Results 111 to 120 of about 5,061,029 (315)

TOPSIS Method for Probabilistic Linguistic MAGDM with Entropy Weight and Its Application to Supplier Selection of New Agricultural Machinery Products

Entropy, 2019
In multiple attribute group decision making (MAGDM) problems, uncertain decision information is well-represented by linguistic term sets (LTSs). These LTSs are easily converted into probabilistic linguistic sets (PLTSs). In this paper, a TOPSIS method is
Jianping Lu, Cun Wei, Jiang Wu, Guiwu Wei   +3 more
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Analytical hierarchy process (AHP) approach to the selection of heritage building element

MATEC Web of Conferences, 2018
In order to bring the reduction of damage and defect of heritage buildings, the management needs to use an suitable methodology approach for the element heritage building. The goal of this paper is to make the selection of criteria and attribute by using
Zuraidi Siti Nor Fatimah, Abdul Rahman Mohammad Ashraf, Akasah Zainal Abidin   +2 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Attribute Selection for Stroke Prediction

Acta Mechanica et Automatica, 2019
Abstract Stroke is the third most common cause of death and the most common cause of long-term disability among adults around theworld. Therefore, stroke prediction and diagnosis is a very important issue. Data mining techniques come in handy to help determine the correlations between individual patient characterisation data, that is ...
openaire   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Semi-Supervised Attribute Selection Algorithms for Partially Labeled Multiset-Valued Data

Mathematics
In machine learning, when the labeled portion of data needs to be processed, a semi-supervised learning algorithm is used. A dataset with missing attribute values or labels is referred to as an incomplete information system.
Yuanzi He, Jiali He, Haotian Liu, Zhaowen Li   +3 more
doaj   +1 more source

An Attribute Selection For Severity Level Determination According To The Support Vector Machine Classification Result

, 2012
Determination of bug severity level is needed in fixing bug. Actually, in bug-tracking system, there is around 14 attributes used for defining a bug. But, all this time we do not know which attributes are highly influential for this. In this research, a
Ghaluh Indah Permata , Sari
core  

Non-deterministic attribute selection in reference production [PDF]

, 2011
In producing identifying descriptions, speakers often overspecify and manifest preferences for certain at-tributes. However, current computational models which incorporate this observation tend not to make precise predictions about when and how much ...
33rd Annual Meeting of the Cognitive Science Society, Gatt, Albert, Krahmer, Emiel, van Deemter, Kees, van Gompel, Roger P. G.   +4 more
core  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source