Results 81 to 90 of about 8,636 (197)

Catastrophic Antiphospholipid Syndrome in a Young Female Complicated by Systemic Lupus Erythematosus and Left Atrial Myxoma: A Rare Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Catastrophic antiphospholipid syndrome (CAPS) is a fulminant and rare variant of antiphospholipid syndrome characterized by rapidly progressive multiorgan thrombosis and a high mortality rate. Its diagnosis is often challenging due to overlapping clinical features with sepsis, thromboembolic disorders, and systemic autoimmune diseases.
Nazmin Ahmed, Mohammad Nazrul Hossain, Abdullah Salman, Sabrina Yesmin, S. M. G. Saklayen   +4 more
wiley   +1 more source

Multiple Myeloma as the Underlying Cause of Thrombotic Microangiopathy Leading to Acute Kidney Injury: Revisiting a Very Rare Entity

Journal of Investigative Medicine High Impact Case Reports, 2017
Thrombotic microangiopathy (TMA) describes a pathological process of microvascular thrombosis, consumptive thrombocytopenia, and microangiopathic hemolytic anemia, leading to end-organ ischemia and infarction, affecting particularly the kidney and brain.
Savneek Chugh MD, Asim Kichloo MD, Firas Jafri MD, Liga Yusvirazi MD, Robert Lerner MD   +4 more
doaj   +1 more source

The Complement System in Post‐Transplant Kidney Injury

Organ Medicine, EarlyView.
Mengsi Hu
wiley   +1 more source

Shifting From Systemic to Precision‐Targeted Complement Therapies: Opportunities and Hurdles

European Journal of Immunology, Volume 56, Issue 6, June 2026.
Complement therapeutics have expanded considerably, but systemic inhibitors remain limited by infection risks, breakthrough events, and loss of physiological functions. Emerging targeted approaches aim for organ‐, tissue‐, or cell‐specific modulation of complement activity, potentially offering greater precision while reducing treatment burden and ...
Marco Mannes, Wioleta M. Zelek, Leendert A. Trouw   +2 more
wiley   +1 more source

Exercise‐induced vasculitis with histological and genetic evidence of complement involvement

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Massimo Cugno, Paolo Calzari, Alessandra Di Benedetto, Francesca Laura Boggio, Chiara Moltrasio, Luigi Porcaro, Angelo Valerio Marzano   +6 more
wiley   +1 more source

Pathophysiology and treatment of typical and atypical hemolytic uremic syndrome [PDF]

, 2015
International audienceHemolytic uremic syndrome is a rare disease, frequently responsible for renal insufficiency in children. Recent findings have led to renewed interest in this pathology. The discovery of new gene mutations in the atypical form of HUS
Montana, Marc, P. Vanelle, Vanelle, P., Vanelle, Patrice, Bornet, C., picard, camille, Montana, M., C. Curti, Curti, C., C. Bornet, Curti, Christophe, Picard, C., M. Montana, bornet, charleric, Burtey, S., S. Burtey, C. Picard, Burtey, Stéphane   +17 more
core   +1 more source

Ribosomal Proteins in Cell Biology and Cancer

MedComm – Oncology, Volume 5, Issue 2, June 2026.
The functions of ribosomal proteins (RPs) extend beyond the conventional translation process, as they also regulate gene expression, stress responses, and disease progression. Dysregulation of RPs contributes to the onset and progression of various diseases, including cancer and ribosomopathies, underscoring their dual role as critical disease ...
Ao Zhang, Zeguang Sun, Xinyang Song, Xikun Zhou, Jing Li   +4 more
wiley   +1 more source

Atypical hemolytic uremic syndrome in tertiary hospital, Pakistan [PDF]

, 2016
Atypical hemolytic uremic syndrome (HUS) is a rare disorder in children, therefore it may lead to misdiagnosis, delay in treatment, or acute kidney injury.
Badruddin, Shirin, Rattani, Salma
core  

Hemolytic uremic syndrome and IgA nephropathy in a child: Coincidence or not?

The Turkish Journal of Pediatrics, 2018
A previously healthy 18-month old boy, presenting with diarrhea, anemia, thrombocytopenia and acute renal failure was admitted to our hospital. Hemolytic uremic syndrome (HUS) was diagnosed with his clinical and laboratory findings.
Serra Sürmeli-Döven, Ali Delibaş, İclal Gürses, Uğur Raşit Kayacan, Banu Coşkun-Yılmaz, Kaan Esen, Emine Korkmaz, Fatih Özaltın   +7 more
doaj   +1 more source

Impact of hypertensive emergency and complement rare variants on presentation and outcome of atypical hemolytic uremic syndrome: Hypertensive emergency and hemolytic uremic syndrome [PDF]

, 2019
International audienceAtypical hemolytic uremic syndrome is a prototypic thrombotic microangiopathy attributable to complement dysregulation. Hypertensive emergency, characterized by elevation of systolic (>180mmHg) or diastolic (>120mmHg) blood pressure
Vieira-Martins, Paula, Mesnard, Laurent, Florence Aulagnon, Laurent Mesnard, Petitprez, F., Florent Petitprez, Matignon, Marie, Fakhouri, F., Halimi, J. M., El Karoui, K., Idris Boudhabhay, Karoui, Khalil,, Fakhouri, Fadi, Petitprez, Florent, Marie Matignon, Khalil El Karoui, Paula Vieira-Martins, Halimi, Jean-Michel, Karoui, Khalil, El, Zuber, J., Boudhabhay, Idris, Matignon, M., Frémeaux-Bacchi, Véronique, Boudhabhay, I., Vieira-Martins, P., Mesnard, L., Fadi Fakhouri, Véronique Frémeaux-Bacchi, Julien Zuber, Rondeau, E., Rondeau, Eric, Eric Rondeau, Aulagnon, F., Jean-Michel Halimi, Fremeaux-Bacchi, V., Aulagnon, Florence, Zuber, Julien   +36 more
core   +2 more sources