Cruz, Márcia   +1 more
core   +1 more source

Afectación cardiovascular en la amiloidosis. Revisón de la literatura y puesta al día [PDF]

, 2016
La amiloidosis es una enfermedad infiltrativa provocada por el depósito extracelular de material proteico fibrilar en los tejidos, existiendo formas localizadas y sistémicas. En esta última, destacan por su frecuencia la amiloidosis AL o primaria, que es
Rodrigo Manjón, Alejandro
core  

A Rare Culprit or an Elusive Culprit in Disguise? Unraveling Wild-Type ATTR Cardiac Amyloidosis in Heart Failure With Reduced Ejection Fraction

Journal of Investigative Medicine High Impact Case Reports
Cardiac amyloidosis (CA) is a rare disorder caused by the deposition of abnormal proteins called amyloid in the myocardium, leading to dysfunction. The 2 most common forms of amyloidosis are AL (light chain) and ATTR (transthyretin).
Jose Loayza Pintado MD, Taiwo Ajani MD, Daniela Hernandez MD, Everardo Cobos MD   +3 more
doaj   +1 more source

Inhibition of the mechano-enzymatic amyloidogenesis of transthyretin: role of ligand affinity, binding cooperativity and occupancy of the inner channel [PDF]

, 2017
Dissociation of the native transthyretin (TTR) tetramer is widely accepted as the critical step in TTR amyloid fibrillogenesis. It is modelled by exposure of the protein to non-physiological low pH in vitro and is inhibited by small molecule compounds ...
Bellotti, Vittorio, Corazza, Alessandra, Faravelli, Giulia, Gillmore, Julian D, Giorgetti, Sofia, Hawkins, Philip N, Mangione, P. Patrizia, Pepys, Mark B, Porcari, Riccardo, Raimondi, Sara, Taylor, Graham W, Verona, Guglielmo   +11 more
core   +2 more sources