Results 51 to 60 of about 748,707 (290)

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

AUC-based Selective Classification

CoRR, 2022
Selective classification (or classification with a reject option) pairs a classifier with a selection function to determine whether or not a prediction should be accepted. This framework trades off coverage (probability of accepting a prediction) with predictive performance, typically measured by distributive loss functions.
Pugnana, Andrea, Ruggieri, Salvatore
openaire   +5 more sources

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Klasifikasi Judul Berita Online Menggunakan Multinomial Naïve Bayes

Al-Khwarizmi: Jurnal Pendidikan Matematika dan Ilmu Pengetahuan Alam
: News is defined as stories or information about current events. News can be classified into two categories, namely hard news and soft news. Generally, hard news refers to news topics that are timely, important and consequential.
Lilis Laome, Dian Christien Arisona, Zelianti, Gusti Ngurah Adhi Wibawa, Irma Yahya, Mukhsar   +5 more
doaj   +1 more source

AUC Optimization with a Reject Option

Proceedings of the AAAI Conference on Artificial Intelligence, 2020
Making an erroneous decision may cause serious results in diverse mission-critical tasks such as medical diagnosis and bioinformatics. Previous work focuses on classification with a reject option, i.e., abstain rather than classify an instance of low confidence.
Song-Qing Shen, Bin-Bin Yang, Wei Gao 0008   +2 more
openaire   +3 more sources

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Evaluation of Shannon entropy in order to flood probability and susceptibility mapping at Haraz catchment [PDF]

مخاطرات محیط طبیعی, 2016
One of the main measures in order to financial and life damages reduction is a production of flood susceptibility mapping. In the current research, Shannon entropy has been studied to determine the flood probability and susceptibility mapping.
Ebrahim Nohani, fariba darabi, edris maroofinia, khebat khosravi   +3 more
doaj   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Quantification of thermal dose in moderate clinical hyperthermia with radiotherapy: a relook using temperature–time area under the curve (AUC)

International Journal of Hyperthermia, 2021
Background Thermal dose in clinical hyperthermia reported as cumulative equivalent minutes (CEM) at 43 °C (CEM43) and its variants are based on direct thermal cytotoxicity assuming Arrhenius ‘break’ at 43 °C.
Niloy R. Datta, Dietmar Marder, Sneha Datta, Andreas Meister, Emsad Puric, Emanuel Stutz, Susanne Rogers, Brigitte Eberle, Olaf Timm, Michal Staruch, Oliver Riesterer, Stephan Bodis   +11 more
doaj   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source