Results 31 to 40 of about 6,797 (180)

DNA methylation of selected tumor suppressor genes in endometrial hyperplasia

open access: yesBiomedical Papers
Aims. To investigate DNA methylation of specific gene promoters in endometrial hyperplasia compared to normal endometrial tissue. Materials and Methods.
Ondrej Dvorak   +4 more
doaj   +1 more source

Expression of the VEGF and angiopoietin genes in endometrial atypical hyperplasia and endometrial cancer [PDF]

open access: yesBritish Journal of Cancer, 2003
Angiogenesis is critical for the growth and metastasis of endometrial cancer and is therefore an important therapeutic target. Vascular endothelial growth factor-A (VEGF-A) is a key molecule in angiogenesis, but the identification of related molecules and the angiopoietins suggests a more complex picture. We investigated the presence of transcripts for
Holland, Catherine   +4 more
openaire   +3 more sources

Does Preoperative Diagnosis of Endometrial Hyperplasia Necessitate Intraoperative Frozen Section Consultation?

open access: yesBalkan Medical Journal, 2016
Background: In women with endometrial hyperplasia, there is a risk for co-existent endometrial cancer when patients are subjected to immediate surgical treatment.
Gokhan Boyraz   +4 more
doaj   +1 more source

Retrospective analysis of outcome after endometrial ablation with the NovaSure device: A German single‐center experience

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Evaluation of retrospective outcomes of NovaSure treatment in patients with abnormal uterine bleeding, including safety and cost‐effectiveness, and risk factors related to therapeutic outcomes. Subgroup analysis was conducted for patients who underwent concomitant surgical procedures, required subsequent interventions, and were ...
Oliver M. Schleicher   +8 more
wiley   +1 more source

Клініко-генеалогічне дослідження хворих на гіперплазію і рак ендометрію Київського регіону

open access: yesФактори експериментальної еволюції організмів, 2017
Aim. To determine the informativeness of genealogical and morphological characteristics of patients with endometrial hyperplasia and cancer. Methods.
L. G. Buchynska   +3 more
doaj   +1 more source

Maintenance Therapy Can Improve the Oncologic Prognosis and Obstetrical Outcome of Patients With Atypical Endometrial Hyperplasia and Endometrial Cancer After Fertility-Preserving Treatment: A Multicenter Retrospective Study

open access: yesFrontiers in Oncology, 2021
ObjectiveTo evaluate the effect of maintenance therapy for patients with atypical endometrial hyperplasia (AEH) and early endometrial cancer (EC) after successful fertility-preserving management on prognosis and pregnancy outcome.MethodsWe performed a ...
Yijiao He   +10 more
doaj   +1 more source

Pelvic Ultrasound for Predicting Endometrial Neoplasia in Premenopausal Abnormal Uterine Bleeding

open access: yesJournal of Ultrasound in Medicine, EarlyView.
Objectives Although ultrasound is the first line imaging modality for abnormal uterine bleeding (AUB), there is a lack of consensus on its predictiveness for premenopausal endometrial pathology. This study aims to determine the predictiveness of pelvic ultrasound for endometrial neoplasia and cancer precursor lesions in premenopausal patients ...
Jessica Grubman   +7 more
wiley   +1 more source

Endometrial Atypical Hyperplasia and Risk of Endometrial Cancer

open access: yesDiagnostics
Endometrial atypical hyperplasia (EAH) is a premalignant condition with a substantial risk of progression to endometrial cancer (EC), with the endometrioid subtype being the most common. EAH is characterized by abnormal endometrial gland proliferation and cellular atypia, often resulting from prolonged unopposed estrogen exposure.
An-Ju Chou, Ruo-Shi Bing, Dah-Ching Ding
openaire   +3 more sources

A Multicellular Coordinated Network Driving Lymphovascular Space Invasion in Endometrioid Endometrial Carcinoma

open access: yesCell Proliferation, EarlyView.
Single‐cell and spatial profiling reveal that lymphovascular space invasion in endometrioid endometrial carcinoma is driven by coordinated interactions among metastatic epithelium, fibroblasts, immune cells, and endothelium. This multicellular network promotes matrix remodelling, angiogenesis, and immune evasion, forming a pro‐metastatic niche that ...
Wendi Guo   +7 more
wiley   +1 more source

The Expression and Clinical Significance of Sphingosine Kinase 1 and Vascular Endothelial Growth Factor in Endometrial Carcinoma

open access: yesEmergency Medicine International, 2022
The aim of the study is to investigate the expression of sphingosine kinase 1 (SPHK1) and vascular endothelial growth factor (VEGF) in patients with endometrial carcinoma and its clinical significance. The tissues of 86 cases of patients with endometrial
Hong Yu   +6 more
doaj   +1 more source

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