Results 61 to 70 of about 134,165 (299)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Dynamic double layer force between charged surfaces
Physical Review Research, 2020 We develop a theory for the “dynamic double layer force” between charged surfaces in an electrolyte under a time-dependent voltage. Specifically, the force between two planar surfaces is calculated within the Poisson-Nernst-Planck framework for dilute ...
Bhavya Balu, Aditya S. Khair
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Force measurement using double series magnetic suspension
Nihon Kikai Gakkai ronbunshu, 2014 Double Series magnetic suspension is applied to force measurement. In a double series magnetic suspension system, two floators are suspended with a single electromagnet. The attractive force of the electromagnet directly acts on the first (upper) floator
Takeshi MIZUNO +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Multi UAV Cluster Control Method Based on Virtual Core in Improved Artificial Potential Field
IEEE Access, 2020 In this paper, a method of multi UAV cluster control based on improved artificial potential field (APF) is proposed. The k-means method is used to integrate and optimize the attractive force between UAVs, and the concept of virtual core is introduced to ...
Enming Wu +4 more
doaj +1 more source
Agronomy, 2023 Aggregate stability is a key factor in the evaluation of soil structure and erosion resistance, which is largely influenced by soil electric field and particle interaction.
Zhe Liu +6 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Systematically altering the hydrophobic nanobubble bridging capillary force from attractive to repulsive [PDF]
, 2009 Atomic force microscopy (AFM) was used to examine how ethanol/water concentration affects the nanobubble bridging Capillary force between a hydrophobic silica colloidal probe and a hydrophobic silica wafer. Nanobubbles were produced on the solid surfaces
Hampton, Marc A., Nguyen, Anh V.
core +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source