Results 71 to 80 of about 23,004 (191)

Evaluation of preclinical antipsychotic models used to support first‐in‐human clinical trials

British Journal of Pharmacology, Volume 183, Issue 7, Page 1364-1389, April 2026.
Abstract Schizophrenia is regarded as a complex and heterogeneous psychiatric disorder, characterised by diverse symptoms and comorbidities, which complicate both clinical management and drug development. Current pharmacological treatment, primarily based on dopamine D2 receptor antagonism or partial agonism, which has not markedly progressed since the
Thi Viet Ha Nguyen, Declan P. McKernan, John P. Kelly   +2 more
wiley   +1 more source

Hospitalization and cost after switching from atypical to typical antipsychotics in schizophrenia patients in Thailand

ClinicoEconomics and Outcomes Research, 2016
Tuanthon Boonlue,1,2 Suphat Subongkot,1,2 Piyameth Dilokthornsakul,3,4 Ronnachai Kongsakon,5 Oraluck Pattanaprateep,6 Orabhorn Suanchang,7 Nathorn Chaiyakunapruk3,8–10 1Clinical Pharmacy Division, Faculty of Pharmaceutical Sciences, Khon Kaen ...
Boonlue T, Subongkot S, Dilokthornsakul P, Kongsakon R, Pattanaprateep O, Suanchang O, Chaiyakunapruk N   +6 more
doaj  

Antipsychotic Use Among Intellectually Disabled Individuals With Rare Genetic Variants That Confer Risk for Schizophrenia

Journal of Intellectual Disability Research, Volume 70, Issue 4, Page 440-445, April 2026.
ABSTRACT Background Rare genetic variation can predispose individuals to the development of schizophrenia, with certain genes and copy number variants (CNVs) conferring risk at the exome/genome‐wide level. Despite this strong association, little is known about antipsychotic effectiveness and tolerability among individuals with most of these disorders ...
Mark Ainsley Colijn
wiley   +1 more source

The Differential Diagnosis of Coma in the ICU: Hyperacute Postoperative Guillain‐Barré Syndrome—A Case Report

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Guillain‐Barré syndrome (GBS) is a rare, immune‐mediated neurological disorder that can be challenging to diagnose in postoperative patients due to atypical manifestations and overlapping conditions. This case report highlights the diagnostic and therapeutic challenges of GBS following vascular surgery. We present the case of a 56‐year‐old man
Miron Tiganas, Abdulrahman Ismaiel, Dan Sebastian Dirzu, Iris Aszalos   +3 more
wiley   +1 more source

Atypical Antipsychotics

Der Nervenarzt, 2000
M, Heeringa, A C, van Grootheest
  +8 more sources

Huntington's Disease and Huntington's Disease‐like 2 (HDL2) in Martinique

Movement Disorders Clinical Practice, Volume 13, Issue 3, Page 673-682, March 2026.
ABSTRACT Background Huntington's Disease‐like 2 (HDL2), caused by a CAG repeat expansion in JPH3, closely resembles HD. All reported HDL2 patients to date have some African ancestry. While both disorders exist in the Caribbean, their relative frequency and clinical characteristics remain largely unknown.
Ignacio Antolin‐Sanfeliz, Anna‐Gaelle Giguet‐Valard, Sophie Duclos, Cécile Cazeneuve, Chloé Angelini, Aïssatou Signaté, Russell L. Margolis, Cyril Goizet, Rémi Bellance   +8 more
wiley   +1 more source

Efficacy and safety of atypical antipsychotic drugs (quetiapine, risperidone, aripiprazole and paliperidone) compared with placebo or typical antipsychotic drugs for treating refractory schizophrenia: overview of systematic reviews

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: According to some cohort studies, the prevalence of refractory schizophrenia (RS) is 20-40%. Our aim was to evaluate the effectiveness and safety of aripiprazole, paliperidone, quetiapine and risperidone for treating RS.
Tamara Melnik, Bernardo Garcia Soares, Maria Eduarda dos Santos Puga, Álvaro Nagib Atallah   +3 more
doaj   +1 more source

Risk factors for pneumonia in patients with schizophrenia

Neuropsychopharmacology Reports, 2018
Aim Pneumonia is a major cause of death in patients with schizophrenia. Preventive strategies based on identifying the risk factors are needed to reduce pneumonia‐related mortality.
Takahiro Haga, Kae Ito, Kentaro Sakashita, Mari Iguchi, Masahiro Ono, Koichiro Tatsumi   +5 more
doaj   +1 more source

Long‐Term Follow‐Up of Patients with Mass Social Media‐Induced Illness Presenting with Functional Tic‐like Behaviors

Movement Disorders Clinical Practice, Volume 13, Issue 3, Page 737-747, March 2026.
Abstract Background Only little is known about the prognosis of functional tic‐like behaviors (FTLB), especially in the subgroup of patients with mass social media‐induced illness (MSMI‐FTLB). Objectives To provide data of long‐term follow‐up (FU) of a carefully characterized group of patients with MSMI‐FTLB to identify influencing factors such as ...
L. Kathrin Hartung, Simon Schmitt, Carolin Fremer, Carolin S. Klages, Natalia Szejko, Kirsten R. Müller‐Vahl   +5 more
wiley   +1 more source

Ocular Motor Abnormalities in Functional Neurological Disorder: A Video‐Oculography Study

Movement Disorders Clinical Practice, Volume 13, Issue 3, Page 711-722, March 2026.
Abstract Background Functional neurological disorders (FND) can include various sensory, motor or cognitive symptoms. Eye movement recordings, measured through video‐oculography, could serve as biomarkers for characterizing these dysfunctions in FND.
Aude Sangare, Astrid de Liège, Bertrand Gaymard, Sophie Rivaud‐Péchoux, Cécilia Bonnet, Evžen Růžička, Jaromír May, Tereza Serranová, Francine Mesrati, Emmanuel Roze, Marie Vidailhet, Céline Louapre, Lionel Naccache, Béatrice Garcin   +13 more
wiley   +1 more source