Results 131 to 140 of about 122,908 (260)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Identification of Au-hydrides as key intermediates in the reduction of Au(iii) prodrugs to active Au(i) species under protic conditions. [PDF]

Chem Sci
Ochs J, Metzler-Nolte N.
europepmc   +1 more source

Synthesis and Selective Au(III) Adsorption of Ureido Polymers Containing Large Repeating Rings. [PDF]

ACS Omega, 2021
Sun Y, Ding Y, Zhou W, Wang X, Tan C, Matsumura Y, Ochiai B, Chu Q.   +7 more
europepmc   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Harnessing Organometallic Au(III) Complexes as Precision Scaffolds for Next-Generation Therapeutic and Imaging Agents. [PDF]

Chembiochem
Thomas SR, Bonsignore R.
europepmc   +1 more source

Unprecedented Mechanochemical Synthesis and Heterogenization of a C-Scorpionate Au(III) Catalyst for Microwave-Assisted Biomass Valorization. [PDF]

Nanomaterials (Basel), 2022
Matias IAS, Selfa PG, Ferraria AM, Botelho do Rego AM, Kopylovich MN, Ribeiro APC, Martins LMDRS.   +6 more
europepmc   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

C-C Cross-Couplings from a Cyclometalated Au(III) C ∧ N Complex: Mechanistic Insights and Synthetic Developments. [PDF]

Chemistry, 2021
Bonsignore R, Thomas SR, Rigoulet M, Jandl C, Pöthig A, Bourissou D, Barone G, Casini A.   +7 more
europepmc   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Amino-Modified ZIF-90 for Effective Adsorption of Au(III) in Environmental Water. [PDF]

Molecules
Zhou N, Wu X, Wang S, Qu J, Tan Y, Luan C, Yin X, Wu X, Zhuang X.   +8 more
europepmc   +1 more source