Results 61 to 70 of about 12,572 (210)

Diagnostic accuracy of hysteroscopy vs dilation and curettage (D&C) for atypical endometrial hyperplasia in patients performing hysterectomy or serial follow-up

Clinical and Experimental Obstetrics & Gynecology, 2022
Background: Endometrial hyperplasia (EH) is considered a heterogeneous pre-neoplastic clinical entity characterized by an abnormal glandular proliferation, with less than half of the tissue area occupied by the stroma. The aim of this retrospective study
Luigi Nappi, Stefano Angioni, Vincenzo De Feo, Pantaleo Greco, Guglielmo Stabile, Francesca Greco, Maurizio Nicola D'Alterio, Felice Sorrentino   +7 more
doaj   +1 more source

Молекулярно-генетические характеристики пациенток с гиперплазией и полипами эндометрия [PDF]

, 2018
Гиперпластические процессы эндометрия (ГПЭ) являются одними из наиболее частых гинекологических заболеваний, приводят к потере репродуктивной функции и снижению качества жизни женщин, являются основой для формирования злокачественных опухолей эндометрия.
Демакова, Н. А.
core   +2 more sources

Mixed Gonadal Dysgenesis: A Comprehensive Review of Clinical Spectrum, Diagnostic Strategies, and Management Approaches

Clinical Endocrinology, Volume 104, Issue 2, Page 92-102, February 2026.
ABSTRACT Background Mixed gonadal dysgenesis (MGD) is a rare form of differences in sex development (DSD) typically associated with 45,X/46,XY mosaicism. The phenotypic presentation of MGD varies from atypical genitalia to typical male or female appearances often associated with Turner stigmata.
Dinesh Giri, Sushil Yewale, Hannah Hickingbotham, Cara Williams, Mohamed Shalaby, Julie Alderson, Julie Park   +6 more
wiley   +1 more source

Malignant transformation of endometrial hyperplastic processes: immunohistochemical features

Опухоли женской репродуктивной системы, 2022
Background. Endometrial hyperplasia is one of the most common pathologies of the female reproductive system. There is a high risk of transformation of an atypical form of endometrial hyperplasia into endometrial cancer, which takes a leading position in ...
M. S. Sobivchak, A. E.  Protasova, G. A. Raskin, M. S. Mukhina, A. S. Kaurtseva   +4 more
doaj   +1 more source

Histopathology Images‐Based Deep Learning Prediction of Histological Types in Endometrial Cancer

Cancer Medicine, Volume 15, Issue 1, January 2026.
ABSTRACT Background According to the new 2023 International Federation of Gynecology and Obstetrics staging system for endometrial cancer (EC), EC is classified into aggressive and nonaggressive histological types. Accurate diagnosis of the histological type of EC is crucial for optimizing treatment strategies and predicting patient outcomes ...
Lingmei Li, Pengbo Wang, Changyu Geng, Jingyi Wang, Lu Cao, Yanan Gao, Dandan Chen, Ge Qiao, Shi Zhang, Ningrui Feng, Ming Liu, Xiaofeng Li, Yaomei Ma, Su Zhang, Huiting Xiao, Zhongmin Jiang, Xiaozhi Liu, Wenjuan Ma, Lisha Qi   +18 more
wiley   +1 more source

Evaluation of coagulation disorders and iron deficiency in women with heavy menstrual bleeding

International Journal of Gynecology &Obstetrics, Volume 172, Issue 1, Page 250-254, January 2026.
Abstract Objective To explore the incidence of congenital bleeding disorders (CBD), which may result in anemia, in a large cohort of women referred for heavy menstrual bleeding (HMB) in a specialized gynecologic unit. Methods Between January 2022 and January 2024, all women referred for HMB were screened.
Lucia Rugeri, Yelena Fruchou, Caroline Brodbeck, Marianne Bastien, Amandine Lioux, Giulia Gouy, Marion Cortet, Gil Dubernard, Yesim Dargaud   +8 more
wiley   +1 more source

Significant risk of occult cancer in complex non-atypical endometrial hyperplasia [PDF]

, 2019
BACKGROUND: In the 2014 WHO classification of endometrial hyperplasia (EH), complex EH is lumped together with simple EH in the benign category of non-atypical EH.
Arduino, B., D'Alessandro, P., de Placido, G., Insabato, L., Mascolo, M., Raffone, A., Saccone, G., Travaglino, A., Zullo, F.   +8 more
core   +1 more source

Breast Cancer: Molecular Pathogenesis, Targeted Therapy, Screening, and Prevention

MedComm, Volume 7, Issue 1, January 2026.
The review manuscript examines the molecular pathogenesis, screening, prevention advances, and evolving targeted therapies in breast cancer. It highlights the integration of AI and multiomics for precision prevention and personalized treatment, pointing toward future directions in equitable cancer care.
Huijun Lei, Jinzhen Fu, Wei Gu, Hongjin Qiao, Huixue Guo, Zijian Chen, San Ming Wang, Tianhui Chen   +7 more
wiley   +1 more source

Digital Morphometry of Cytologic Aspirate Endometrial Samples [PDF]

, 2010
Unlike cervical cytology, morphological cytology criteria in the differential diagnosis of endometrium have not yet been clearly defined, and methods to allow for more precise evaluation of endometrium status have been searched for.
Ana Barišić, Ana Ovanin-Rakić, Damir Babić, Danijela Jurič, Ivana Šamija Projić, Jadranka Božikov, Jadranka Ilić-Forko, Lada Škopljanac-Mačina, Sanda Rajhvajn, Snježana Škrablin-Kučić, Vesna Mahovlić   +10 more
core   +1 more source

Fos co-operation with PTEN loss elicits keratoacanthoma not carcinoma due to p53/p21^WAF-induced differentiation triggered by GSK3b inactivation and reduced AKT activity [PDF]

, 2008
To investigate gene synergism in multistage skin carcinogenesis, the RU486-inducible cre/lox system was employed to ablate PTEN function [K14.cre/D5PTENflx] in mouse epidermis expressing activated v-fos [HK1.fos].
Alexander, C.L., Chan, W-C., Greenhalgh, D.A., Quinn, J., Wu, H., Yao, D.   +5 more
core   +1 more source