Results 41 to 50 of about 192,417 (163)

Novel assay with fluorescence‐labelled PrP peptides for differentiating L‐type atypical and classical BSEs, and scrapie [PDF]

open access: yesFEBS Letters, 2012
PrP‐peptides HPP01, 02, 03, 06, 11 physically interact with PrPScof L‐type atypical and classical BSEs, and scrapie by pull ...
Kasai, Kazuo   +5 more
openaire   +2 more sources

Biochemical typing of pathological prion protein in aging cattle with BSE

open access: yesVirology Journal, 2009
Background The broad enforcement of active surveillance for bovine spongiform encephalopathy (BSE) in 2000 led to the discovery of previously unnoticed, atypical BSE phenotypes in aged cattle that differed from classical BSE (C-type) in biochemical ...
Leeb Tosso   +8 more
doaj   +1 more source

Spatial analysis of BSE cases in the Netherlands [PDF]

open access: yes, 2008
Background In many of the European countries affected by Bovine Spongiform Encephalopathy (BSE), case clustering patterns have been observed. Most of these patterns have been interpreted in terms of heterogeneities in exposure of cattle to the BSE agent.
Thomas J Hagenaars   +8 more
core   +1 more source

Molecular, biochemical and genetic characteristics of BSE in Canada.

open access: yesPLoS ONE, 2010
The epidemiology and possibly the etiology of bovine spongiform encephalopathy (BSE) have recently been recognized to be heterogeneous. In particular, three types [classical (C) and two atypical (H, L)] have been identified, largely on the basis of ...
Sandor Dudas   +6 more
doaj   +1 more source

State-of-the-art review of goat TSE in the European Union, with special emphasis on PRNP genetics and epidemiology [PDF]

open access: yes, 2009
Scrapie is a fatal, neurodegenerative disease of sheep and goats. It is also the earliest known member in the family of diseases classified as transmissible spongiform encephalopathies (TSE) or prion diseases, which includes Creutzfeldt-Jakob disease in ...
Olivier Andreéoletti   +54 more
core   +1 more source

Atypical Scrapie Prions from Sheep and Lack of Disease in Transgenic Mice Overexpressing Human Prion Protein

open access: yesEmerging Infectious Diseases, 2013
Public and animal health controls to limit human exposure to animal prions are focused on bovine spongiform encephalopathy (BSE), but other prion strains in ruminants may also have zoonotic potential.
Jonathan D.F. Wadsworth   +11 more
doaj   +1 more source

Intraspecies transmission of BASE induces clinical dullness and amyotrophic changes. [PDF]

open access: yesPLoS Pathogens, 2008
The disease phenotype of bovine spongiform encephalopathy (BSE) and the molecular/ biological properties of its prion strain, including the host range and the characteristics of BSE-related disorders, have been extensively studied since its discovery in ...
Guerino Lombardi   +17 more
doaj   +1 more source

Experimental H-type and L-type bovine spongiform encephalopathy in cattle: observation of two clinical syndromes and diagnostic challenges

open access: yesBMC Veterinary Research, 2012
Background The majority of atypical bovine spongiform encephalopathy (BSE) cases so far identified worldwide have been detected by active surveillance.
Konold Timm   +6 more
doaj   +1 more source

A sequencing strategy for identifying variation throughout the prion gene of BSE-affected cattle

open access: yesBMC Research Notes, 2008
Background Classical and atypical bovine spongiform encephalopathies (BSEs) are cattle prion diseases. Distinct bovine prion gene (PRNP) alleles have been associated with classical and atypical BSE susceptibility.
Harhay Gregory P   +6 more
doaj   +1 more source

RT-QuIC detection of pathological prion protein in subclinical goats following experimental oral transmission of L-type BSE

open access: yesBMC Research Notes, 2021
Objective The spread of bovine spongiform encephalopathy (BSE) agent to small ruminants is still a major issue in the surveillance of transmissible spongiform encephalopathies (TSEs). L-type bovine spongiform encephalopathy (L-BSE) is an atypical form of
Alessandra Favole   +17 more
doaj   +1 more source

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