Results 61 to 70 of about 8,194 (217)

Val122Ile mt-ATTR Has a Worse Survival Than wt-ATTR Cardiac Amyloidosis

Journal of the American College of Cardiology, 2017
Maurer et al. [(1)][1] reported results from the THAOS (Transthyretin Amyloid Outcome Survey) registry of transthyretin cardiac amyloid (ATTR) amyloidosis, in which they compared differences between patients carrying wild-type ATTR (wt-ATTR) cardiac amyloidosis and those carrying the mutant ...
Avinainder, Singh, Hallie I, Geller, Rodney H, Falk   +2 more
openaire   +2 more sources

Exercise limitations in amyloid cardiomyopathy assessed by cardiopulmonary exercise testing—A multicentre study

ESC Heart Failure, Volume 12, Issue 2, Page 1326-1335, April 2025.
Abstract Aims Amyloid cardiomyopathy is caused by the deposition of light chain (AL) or transthyretin amyloid (ATTR) fibrils, that leads to a restrictive cardiomyopathy, often resulting in heart failure (HF) with preserved or reduced ejection fraction.
Robin Willixhofer, Mauro Contini, Michele Emdin, Damiano Magrì, Alice Bonomi, Elisabetta Salvioni, Fabrizio Celeste, Alberico Del Torto, Claudio Passino, Christophe D.J. Capelle, Chiara Arzilli, Emiliano Fiori, Nicolò Capra, Christina Kronberger, Nikita Ermolaev, Andreas Kammerlander, Beatrice Musumeci, Giuseppe Vergaro, Vincenzo Castiglione, René Rettl, Giacomo Tini, Andrea Baggiano, Iacopo Fabiani, Susanna Sciomer, Roza Badr Eslam, Piergiuseppe Agostoni   +25 more
wiley   +1 more source

Dynamic changes of intracellular signals in ATTR Tyr114Cys amyloidosis

Biochemistry and Biophysics Reports
Hereditary transthyretin (TTR) amyloidosis (ATTRv amyloidosis) is an autosomal dominant disease caused by various TTR mutations. Despite the fact that ATTR Tyr114Cys (p.Tyr134Cys) amyloidosis (tyrosine to cysteine at codon 114) exhibits poorer prognosis ...
Kenta Ouchi, Takeshi Masuda, Kou Yonemaru, Kaori Isono, Yuki Ohya, Nobuaki Shiraki, Masayoshi Tasaki, Yukihiro Inomata, Mitsuharu Ueda, Takumi Era, Shoen Kume, Yukio Ando, Hirofumi Jono   +12 more
doaj   +1 more source

Amiloidose renal: classificação de 102 casos consecutivos [PDF]

, 2014
Amyloidoses are a group of heterogeneous diseases classified according to the nature of their causative amyloid proteins. Commonly, paraffin-embedded tissue is used for the typing of amyloid by immunohistochemistry.
Lobato, L., Moreira, L., Oliveira, J., Pereira, P., Pinho-Costa, P., Sampaio, S., Tavares, I., Vaz, R., Vizcaíno, J.   +8 more
core  

Diagnostic sensitivity of abdominal fat aspiration in cardiac amyloidosis [PDF]

, 2017
Aims: Congo red staining of an endomyocardial biopsy is the diagnostic gold-standard in suspected cardiac amyloidosis (CA), but the procedure is associated with the risk, albeit small, of serious complications, and delay in diagnosis due to the ...
Botcher, N, Fontana, M, Gilbertson, JA, Gillmore, JD, Gonzalez-Lopez, E, Hawkins, PN, Lachmann, HJ, Mahmood, S, Petrie, A, Quarta, CC, Rezk, T, Rowczenio, D, Sachchithanantham, S, Wechalekar, AD, Whelan, CJ, Youngstein, T   +15 more
core   +1 more source

Transthyretin Amyloidosis: Chaperone Concentration Changes and Increased Proteolysis in the Pathway to Disease [PDF]

, 2015
Transthyretin amyloidosis is a conformational pathology characterized by the extracellular formation of amyloid deposits and the progressive impairment of the peripheral nervous system.
Barroso, E, Coelho, A, Cordeiro, C, Costa, G, Ferreira, A, Gilberto, S, Gomes, R, Mateus, E, Ponces Freire, A, Ribeiro, R, Ribeiro-Silva, C   +10 more
core  

End-Stage Renal Disease in Familial Amyloidosis ATTR Val30Met: A [PDF]

, 2003
Transplant Proc. 2003 May;35(3):1116-20. End-stage renal disease in familial amyloidosis ATTR Val30Met: a definitive indication to combined liver-kidney transplantation.
Beirão, I., Henriques, A.C., Lobato, L., Miranda, H.P., Pereira, M.C., Sarmento, A.M., Seca, R., Teixeira, M., Ventura, A.   +8 more
core  

Editorial Board [PDF]

, 2004
Aim: Cardiac troponins and natriuretic peptides are established for risk stratification in light-chain amyloidosis. Data on cardiac biomarkers in transthyretin amyloidosis (ATTR) are lacking.
, Damy, T., Kristen, A.V., Maurer, M.S., Mundayat, R., Rapezzi, C., Suhr, O.B.   +6 more
core   +3 more sources

Heart transplantation in hereditary ATTR amyloidosis [PDF]

Orphanet Journal of Rare Diseases, 2015
Systemic amyloidosis related to mutation of TTR gene can be complicated with Familial Amyloid Cardiomyopathy (TTR-FAC), a severe and life threatening form of heart failure with preserved ejection fraction, with a poor prognosis. To date there is no proven effective specific treatment against TTR-FAC, and the usual treatments of chronic heart failure ...
openaire   +1 more source

Ultra High‐Resolution Ultrasound Features of Carpal Tunnel Syndrome in Transthyretin Amyloidosis: A Cross‐Sectional Study

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Transthyretin amyloidosis (ATTR), including hereditary (hATTR) and wild‐type (wtATTR), often presents initially as carpal tunnel syndrome (CTS), often preceding systemic symptoms by several years. Ultra high‐resolution ultrasound (UHRUS) offers detailed visualization of peripheral nerve morphology, but its application in ATTR‐
Rachana K. Gandhi Mehta, Nicholas Miller, Michael S. Cartwright, Rebecca Traub, Joni Evans   +4 more
wiley   +1 more source