Results 121 to 130 of about 13,547 (264)

Quantitative analysis of the potential role of basal cell hyperplasia in the relationship between clonal expansion and radon concentration [PDF]

arXiv, 2018
Applying the two-stage clonal expansion model to epidemiology of lung cancer among uranium miners, it has been revealed that radon acts as a promoting agent facilitating the clonal expansion of already mutated cells. Clonal expansion rate increases non-linearly by radon concentration showing a plateau above a given exposure rate.
arxiv  

Can thyroid histomorphology identify patients with PTEN hamartoma tumour syndrome?

Histopathology, Volume 85, Issue 6, Page 929-938, December 2024.
Multiple histologic features of thyroid follicular nodular disease are found frequently in patients with PTEN Hamartoma Tumour Syndrome. In this study we propose an exploratory Thyroid Histomorphologic PHTS Score system. Aims The phosphatase and tensin homologue (PTEN) hamartoma tumour syndrome (PHTS) is a genetic disorder with variable clinical ...
Melad N Dababneh, Laura Rabinowitz, Gilman Plitt, Charis Eng, Christopher C Griffith   +4 more
wiley   +1 more source

Expression of the VEGF marker in endometrial cells in hyperplastic processes

Journal of Education, Health and Sport, 2020
Hormone-dependent diseases related to preproliferative processes and endometrial cancer have a clear tendency to increase and rejuvenate. The purpose: to study the expression of VEGF marker in endometrial cells under physiological, hyperplastic, atypical
Z. V. Chumak
doaj   +1 more source

Endometrial study in patients with postmenopausal metrorrhagia [PDF]

, 2016
Introduction: The aim of the study was to devise a strategy to diagnose malign endometrial pathologies (adenocarcinoma or atypical hyperplasia) that minimizes the number of invasive tests done (hysteroscopy, aspiration biopsy or curettage) with no loss ...
González de Merlo, Gaspar, González Mirasol, Esteban, Gómez García, María Teresa, Iglesias Goy, Enrique, Serna Torrijos, María C., Ángel Parra, Carmen   +5 more
core   +6 more sources

SHP2‐Triggered Endothelial Cell Activation Fuels Estradiol‐Independent Endometrial Sterile Inflammation

Advanced Science, Volume 11, Issue 41, November 6, 2024.
SHP2 mediates the transition of endothelial activation from estradiol‐driven acute inflammation to macrophage‐amplified chronic inflammation. Activated endothelial cells interact with macrophages and epithelial cells to generate and sustain endometrial sterile inflammation, thus promoting endometrial hyperplasia by IGF1.
Jie Pan, Jiao Qu, Wen Fang, Lixin Zhao, Wei Zheng, Linhui Zhai, Minjia Tan, Qiang Xu, Qianming Du, Wen Lv, Yang Sun   +10 more
wiley   +1 more source

Computer morphometry: experience in the study of clinical value in endometrial precancer

Опухоли женской репродуктивной системы, 2014
The differential diagnosis of simple endometrial hyperplasia (SEH), complex endometrial hyperplasia (CEH), atypical endometrial hyper- plasia (AEH), and endometrial cancer (EC) is associated with a number of difficulties, frequently giving rise to ...
A. Kh. Bishtavi, O. A. Gornykh, A. A. Kanibolotsky, Yu. Yu. Tabakman, I. B. Manukhin   +4 more
doaj   +1 more source

A Multicenter Cohort Study on DNA Methylation for Endometrial Cancer Detection in Cervical Scrapings

Cancer Medicine, Volume 13, Issue 21, November 2024.
ABSTRACT Background The increasing incidence of endometrial cancer (EC) has highlighted the need for improved early detection methods. This study aimed to develop and validate a novel DNA methylation classifier, EMPap, for EC detection using cervical scrapings.
Xiao Ma, Xiaojun Chen, Jing Liang, Jingbo Zhang, Qixi Wu, Dong Wang, Xianghua Huang, Dan Zi, Dexin Chen, Hua Wan, Li Qu, Zhaoyun Jiang, Wenyu Shao, Jie Sun, Luyuan Chang, Yunchao Liu, Qin Zhang, Yanan Li, Yani Ding, Biao Tang, Fang Zhao, Hanqing Zhao, Dongyan Cao   +22 more
wiley   +1 more source

The utility of next‐generation sequencing in challenging liver FNA biopsies

Cancer Cytopathology, Volume 132, Issue 11, Page 714-722, November 2024.
Abstract Background Fine‐needle aspiration (FNA) biopsy is increasingly used for the diagnosis of hepatocellular masses. Because distinguishing well differentiated hepatocellular carcinoma (HCC) from other well differentiated hepatocellular lesions (e.g., large regenerative nodules or focal nodular hyperplasia) requires an assessment of architectural ...
Dana J. Balitzer, Nancy Y. Greenland
wiley   +1 more source

Differentiation between endometrial carcinoma and atypical endometrial hyperplasia with transvaginal sonographic elastography

Diagnostic and Interventional Imaging, 2016
To assess the value of transvaginal sonographic elastography (TSE) in discriminating between endometrial hyperplasia and endometrial carcinoma.A total of 61 women with post-menopausal hemorrhage and/or normal TSE were included. There were 32 women (mean age: 53.1±14.1 years) with endometrial hyperplasia, 14 women (mean age: 60.0±14.0 years) with ...
Avcu, SERHAT, Unal, O., AKÇAY, YASEMİN, Turkyilmaz, E., Metin, M. R., Duymus, M., Aydin, H.   +6 more
openaire   +4 more sources

Молекулярно-генетические характеристики пациенток с гиперплазией и полипами эндометрия [PDF]

, 2018
Гиперпластические процессы эндометрия (ГПЭ) являются одними из наиболее частых гинекологических заболеваний, приводят к потере репродуктивной функции и снижению качества жизни женщин, являются основой для формирования злокачественных опухолей эндометрия.
Демакова, Н. А.
core   +2 more sources