Results 121 to 130 of about 26,964 (314)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Recent progress in attractors for quintic wave equations [PDF]
, 2009 summary:We report on new results concerning the global well-posedness, dissipativity and attractors for the quintic wave equations in bounded domains of $\mathbb R^3$ with damping terms of the form $(-\Delta _x)^\theta \partial _t u$, where $\theta =0 ...
Savostianov, Anton +4 more
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Modeling Dimensions of Prosodic Prominence
Frontiers in Communication, 2019 Detailed modifications both in the laryngeal as well as in the supra-laryngeal domain have been shown to be used by speakers of German to express prosodic prominence.
Simon Roessig, Doris Mücke
doaj +1 more source
Bounding the attractor of an IFS
Information Processing Letters, 1997 Fractal images defined by an iterated function system (IFS) are specified by a finite number of contractive affine transformations. In order to plot the attractor of an IFS on the screen of a digital computer, it is necessary to determine a bounding area for the attractor.
Edalat, A, Sharp, D, While, L
openaire +3 more sources
FEBS Letters, EarlyView.Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source
Integrated circuit generating 3- and 5-scroll attractors [PDF]
, 2012 This paper introduces the experimental realization of the first integrated circuit of a multi-scroll continuous chaotic oscillator showing 3- and 5-scroll attractors. It is based on a variant of the Chua’s system.
ESTEBAN TLELO CUAUTLE +3 more
core
Convergence to local random attractors [PDF]
, 2013 This is a preprint of an article whose final and definitive form has been published in DYNAMICAL SYSTEMS © 2003 copyright Taylor & Francis; DYNAMICAL SYSTEMS is available online at: http://www.informaworld.com/openurl?genre=article&issn= 1468-9367&volume=
Ashwin, Peter, Ochs, Gunter
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source