Results 41 to 50 of about 1,506,220 (180)

SAT179 Germline And Somatic Inactivating FLCN Variants In Parathyroid Cancer and Atypical Parathyroid Tumors

Journal of the Endocrine Society, 2023
Abstract Disclosure: S. Jha: None. J. Welch: None. R. Tora: None. J. Lack: None. A. Warner: None. J. Del Rivero: None. S.M. Sadowski: None. N. Nilubol: None. L. Schmidt: None. W.M. Linehan: None. L.S. Weinstein: None. W.F. Simonds: None. S.K. Agarwal: None.
Jha, Smita, Welch, James, Tora, Rana, Lack, Justin, Warner, Andrew, Del Rivero, Jaydira, Mercedes Sadowski, Samira, Nilubol, Naris, Schmidt, Laura, Linehan, W M, Scott Weinstein, Lee, Simonds, William F, Kishore Agarwal, Sunita   +12 more
openaire   +1 more source

Atypical parathyroid adenoma with clinically aggressive course of hyperparathyroidism: clinical case report

Эндокринная хирургия, 2018
Primary hyperparathyroidism is common clinical endocrine disorder with a prevalence between 12%. Solitary parathyroid adenomas account from 80 to 85% of cases of PHPT, hyperplasia and multiple adenomas is up to 15%, parathyroid carcinoma is a very rare ...
Natalia G. Mokrysheva, Anna K. Eremkina, Konstantin U. Slashchuk, Alexey I. Bespalov, Iya А. Voronkova, Pavel O. Rumyantsev, Mikhail V. Degtyarev, Nikolay S. Kuznetzov, Nonna V. Latkina   +8 more
doaj   +1 more source

Parathyroid Carcinoma: Ultrasonographic and Clinical Experience

Acta Clinica Croatica, 2023
Parathyroid cancer is an extremely rare malignancy that usually leads to hyperparathyroidism. The aim of this report is to present clinical and ultrasonographic features of tumors in six patients (5 females; mean age 53.2 years) treated for parathyroid
Marina Jadrešić, Sanja Kusačić Kuna, Hrvojka Tomić Brzac, Maja Baretić, Dražen Huić   +4 more
doaj   +1 more source

ATYPICAL PARATHYROID TUMOR

Journal of the ASEAN Federation of Endocrine Societies
INTRODUCTION/BACKGROUNDDifferentiating between benign and malignant parathyroid nodules is a clinical and pathological challenge. Unlike other tumours, parathyroid carcinoma lacks definitive preoperative biomarkers. The diagnosis is frequently made retrospectively based on surgical pathology.
Syahidatul Wafa, Em Yunir
openaire   +1 more source

FLCN Variants in Parathyroid Carcinoma and Atypical Parathyroid Tumors

Journal of the Endocrine Society
Abstract Parathyroid carcinoma (PC) and atypical parathyroid tumors (APT) are incompletely understood and pose challenges in definitive diagnosis. FLCN sequence variants have recently been linked to PC and APT. Inactivating mutations in the ubiquitously expressed FLCN tumor suppressor gene, encoding folliculin, cause Birt-Hogg-Dubé ...
Callie Shea Burke, Justin Bellizzi, Jessica Costa-Guda, Andrew Arnold   +3 more
openaire   +2 more sources

A case of intrathyroid parathyroid tumor that was difficult to diagnose by ultrasonography

The Ultrasound Journal, 2020
Background With advances in diagnostic imaging such as ultrasonography (US), computed tomography (CT), and 99mTc-MIBI-sestamibi (MIBI) scintigraphy, localized diagnosis of hyperparathyroidism (pHPT) has become possible with considerable accuracy. However,
Nobuyuki Takemoto, Ai Koyanagi, Masanori Yasuda, Yuya Yamamoto, Hiroshi Yamamoto   +4 more
doaj   +1 more source

The roles of the tumor suppressor parafibromin in cancer

Frontiers in Cell and Developmental Biology, 2022
In this review, we discuss parafibromin protein, which is encoded by CDC73. A mutation in this gene causes hyperparathyroidism-jaw tumor (HPT-JT) syndrome, an autosomal dominant disease.
Hua-chuan Zheng, Hang Xue, Cong-yu Zhang
doaj   +1 more source

Surgery After Thermal Ablation of Thyroid Nodules: A Systematic Review of Surgical Risk, Strategy and Pathological Findings

Head &Neck, EarlyView.
ABSTRACT Background Thermal ablation is increasingly used for selected thyroid nodules, but some patients subsequently require thyroidectomy. The effect of prior ablation on surgical risk, operative strategy, and histopathology remains unclear. Methods PubMed/MEDLINE, EMBASE, and the Cochrane Library were searched from inception to May 2026 for studies
Francesco Brucchi, Federica Poli, Beatrice Sperotto, Carla Colombo, Laura Fugazzola, Gianlorenzo Dionigi   +5 more
wiley   +1 more source

A Case of Paratesticular Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma [PDF]

, 2015
A very rare case of paratesticular atypical lipomatous tumor/a case of welldifferentiated liposarcoma diagnosed in an elderly patient is presented together with macroscopic surgical photographs and photographs of microscopic pathological ...
Yorukoglu, Kutsal, Hikmet Köseoğlu, Kutsal Yörükoğlu, Koseoglu, Hikmet   +3 more
core   +1 more source

Severe Hypercalcemia as Presentation of Atypical Cystic Parathyroid Adenoma: A Case Report

Annals of Internal Medicine: Clinical Cases
Because of their similarities with parathyroid carcinomas, atypical parathyroid adenomas constitute a challenge for pathologists. The diagnosis of this kind of parathyroid tumor also can be difficult for clinicians because of the low accuracy of imaging ...
Paola G. Donoso Naranjo, Macarena Naranjo Arellano, Esteban Castillo Sánchez-Heredero, Isabel Martín Garrido   +3 more
doaj   +1 more source