Proportion of mesothelioma attributable to living in industrially contaminated areas in Italy
OBJECTIVES: The aim of this study was to estimate the attributable proportion (AP) of mesothelioma resulting from living in or close to major Italian industrially contaminated areas. METHODS: For populations living close to 39 sites of "national priority
Roberto Pasetto +7 more
doaj +1 more source
Revisiting sequential attributable fractions
Background In 1995, Eide and Gefeller introduced the concepts of sequential and average attributable fractions as methods to partition the risk of disease among differing exposures.
John Ferguson +2 more
doaj +1 more source
Interpreting Tests of Forward Discount Bias Using Survey Data on Exchange Rate Expectations [PDF]
Survey data on exchange rate expectations are used to divide the forward discount into expected depreciation and a risk premium. Our starting point is the common test oh whether the forward discount is an unbiased predictor of future changes in the spot ...
Jeffrey A. Frankel, Kenneth A. Froot
core
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Obesity and diabetes in New Zealand [PDF]
Obesity is a risk factor for diabetes, cardiovascular disease, musculoskeletal disorders, and some cancers. Introduction It is estimated that 1.1 million adults are obese in New Zealand (that is, they have a BMI or Body Mass Index of 30 or more ...
Alexandra Marett
core
Financial Regulation and Risk Management:Addressing Risk Challenges in a Changing Financial Environment [PDF]
Amongst other goals, this paper aims to address complexities and challenges faced by regulators in identifying and assessing risk, problems arising from different perceptions of risk, and solutions aimed at countering problems of risk regulation.
Ojo, Mariane.B.
core
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Breve Guida Alle Misure di Impatto Utilizzate in Epidemiologia e Sanità Pubblica
non disponibile (Epidemiology_statistics)
Francesco Franco, Anteo Di Napoli
doaj +1 more source
Consumption of sugar sweetened beverages, artificially sweetened beverages, and fruit juice and incidence of type 2 diabetes: systematic review, meta-analysis, and estimation of population attributable fraction. [PDF]
OBJECTIVES: To examine the prospective associations between consumption of sugar sweetened beverages, artificially sweetened beverages, and fruit juice with type 2 diabetes before and after adjustment for adiposity, and to estimate the population ...
Bhupathiraju, Shilpa N +6 more
core +8 more sources
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source

