Results 31 to 40 of about 748,707 (290)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Geriatric Fracture Centre (German Trauma Society): guidelines and certification to improve geriatric trauma care

Innovative Surgical Sciences, 2016
Because of demographic changes and the increasing proportion of orthogeriatric patients, the German Trauma Society (DGU) established a certification process for geriatric fracture centres (AltersTraumaZentrum DGU®).
Krause Ulla, Jung Katrin
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Stabilization of compressed earth blocks using recycled thermoplastics: experimental study of key parameters

Scientific Reports
The construction sector is a major contributor to global resource depletion and environmental pollution, particularly due to its reliance on energy-intensive and water-demanding materials such as cement and fired clay.
Laila H. Salem, Yassin Aly, Berlant Arab, May Haggag, Safwan Khedr   +4 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Sustainable nanomedicine: exploiting fruit and vegetable waste-derived extracts for targeted anticancer application

Cancer Nanotechnology
Background Despite significant advances in oncology, cancer therapy remains constrained by systemic toxicity, limited tumor selectivity, and the progressive emergence of drug resistance.
Nouran S. Sharaf, Amro Shetta, Razan Farrag, Noha El Salakawy, Wael Mamdouh   +4 more
doaj   +1 more source

Comparison of Machine Learning Models for Heart Disease Classification with Web-Based Implementation

Journal of Applied Informatics and Computing
Heart disease has become one of the most concerning diseases in Indonesia according to research published in 2018 by the Health Ministry of Indonesia. Based on said research, 15 out of 1000 Indonesians suffer from heart disease. Furthermore, according to
Angga Ramda Ramadhan, Nandang Saefulloh, Nisa Utami, Muji Diana, Abiyyu Aji Prasetyo Utomo, Yusuf Eka Wicaksana   +5 more
doaj   +1 more source

Adoption value of serum hematological inflammatory markers in early diagnosis of necrotising enterocolitis [PDF]

Journal of Medical Biochemistry
Background: Early diagnosis and intervention of neonatal necrotising enterocolitis (NEC) are crucial for improving prognosis. It was to assess the diagnostic and staging value of high-sensitivity C-reactive protein (hs-CRP), white blood cell count (WBC),
Luo Ruogu, Zhang Jing, Li Xiaolong, Peng Fei, Zhang Anpeng, Zhang Pengfei   +5 more
doaj   +1 more source