Results 91 to 100 of about 1,333,557 (170)

Shigatoxin-associated hemolytic uremic syndrome: current molecular mechanisms and future therapies

, 2012
Lindsay S Keir,1 Stephen D Marks,2 Jon Jin Kim21Academic Renal Unit, University of Bristol, Bristol; 2Department of Paediatric Nephrology, Great Ormond Street Hospital NHS Foundation Trust, London, United KingdomAbstract: Hemolytic uremic syndrome is the
Marks SD, Kim JJ, Keir LS
core  

Pathogenic Variants in Complement Genes and Risk of Atypical Hemolytic Uremic Syndrome Relapse after Eculizumab Discontinuation

, 2016
International audienceBACKGROUND AND OBJECTIVES: The complement inhibitor eculizumab has dramatically improved the outcome of atypical hemolytic uremic syndrome.
Delmas, Yahsou, Cailliez, Mathilde, Rafat, Cédric, Karras, Alexandre, Chantal Loirat, Cédric Rafat, Delmas, Y., Valérie Châtelet, Hogan, Julien, Barbet, Christelle, Christelle Barbet, Chatelet, V., Loirat, C., Frémeaux-Bacchi, Véronique, Makdassi, Raifah, Servais, Aude, Véronique Frémeaux-Bacchi, Fila, Marc, François Provôt, Marc Fila, Coindre, J. P., Châtelet, Valérie, Rondeau, Eric, Provôt, François, Fila, M., Louillet, F., Cailliez, M., Karras, A., Provot, F., Julien Hogan, Feriell Louillet, Hogan, J., Mathilde Cailliez, Fakhouri, F., Yahsou Delmas, Alexandre Karras, Fakhouri, Fadi, Jean-Philippe Coindre, Loirat, Chantal, Raifah Makdassi, Rafat, C., Servais, A., Louillet, Feriell, Barbet, C., Fadi Fakhouri, Coindre, Jean-Philippe, Rondeau, E., Eric Rondeau, Fremeaux-Bacchi, V., Aude Servais, Makdassi, R.   +50 more
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Atypical hemolytic uremic syndrome in tertiary hospital, Pakistan

, 2016
Atypical hemolytic uremic syndrome (HUS) is a rare disorder in children, therefore it may lead to misdiagnosis, delay in treatment, or acute kidney injury.
Badruddin, Shirin, Rattani, Salma
core  

Complement mutations in Diacylglycerol Kinase-E-associated atypical hemolytic uremic syndrome.

, 2014
32 p.-4 tab-3 fig.-2 tab. suppl.Background and objectives Atypical hemolytic uremic syndrome is characterized by vascular endothelial damage caused by complement dysregulation.
Roldán, María Luisa Justa, Rodríguez de Córdoba, Santiago, Sheila Pinto, Sánchez-Corral, Pilar, Maria Luisa Justa Roldan, Marta Adragna, Adragna, Marta, López, Laura, Laura Lopez, Hoppe, Bernd, Antonia Peña, Peña, Antonia, López-Trascasa, Margarita, Sánchez Chinchilla, Daniel, Margarita Lopez Trascasa, Daniel Sánchez Chinchilla, Santiago Rodríguez de Córdoba, Bernd Hoppe, Pilar Sánchez-Corral, Pinto, Sheila   +19 more
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A Case of Severe Pre‐Eclampsia Complicated by HELLP Syndrome and Extensive Hepatic Infarction

Clinical Case Reports
Extensive hepatic infarction is a rare but potentially fatal complication of HELLP syndrome and is often difficult to recognize because of nonspecific clinical manifestations.
Tiange Xia, Fei Gao, Fengming Liang, Yang Shao   +3 more
doaj   +1 more source

Analysis of causes and outcomes of principal secondary thrombotic microangiopathy: a 9-year cohort study from a tertiary pediatric center in China

Research and Practice in Thrombosis and Haemostasis
Background: Few large-scale cohort studies have reviewed consecutive cases of thrombotic microangiopathy (TMA), especially in children. Objectives: The aim of our study was to evaluate causes and outcomes of TMA at a tertiary pediatric center in China ...
Dan Wu, Jie Zheng, Jun Yang, Bin Wang, Guanghua Zhu, Zhi Chen, Qiang Sun, Nan Zhou, Zhenping Chen, Yanhui Luo, Wei Yang, Xiaoyu Tian, Hejia Zhang, Xue Liu, Lei Lei, Na Tian, Kaige Zhang, Li Fang, Lan Mi, Ang Wei, Ying Liang, Maoquan Qin, Xiaorong Liu, Chenguang Jia   +23 more
doaj   +1 more source

Atypical hemolytic uremic syndrome in a child: A rare case report

Clinical Case Reports
Key Clinical Message Atypical hemolytic uremic syndrome, a rare thrombotic microangiopathy, necessitates early diagnosis and comprehensive care due to its potential severity, emphasizing the importance of a multidisciplinary approach to improve outcomes.
Bishal Kunwor, Bishal Sharma, Suchit Thapa Chhetri, Prerana Joshi, Dipendra Pradhan   +4 more
doaj   +1 more source

ATYPICAL HEMOLYTIC UREMIC SYNDROME DIAGNOSIS AND TREATMENT

Hematology, Transfusion and Cell Therapy
Atypical hemolytic uremic syndrome (aHUS), more commonly known as complement-related HUS is a kind of thrombotic microangiopathy (TMA) characterized by inherited pathogenic variants in complement genes or acquired autoantibodies against complement ...
Atakan Turgutkaya
doaj   +1 more source

Skin involvement in atypical hemolytic uremic syndrome

, 2014
Skin involvement in atypical hemolytic uremic syndrome (aHUS) is very uncommon and therefore often unrecognized as a specific symptom of aHUS. We describe 3 cases of patients with aHUS who developed skin lesions that completely recovered when disease ...
S. Testa, S. Salardi, ARDISSINO, GIAN LUIGI, F. Tel, A. V. Marzano, R. Lazzari, A. Edefonti   +6 more
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When two rare diseases meet: atypical hemolytic uremic syndrome and alkaptonuria in two siblings. [PDF]

CEN Case Rep
Karaca C, Karatas B, Tunc R, Erdem M, Dincer MT, Mirioglu S.   +5 more
europepmc   +1 more source