Results 41 to 50 of about 536,893 (261)

Maximize AUC for Positive-Unlabeled Classification and Incremental Algorithm

Jisuanji kexue yu tansuo, 2020
Positive-unlabeled classification is referred to as PU classification. Since there are only positive samples and unlabeled samples, the traditional classification methods are not effective in PU classification.
MA Yumin, WANG Shitong
doaj   +1 more source

Partial AUC Estimation and Regression

Biometrics, 2003
Summary. Accurate diagnosis of disease is a critical part of health care. New diagnostic and screening tests must be evaluated based on their abilities to discriminate diseased from nondiseased states. The partial area under the receiver operating characteristic (ROC) curve is a measure of diagnostic test accuracy.
Dodd, Lori E., Pepe, Margaret S.
openaire   +4 more sources

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Does It Pay to Optimize AUC?

Proceedings of the AAAI Conference on Artificial Intelligence, 2023
The Area Under the ROC Curve (AUC) is an important model metric for evaluating binary classifiers, and many algorithms have been proposed to optimize AUC approximately. It raises the question of whether the generally insignificant gains observed by previous studies are due to inherent limitations of the metric or the inadequate quality of optimization.
Baojian Zhou, Steven Skiena
openaire   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Evaluation of Shannon entropy in order to flood probability and susceptibility mapping at Haraz catchment [PDF]

مخاطرات محیط طبیعی, 2016
One of the main measures in order to financial and life damages reduction is a production of flood susceptibility mapping. In the current research, Shannon entropy has been studied to determine the flood probability and susceptibility mapping.
Ebrahim Nohani, fariba darabi, edris maroofinia, khebat khosravi   +3 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Klasifikasi Judul Berita Online Menggunakan Multinomial Naïve Bayes

Al-Khwarizmi: Jurnal Pendidikan Matematika dan Ilmu Pengetahuan Alam
: News is defined as stories or information about current events. News can be classified into two categories, namely hard news and soft news. Generally, hard news refers to news topics that are timely, important and consequential.
Lilis Laome, Dian Christien Arisona, Zelianti, Gusti Ngurah Adhi Wibawa, Irma Yahya, Mukhsar   +5 more
doaj   +1 more source

Quantification of thermal dose in moderate clinical hyperthermia with radiotherapy: a relook using temperature–time area under the curve (AUC)

International Journal of Hyperthermia, 2021
Background Thermal dose in clinical hyperthermia reported as cumulative equivalent minutes (CEM) at 43 °C (CEM43) and its variants are based on direct thermal cytotoxicity assuming Arrhenius ‘break’ at 43 °C.
Niloy R. Datta, Dietmar Marder, Sneha Datta, Andreas Meister, Emsad Puric, Emanuel Stutz, Susanne Rogers, Brigitte Eberle, Olaf Timm, Michal Staruch, Oliver Riesterer, Stephan Bodis   +11 more
doaj   +1 more source