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Current Knowledge on Atypical Parathyroid Tumors and Emerging Strategies for Risk Stratification [PDF]

open access: yesEndocrinology and Metabolism
Atypical parathyroid tumors (APTs) are an uncommon subset of parathyroid neoplasms that carry substantial clinical relevance because of their histological and clinical resemblance to parathyroid cancer.
Hye-Sun Park   +4 more
doaj   +4 more sources

Parathyroid carcinoma and atypical parathyroid tumor: analysis of an Italian database

open access: yesEuropean Journal of Endocrinology
Abstract Objective Atypical parathyroid tumor (aPT) and parathyroid carcinoma (PC) are extremely rare parathyroid neoplasms, accounting together for <2% of all parathyroid tumors. They often present an overlapping clinical phenotype, sharing clinical, biochemical, and some histological features.
Francesca Marini   +25 more
openaire   +5 more sources

The Role of Parafibromin, Galectin-3, HBME-1, and Ki-67 in the Differential Diagnosis of Parathyroid Tumors

open access: yesOman Medical Journal, 2015
Objectives: Parathyroid carcinoma (PC) is a rare parathyroid tumor compared to parathyroid adenoma (PA) and atypical parathyroid adenoma (APA). Recent studies have suggested parafibromin has a role in the differential diagnosis of parathyroid tumors.
Serap Karaarslan   +6 more
doaj   +3 more sources

Lymphatic and blood vessels in parathyroid tumors: Immunohistochemical study with LYVE-1 and von Willebrand factor [PDF]

open access: yesBiomolecules & Biomedicine
Parathyroid tumors exhibit distinct histopathological features that differentiate benign from malignant lesions. This study aimed to study characteristic distribution of lymphatic and blood vessels in normal parathyroid gland and parathyroid tumors to ...
Tatsuo Tomita
doaj   +2 more sources

Efficacy of surufatinib in the treatment of advanced parathyroid carcinoma: A case report

open access: yesHeliyon
Parathyroid cancer is an extremely rare form of neuroendocrine malignancy. Apart from surgery, the effectiveness of chemotherapy and radiotherapy is limited, and the efficacy of targeted drugs remains unclear.
Zhiyong Yu   +9 more
doaj   +2 more sources

Atypical parathyroid tumor: clinical and parathyroid hormone response to surgical treatment. [PDF]

open access: yesAnn Surg Treat Res, 2023
Primary hyperparathyroidism (PHPT) is caused by typical adenoma (TA), multiglandular disease (MD), or parathyroid carcinoma (PC), and in a smaller percentage of cases by atypical parathyroid tumor (APT). The objective of this study is the retrospective analysis of clinical features and parathyroid hormone (PTH)/calcium response to surgery in patients ...
Napolitano AG   +6 more
europepmc   +3 more sources

Transcriptome sequencing reveals distinct atypical parathyroid tumor subtypes. [PDF]

open access: yesEndocr Relat Cancer
Abstract Atypical parathyroid tumors (APTs) are a rare subtype of parathyroid neoplasms characterized by diagnostic challenges and an uncertain prognosis. This study aimed to validate the subtypes of APTs using transcriptome sequencing.
Park HS   +7 more
europepmc   +3 more sources

A retrospective study on a nomogram combining clinical and ultrasound parameters for differentiating solitary parathyroid adenoma from carcinoma or atypical tumors

open access: yesFrontiers in Endocrinology
ObjectiveParathyroid carcinoma (PC) and atypical parathyroid tumor (APT) are rare malignant parathyroid disorders with varying degrees of recurrence risk.
Chunrui Liu   +8 more
doaj   +3 more sources

Atypical Parathyroid Tumor and Hyperparathyroidism, and Their Association With the CDC73 Mutation in a Pediatric Patient. [PDF]

open access: yesCureus
Primary hyperparathyroidism (PHPT) is rare in the pediatric population and often presents with pronounced symptoms due to delayed recognition. Atypical parathyroid tumors, or neoplasms of uncertain malignant potential, are even less common in children and may indicate an underlying genetic disorder.
Gullapalli VD, Chen J.
europepmc   +3 more sources

Atypical Parathyroid Tumor: A Case Report on the Diagnostic and Therapeutic Approach. [PDF]

open access: yesCureus
Theofilopoulou S   +4 more
europepmc   +2 more sources

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