Prevalence of Co-existing Endometrial Carcinoma in Patients with Preoperative Diagnosis of Endometrial Hyperplasia [PDF]
Introduction: Endometrial hyperplasia has been associated with the presence of concomitant endometrial carcinoma. In this study, patients who were diagnosed with endometrial hyperplasia and had hysterectomy, determination of the incidence of ...
Pinar Kadirogullari +3 more
doaj +1 more source
p21-Activated Kinases 1, 2 and 4 in Endometrial Cancers: Effects on Clinical Outcomes and Cell Proliferation [PDF]
p21-activated kinases (Paks) are serine/threonine protein kinases involved in biological events linked to malignant tumor progression. In this study, expression of Pak1, p-Pak2 Ser20, Pak4, pPak4 Ser474 in 21 normal endometrium, 16 hyperplastic ...
Chan, HY +9 more
core +1 more source
Metformin as a Therapeutic Target in Endometrial Cancers. [PDF]
Endometrial cancer is the most common gynecologic malignancy in developed countries. Its increasing incidence is thought to be related in part to the rise of metabolic syndrome, which has been shown to be a risk factor for the development of ...
Johnson, Jennifer +6 more
core +2 more sources
Invasive Endometrial Cancer in Uteri Resected for Atypical Endometrial Hyperplasia
Endometrial hyperplasia (EH) includes a spectrum of lesions with unclear malignant potential. To examine the association between the most advanced forms of hyperplasia and the occurrence of endometrial cancer, we compared the findings of endometrial biopsies or curettings with the subsequent hysterectomy specimens in 44 women who underwent hysterectomy
M F, Janicek, N B, Rosenshein
openaire +2 more sources
Annual outpatient hysteroscopy and endometrial sampling (OHES) in HNPCC/Lynch syndrome (LS) [PDF]
Background: LS women have a 40-60 % lifetime risk of endometrial cancer (EC). Most international guidelines recommend screening. However, data on efficacy are limited.
Adam N. Rosenthal +43 more
core +1 more source
Diabetes Mellitus Is Associated with Occult Cancer in Endometrial Hyperplasia [PDF]
In the management of women diagnosed with endometrial hyperplasia (EH), it is crucial to determine the risk of coexistent cancer. Diabetes mellitus has been recently suggested as a significant risk factor. However, results in this regard are conflicting.
Arduino, B. +8 more
core +1 more source
DNA methylation of selected tumor suppressor genes in endometrial hyperplasia
Aims. To investigate DNA methylation of specific gene promoters in endometrial hyperplasia compared to normal endometrial tissue. Materials and Methods.
Ondrej Dvorak +4 more
doaj +1 more source
ObjectiveTo evaluate the effect of maintenance therapy for patients with atypical endometrial hyperplasia (AEH) and early endometrial cancer (EC) after successful fertility-preserving management on prognosis and pregnancy outcome.MethodsWe performed a ...
Yijiao He +10 more
doaj +1 more source
An integrated care pathway for menorrhagia across the primary–secondary interface : patients' experience, clinical outcomes, and service utilisation [PDF]
Background: ‘‘Referral’’ characterises a significant area of interaction between primary and secondary care. Despite advantages, it can be inflexible, and may lead to duplication.
Baker, Richard +7 more
core +2 more sources
Анализа на етиолошки фактори за појава на ендометријална хиперплазија во перименопаузa [PDF]
The aim of this study was to evaluate the possible reasons for the emergence of endometrial hyperplasia in perimenopause. Material and methods: A total of 71 patients with irregular bleeding were analyzed, at the age of 40-50 years, who should have ...
Arsovska, Anita +4 more
core +2 more sources

