Results 111 to 120 of about 24,893 (251)

Eculizumab safely reverses neurologic impairment and eliminates need for dialysis in severe atypical hemolytic uremic syndrome

open access: yesClinical Pharmacology: Advances and Applications, 2011
Maro Ohanian, Christian Cable, Kathleen HalkaDepartment of Hematology and Oncology, Scott and White Healthcare, The Texas A&M Health Science Center College of Medicine, Temple, TX, USAAbstract: This case report describes how eculizumab reversed ...
Ohanian M, Cable CC, Halka KK
doaj  

Atypical haemolytic-uraemic syndrome caused by factor H mutation: case report and new management strategies in children [PDF]

open access: yes, 2012
Atypical haemolytic uraemic syndrome is causedby alternative complement pathway dysregulation. It has recently been recognised that most cases are due to genetic factors and a growing list of mutations has been described.
Araújo, L.   +5 more
core  

Properdin and factor H: Opposing players on the alternative complement pathway "see-saw" [PDF]

open access: yes, 2013
This article has been made available through the Brunel Open Access Publishing Fund.Properdin and factor H are two key regulatory proteins having opposite functions in the alternative complement pathway.
Abdul-Aziz, M   +5 more
core   +1 more source

Differential complement activation by alloantibodies in sickle cell hyperhaemolysis syndrome may influence disease course

open access: yes
British Journal of Haematology, EarlyView.
Mamie M. Thant   +4 more
wiley   +1 more source

Complete Dialysis‐Free Recovery From Severe Malaria–Associated Acute Kidney Injury and Multiorgan Failure: A Case Report and Brief Literature Review

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Severe malaria remains a major cause of acute kidney injury and multiorgan failure in endemic regions, often requiring renal replacement therapy. However, access to dialysis is limited in many resource‐constrained settings, making outcomes highly dependent on early diagnosis and effective antimalarial treatment. We report a 32‐year‐old man who
Tamirat Godebo Woyimo   +8 more
wiley   +1 more source

SUCCESSFUL TREATMENT FOR ATYPICAL HEMOLYTIC UREMIC SYNDROME IN A PUERPERA

open access: yesОбщая реаниматология, 2016
Objective: to show the problems of differential diagnosis and treatment of atypical hemolytic-uremic syndrome in a 23-year-old patient.Results. Eculizumab (Soliris), (Alexon Pharmaceuticals Inc., USA) that is a glycosylated humanized monoclonal antibody ...
O. N. Ulitkina   +4 more
doaj   +1 more source

Thrombomodulin enhances complement regulation through strong affinity interactions with factor H and C3b-Factor H complex [PDF]

open access: yes, 2016
Introduction Coagulation and complement systems are simultaneously activated at sites of tissue injury, leading to thrombin generation and opsonisation with C3b.
Baerga-Ortiz   +58 more
core   +2 more sources

Exercise‐induced vasculitis with histological and genetic evidence of complement involvement

open access: yes
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Massimo Cugno   +6 more
wiley   +1 more source

Concurrent Scrub Typhus, Dengue, and Leptospirosis: A Rare Triple Co‐Infection: A Case Report and Comprehensive Literature Review

open access: yesClinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT In endemic areas, acute undifferentiated febrile illness has a wide differential with overlapping features that can lead to misdiagnosis. Although triple co‐infection with scrub typhus, dengue, and leptospirosis is extremely rare, high clinical suspicion and early detection are vital to avoid delayed treatment, multi‐organ dysfunction, and ...
Sulav Kumar Jha   +5 more
wiley   +1 more source

Intravascular Large B-Cell Lymphoma Presenting as Dementia and Hemolytic Anemia [PDF]

open access: yes, 2010
Background: Intravascular lymphoma (IVL) is an uncommon disease characterized by atypical lymphoid cells growing inside the lumina of small vessels. The diversity of clinical presentation due to possible involvement of multiple organs often complicates ...
Ahle, Guido   +6 more
core   +1 more source

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