Results 101 to 110 of about 26,964 (314)
Unity of Cosmological Inflation Attractors [PDF]
Recently, several broad classes of inflationary models have been discovered whose cosmological predictions, in excellent agreement with Planck, are stable with respect to significant modifications of the inflaton potential.
Galante, Mario +4 more
core +1 more source
Systems of ordinary differential equations that appear in gene regulatory networks theory are considered. We are focused on asymptotical behavior of solutions.
Brokan Eduard, Sadyrbaev Felix
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Global Attractors of Non-autonomous Difference Equations [PDF]
The article is devoted to the study of global attractors of quasi-linear non-autonomous difference equations, in particular we give the conditions for the existence of a compact global attractor.
David Cheban +2 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Energy-optimal steering of transitions through a fractal basin boundary. [PDF]
We study fluctuational transitions in a discrete dy- namical system having two co-existing attractors in phase space, separated by a fractal basin boundary. It is shown that transitions occur via a unique ac- cessible point on the boundary.
Luchinsky, D. G. +3 more
core
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
The Global Attractor of the Allen-Cahn Equation on the Sphere
In this paper we study the attractor of a parabolic semiflow generated by a singularly perturbed PDE with a non-linear term given by a bistable potential, in an oval surface; the Allen-Cahn equation being a prototypical example.
David Medina, Pablo Padilla
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source

