Atypical Porcine Pestivirus as a Novel Type of Pestivirus in Pigs in China. [PDF]
Front Microbiol, 2017 Pestiviruses are highly variable RNA viruses. A growing number of novel pestiviruses has been discovered in domestic and wild species in the last two decades.
Yuan J +11 more
europepmc +15 more sources
Distribution and persistence of atypical porcine pestivirus in experimentally inoculated pigs. [PDF]
J Vet Diagn Invest, 2021 Atypical porcine pestivirus (APPV) is a cause of congenital tremors (CTs) in piglets and has been found in swine populations around the globe. Although systemic distribution of the virus has been reported, there is limited information regarding viral ...
Buckley AC +8 more
europepmc +6 more sources
Phylogenetic and codon usage analysis of atypical porcine pestivirus (APPV). [PDF]
Virulence, 2020 Atypical porcine pestivirus (APPV) has been identified as the main causative agent for congenital tremor (CT) type A-II in piglets, which is threatening the health of the global swine herd. However, the evolution of APPV remains largely unknown.
Pan S, Mou C, Wu H, Chen Z.
europepmc +8 more sources
DNAJC14-Independent Replication of the Atypical Porcine Pestivirus. [PDF]
J Virol, 2022 DNAJC14 is an essential cofactor of the pestiviral NS2 autoprotease, limiting replication to tolerable levels as a prerequisite for the noncytopathogenic biotype of pestiviruses.
Reuscher CM +13 more
europepmc +4 more sources
Development of a Crystal Digital RT-PCR for the Detection of Atypical Porcine Pestivirus. [PDF]
Vet Sci, 2023 Simple Summary Atypical porcine pestivirus (APPV), a newly discovered virus, is associated with the type A-II congenital tremor (CT) in neonatal piglets.
Liu H +5 more
europepmc +5 more sources
Detection and investigation of atypical porcine pestivirus in a swine production system. [PDF]
Front Vet Sci, 2022 A commercial farrow-to-finish farm was suspicious of atypical porcine pestivirus (APPV) after observing clinical signs of congenital tremors (CT) and splay leg (SL) of newborn pigs.
Houston GE +6 more
europepmc +5 more sources
Genetic diversity and detection of atypical porcine pestivirus infections. [PDF]
J Anim Sci, 2022 Atypical porcine pestivirus (APPV), an RNA virus member of the Flaviviridae family, has been associated with congenital tremor in newborn piglets. Previously reported qPCR-based assays were unable to detect APPV in novel cases of congenital tremor ...
Sutton KM +6 more
europepmc +4 more sources
The Diversity and Spatiotemporally Evolutionary Dynamic of Atypical Porcine Pestivirus in China. [PDF]
Front Microbiol, 2022 The presence of congenital tremor (CT) type A-II in newborn piglets, caused by atypical porcine pestivirus (APPV), has been a focus since 2016. However, the source, evolutionary history, and transmission pattern of APPV in China remain poorly understood.
Ma H +6 more
europepmc +5 more sources
Disruption of interferon-β production by the Npro of atypical porcine pestivirus. [PDF]
Virulence, 2021 Atypical porcine pestivirus (APPV) is an emerging porcine virus that threatens global swine production. Pestiviruses can prevent interferon (IFN) production to avoid the host innate immune response, and the Npro viral protein can play a critical role ...
Mou C, Pan S, Wu H, Chen Z.
europepmc +7 more sources
Detection of atypical porcine pestivirus in Swedish piglets with congenital tremor type A-II. [PDF]
BMC Vet Res, 2020 Background Congenital tremor (CT) type A-II is a neurological disorder characterized by tremor of the head and body of newborn piglets. The suggested causative agent of the disease is the recently found atypical porcine pestivirus (APPV).
Stenberg H, Jacobson M, Malmberg M.
europepmc +6 more sources