Results 51 to 60 of about 360,888 (187)

Tuberous sclerosis mimicking optic neuritis due to raised intracranial pressure: A diagnostic masquerade

Indian Journal of Ophthalmology. Case Reports
Tuberous sclerosis complex (TSC) is a rare phakomatosis with multisystem involvement. We report a 12-year-old girl with progressive bilateral vision loss, papilledema, and facial angiofibromas, initially suggestive of atypical optic neuritis.
Dhwanee Agarwal, Sukriti Gupta, Shreya Chandra, Harinder S Sethi   +3 more
doaj   +1 more source

p‐Brain: A Modular Open‐Source Framework for Automated Quantitative DCE‐MRI of Cerebral Perfusion, Microvasculature, and Blood–Brain Barrier Permeability

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT We present p‐Brain, a modular, open‐source framework for reproducible, automated quantitative DCE‐MRI at scale. Rather than a fixed pipeline, p‐Brain is built from interchangeable stages (ingestion, T1/M0$$ {T}_1/{M}_0 $$ fitting, vascular and tissue ROI extraction, signal‐to‐concentration conversion, kinetic modeling, and quality control ...
Edis D. Tireli, Stig P. Cramer, Ulrich Lindberg, Derya Tireli, Mark B. Vestergaard, Henrik B. W. Larsson   +5 more
wiley   +1 more source

Atypical Presentation of Optic Neuritis in a Patient with Active Hepatitis C Infection: A Case Report

Sclerosis
Background/Objectives: Optic neuritis is associated with demyelinating diseases such as multiple sclerosis (MS), but atypical presentations, particularly bilateral optic nerve involvement or coexisting systemic symptoms, necessitate broader diagnostic ...
Oreoluwa E. Morakinyo, Divya Sharma, Vijaya Valaparla, Laura J. Wu, Chilvana Patel   +4 more
doaj   +1 more source

Inborn errors of immunity in children with neuroinflammation

Developmental Medicine &Child Neurology, EarlyView.
Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu, Dilan Dissanayake, Jessie Cunningham, Helen Branson, Ori Scott, E Ann Yeh   +5 more
wiley   +1 more source

Critically Ill Children Show Disrupted Sleep Patterns and Atypical Electroencephalograms: An Observational Cohort Study

Acta Paediatrica, Volume 115, Issue 10, Page 2323-2331, October 2026.
ABSTRACT Aim Sleep disruptions are common in hospitalised children. This study described sleep in critically ill and non‐critically ill hospitalised children, including young infants and patients with central nervous system injuries. Methods This observational cohort study included two groups: critically ill children admitted to a paediatric intensive ...
Eris van Twist, Arnout B. G. Cramer, Sascha C. A. T. Verbruggen, Maartje Louter, Karlien Veldscholte, Koen F. M. Joosten, Matthijs de Hoog, Karla Biesheuvel, Dirk C. G. Straver, Rogier C. J. de Jonge   +9 more
wiley   +1 more source

A sphenoid sinus mucocele simulating as retro bulbar optic neuritis

Indian Journal of Ophthalmology, 2012
A 25-year-old male presented with complaints of sudden diminution of vision with pain on eye movement in the left eye which was diagnosed clinically as retro bulbar optic neuritis.
Anoop Kishore Gupta, Vimla Menon, Pradeep Sharma, Rohit Saxena, Senthil Kumaran   +4 more
doaj   +1 more source

Sudden visual loss after COVID-19 infection with diabetic ketoacidosis

Indian Journal of Ophthalmology. Case Reports
We report a case of an atypical optic neuritis (AION) in an adolescent male, diagnosed with diabetic ketoacidosis in the setting of a coronavirus disease 2019 (COVID-19) infection.
Laxmi Tuli, Subina Narang, Mahima Kansal, Nitesh Dhayal   +3 more
doaj   +1 more source

Acute visual loss after ipilimumab treatment for metastatic melanoma

Journal for ImmunoTherapy of Cancer, 2016
Background Ipilimumab, a humanized CLTA-4 antibody is a standard therapy in the treatment of advanced melanoma. While ipilimumab provides an overall survival benefit to patients, it can be associated with immune related adverse events (IrAEs).Case ...
Melissa A. Wilson, Kelly Guld, Steven Galetta, Ryan D. Walsh, Julia Kharlip, Madhura Tamhankar, Suzanne McGettigan, Lynn M. Schuchter, Leslie A. Fecher   +8 more
doaj   +1 more source

When to consider an inborn error of immunity: clues for physicians

Internal Medicine Journal, Volume 56, Issue 9, Page 1488-1499, September 2026.
Abstract The term inborn errors of immunity (IEIs) refers to the rapidly expanding group of genetic disorders causing dysregulation of the immune system. With improved genetic testing in recent years, the number of defined IEIs and their range of phenotypic presentations has grown vastly, with more than 550 IEIs now described.
Meera Thangarajah, Lucinda J. Berglund
wiley   +1 more source

Optic neuritis: relation between inflammatory genetic markers and occurrence of the disease

Neurologijos seminarai, 2019
Optic neuritis (ON) is characterized as an inflammation of the optic nerve. Based on etiology, ON is classified to typical and atypical forms. Typical ON is often related to multiple sclerosis while atypical ON can be caused by various infections ...
V. Punytė , R. Liutkevičienė
doaj   +1 more source