Results 71 to 80 of about 52,048 (217)

Severe tardive dystonia on low dose short duration exposure to atypical antipsychotics: Factors explored

Indian Journal of Psychological Medicine, 2017
Tardive dystonia (TD) is a serious side effect of antipsychotic medications, more with typical antipsychotics, that is potentially irreversible in affected patients. Studies show that newer atypical antipsychotics have a lower risk of TD.
Nilanjan C Chandra, Shabina A Sheth, Ritambhara Y Mehta, Kamlesh R Dave   +3 more
doaj   +1 more source

Bipolar Disorder as a Long‐Term Risk Factor for Parkinson's Disease: A Nationwide Case–Control Study

Movement Disorders, EarlyView.
Abstract Background Previous studies suggest an association between bipolar disorder (BD) and an increased risk of Parkinson's disease (PD), but the long‐term temporal relationship remains unclear. Particularly, it is unclear whether the risk of PD is influenced by the duration since BD diagnosis.
Elina Jaakkola, Marjaana Koponen, Valtteri Kaasinen, Jarmo Hietala, Sirpa Hartikainen, Anna‐Maija Tolppanen   +5 more
wiley   +1 more source

The impact of atypical antipsychotics on the development of type 2 diabetes mellitus

Клинический разбор в общей медицине
Atypical antipsychotics (novell atypical generation antipsychotics) have entered clinical practice recently, but despite this, they have already managed to occupy one of the leading positions in modern therapy of mental disorders such as schizophrenia ...
Sabina E. Kurtmambetova, Yana V. Andrukh, Ruslan E. Kurtmambetov, Elena N. Primysheva, Irina N. Repinskaya   +4 more
doaj   +1 more source

Lifetime Mixed Depression and Childhood Trauma in Individuals With Bipolar Disorders

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Background and Aims Mixed Depression (MxD), characterized by the co‐occurrence of depressive and excitatory symptoms, is a prevalent yet often underdiagnosed presentation in bipolar disorders (BD), with significant implications for prognosis and treatment. Childhood trauma is a key environmental risk factor associated with a more severe course
Francesca Bardi, Mario Pinto, Alessio Simonetti, Marco Di Nicola, Marianna Mazza, Giovanni Manfredi, Georgios D. Kotzalidis, Gabriele Sani, Delfina Janiri   +8 more
wiley   +1 more source

Constrictive Pericarditis Associated with Atypical Antipsychotics

Case Reports in Cardiology, 2012
We report the successful surgical intervention in a case of constrictive pericarditis after long-term use of atypical antipsychotics. Pericarditis developed in our patient with a longstanding history of schizophrenia treated with atypical antipsychotics.
Kuan-chin Jean Chen, Aashish Goela, Patrick Teefy, L. Ray Guo   +3 more
doaj   +1 more source

Dosing strategies for switching from oral risperidone to paliperidone palmitate: Effects on clinical outcomes. [PDF]

, 2017
IntroductionThere are currently no guidelines for switching patients from oral risperidone to paliperidone palmitate (Invega Sustenna®). Furthermore, the paliperidone long-acting injectable (LAI) package insert does not recommend bridging with oral ...
Hsia, Stephanie L, Jackson, Elizabeth, Lacro, Jonathan P, Leckband, Susan G, Rao, Sanjai   +4 more
core   +2 more sources

Developing a Trauma Checklist for People With a Learning Disability Accessing Community Health and Support Services

British Journal of Learning Disabilities, EarlyView.
ABSTRACT Background Research suggests people with a learning disability experience high prevalence of adverse life events which may result in trauma‐related mental health conditions. Identifying trauma‐related mental health conditions can facilitate access to support, however research suggests they may be under‐identified in this group. The aim of this
Sarah Wigham, Arman Iranpour, John L. Taylor, Claire Hills‐Wilson, Pamela Reitemeier, Katharine Petersen, Iain McKinnon, Simon S. Hackett   +7 more
wiley   +1 more source

Atypical Antipsychotics and Other Therapeutic Options for Treatment of Resistant Major Depressive Disorder

Pharmaceuticals, 2010
Antidepressant therapies, such as selective serotonin reuptake inhibitors (SSRIs), are current first-line treatments for Major Depressive Disorder. However, over 50% of treated patients show an inadequate response to initial antidepressant therapy.
Allan H. Young, Holly MacPherson, Rubo J. Seo   +2 more
doaj   +1 more source

The phytocannabinoid, Δ(9) -tetrahydrocannabivarin, can act through 5-HT1 A receptors to produce antipsychotic effects [PDF]

, 2015
Funded by: •GW Pharmaceuticals Acknowledgements: The authors wish to thank Mrs Lesley Stevenson for technical support and Dr John Raymond, Dr Keith Parker and Dr Ethan Russo for providing human 5-HT1A CHO cells.
Cascio, Maria Grazia, Marini, Pietro, Parolaro, Daniela, Pertwee, Roger G., Zamberletti, Erica   +4 more
core   +1 more source

Evaluation of preclinical antipsychotic models used to support first‐in‐human clinical trials

British Journal of Pharmacology, EarlyView.
Abstract Schizophrenia is regarded as a complex and heterogeneous psychiatric disorder, characterised by diverse symptoms and comorbidities, which complicate both clinical management and drug development. Current pharmacological treatment, primarily based on dopamine D2 receptor antagonism or partial agonism, which has not markedly progressed since the
Thi Viet Ha Nguyen, Declan P. McKernan, John P. Kelly   +2 more
wiley   +1 more source