Results 81 to 90 of about 23,004 (191)

Safety of Vortioxetine in Patients With Depression: A Post‐Marketing Surveillance Study of Intracranial Hemorrhage in a Japanese Health Insurance Claims Database

Neuropsychopharmacology Reports, Volume 46, Issue 1, March 2026.
This real‐world, retrospective cohort study showed that the incidence of intracranial hemorrhage was low in Japanese patients with depression prescribed vortioxetine, and comparable with that observed in patients prescribed selective serotonin reuptake inhibitors (SSRIs).
Takeshi Inoue, Rie Otake, Tatsuya Hoshino   +2 more
wiley   +1 more source

Evaluating and Determining the Effects of Psychotropic Drugs on Motor Vehicle Driving Performance: Key Considerations of the Japanese Guideline and Criteria for Clinical Implementation of Evidence

Neuropsychopharmacology Reports, Volume 46, Issue 1, March 2026.
The Japanese guideline and criteria for evaluating and determining the effects of psychotropic drugs on motor vehicle driving performance enable the clinical implementation of evidence by assessing “persistence of clinically meaningful impairment”. ABSTRACT The cross‐national differences in automobile driving precautions stated in psychotropic drug ...
Tetsuo Nakabayashi, Kunihiro Iwamoto, Akiko Yamaguchi, Yuki Konishi, Momoe Saji, Reiji Yoshimura, Kousuke Kanemoto, Hirofumi Aoki, Masahiko Ando, Norio Ozaki   +9 more
wiley   +1 more source

Catatonia an Unexpected Side Effect of Electroconvulsive Therapy: A Case Report

Neuropsychopharmacology Reports, Volume 46, Issue 1, March 2026.
This case report highlights an unexpected development of catatonia following electroconvulsive therapy in a patient with schizoaffective disorder. The catatonia resolved promptly after discontinuing psychotropic interventions, emphasizing the need for careful monitoring during ECT, especially in patients with complex psychiatric histories.
Fatemeh sheikhmoonesi, Behnam Abbasi, Tahoura Sedighi Barforoushi, Ebrahim Khoshnama   +3 more
wiley   +1 more source

The risk of bone fracture after long-term risperidone exposure is not increased compared to other atypical antipsychotics: A retrospective cohort study.

PLoS ONE, 2019
ObjectiveAntipsychotic agents can increase circulating serum prolactin levels, potentially leading to osteoporosis and increased risk of bone fracture. The risk appears to be lower for atypical antipsychotics.
Shih-Pei Shen, Yanfang Liu, Hong Qiu, Kuan-Yi Tsai, Hung-Chi Wu, Wen-Miin Liang, Meng Shu, Frank Huang-Chih Chou   +7 more
doaj   +1 more source

Real‐World Pharmacological Management of Alcohol Dependence in a Nepalese Rehabilitation Center: Prospective Cohort Study

Public Health Challenges, Volume 5, Issue 1, March 2026.
This prospective cohort study demonstrates that structured, evidence‐informed pharmacological management significantly reduced alcohol withdrawal severity and improved liver enzyme profiles among alcohol dependence patients in a Nepalese rehabilitation center, supporting the implementation of standardized treatment protocols in resource‐limited ...
Sanjay Singh, Nirmal Raj Marasine, Sabina Sankhi, Kabita Bhandari, Gajendra Bahadur Bhuju   +4 more
wiley   +1 more source

Subchronic Exposure to Aripiprazole Subtly Impacts on Rodents' Sperm Quality and Fertility

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.
ABSTRACT Aripiprazole, a third‐generation antidepressant/antipsychotic drug, acts on serotonergic and dopaminergic receptors and is widely prescribed for mental disorders, such as depression and schizophrenia. Studies indicate that this class of drugs can impact directly on sperm quality and fertility.
Maria Joana Nogueira de Moura, Renata Gleysiane Sousa de Felix, Aline Gabriele Gomes da Silva, Ana Beatriz Silva Angelo, Caio César Araújo dos Santos, Artemia Kelly Holanda Pereira, Michelly Fernandes de Macedo, Cibele dos Santos dos Borges   +7 more
wiley   +1 more source

Understanding the Current State of Play of Early Intervention for Bipolar Disorder: Qualitative Analysis of Consultations With International Stakeholders

Bipolar Disorders, Volume 28, Issue 2, March 2026.
ABSTRACT Background Despite the burden associated with bipolar disorder (BD), research into early diagnosis and treatment of BD lags approximately 20 years behind the field of early intervention for psychosis. This study evolved through a partnership between Orygen (Melbourne, Australia) and the Daymark Foundation (Toronto, Canada).
Sue M. Cotton, Vani Jain, Aswin Ratheesh, Clare Shelton, Craig Macneil, Kate M. Filia, Jacob Crouse, Annabel Burnside, Emily Clarke, Alesha Prasad, Rosie Arnold, Paul Badcock, Melissa Hasty   +12 more
wiley   +1 more source

Developing a Trauma Checklist for People With a Learning Disability Accessing Community Health and Support Services

British Journal of Learning Disabilities, Volume 54, Issue 1, Page 74-84, March 2026.
ABSTRACT Background Research suggests people with a learning disability experience high prevalence of adverse life events which may result in trauma‐related mental health conditions. Identifying trauma‐related mental health conditions can facilitate access to support, however research suggests they may be under‐identified in this group. The aim of this
Sarah Wigham, Arman Iranpour, John L. Taylor, Claire Hills‐Wilson, Pamela Reitemeier, Katharine Petersen, Iain McKinnon, Simon S. Hackett   +7 more
wiley   +1 more source

Impact of CYP2D6 Genotype and Inhibitor Use on Risperidone Metabolism in Children: Functional Insights Into the *17 and *29 Alleles

Clinical and Translational Science, Volume 19, Issue 3, March 2026.
ABSTRACT Risperidone, an atypical antipsychotic, is increasingly prescribed in pediatric patients with psychiatric disorders. It is primarily metabolized by CYP2D6 to 9‐hydroxyrisperidone, an active metabolite associated with a higher risk of adverse effects.
Matthew H. Bennett, Ethan A. Poweleit, Samuel E. Vaughn, Brandon Retke, Paul Toren, Jeffrey R. Strawn, Laura B. Ramsey   +6 more
wiley   +1 more source

How copy number variations shape brain developmental disorders: Unraveling the synaptic puzzle

Psychiatry and Clinical Neurosciences, Volume 80, Issue 3, Page 166-179, March 2026.
Neurodevelopmental disorders (NDDs), such as schizophrenia (SCZ), Attention‐deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), learning disabilities, and intellectual disabilities (ID), are highly prevalent. One significant genetic factor associated with NDDs is copy number variations (CNVs), which are structural changes in the ...
Tianqi Wang, Kubra Trabzonlu, Emily Fullard Jones, Yasir Ahmed Syed   +3 more
wiley   +1 more source