Results 131 to 140 of about 900,077 (368)
The dimension of the boundary of the Lévy Dragon
International Journal of Mathematics and Mathematical Sciences, 1997 In this paper we describe the computations done by the authors in determining the dimension of the boundary of the Lévy Dragon. A general theory was developed for calculating the dimension of a self-similar tile and the theory was applied to this ...
P. Duvall, J. Keesling
doaj +1 more source
PLoS ONE, 2013 The experimental observations and numerical studies with dissipative metabolic networks have shown that cellular enzymatic activity self-organizes spontaneously leading to the emergence of a Systemic Metabolic Structure in the cell, characterized by a set of different enzymatic reactions always locked into active states (metabolic core) while the rest ...
Fuente, Ildefonso M. de la +3 more
openaire +6 more sources
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
, 2018 Under consideration is the damped semilinear wave equation \[ u_{tt}+u_t-\Delta u+u+f(u)=0 \] in a bounded domain $\Omega$ in $\mathbb{R}^3$ subject to an acoustic boundary condition with a singular perturbation, which we term "massless acoustic ...
Shomberg, Joseph L.
core
Constructing Infinitely Many Attractors in a Programmable Chaotic Circuit
IEEE Access, 2018 In this paper, we modify the Sprott M chaotic system to provide infinitely many co-existing attractors by replacing the offset boosting parameter with a periodic function giving what we call a self-reproducing system.
Chunbiao Li +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Non-wandering Fatou Components for Strongly Attracting Polynomial Skew Products [PDF]
, 2019 Zhuchao Ji
openalex +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
362. Cell-Specific Transcriptional Regulatory Domains Attract γ-Retroviral Integration in the Human Genome [PDF]
, 2009 openalex +1 more source