Results 61 to 70 of about 923,643 (274)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

An approach towards achieving net-zero-carbon concrete

open access: yesAdvances in Civil and Architectural Engineering
Carbon dioxide is the primary greenhouse gas contributing to climate change. The construction industry is a main contributor to carbon dioxide emissions worldwide and must make conscious efforts towards becoming a green industry by using materials that ...
Abdelrahman El Bialy   +8 more
doaj   +1 more source

Predicting Cardiovascular Risk Factors from Retinal Fundus Photographs using Deep Learning

open access: yes, 2017
Traditionally, medical discoveries are made by observing associations and then designing experiments to test these hypotheses. However, observing and quantifying associations in images can be difficult because of the wide variety of features, patterns ...
Blumer, Katy   +7 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

SENTIMENT ANALYSIS OF REVIEWS ON X APPS ON GOOGLE PLAY STORE USING SUPPORT VECTOR MACHINE AND N-GRAM FEATURE SELECTION

open access: yesBarekeng
Sentiment analysis is an application of text mining that is used to find out opinions from a set of textual data about a particular event or topic. The main function of sentiment analysis is to extract information and find the meaning and opinions of a ...
Fahri Aimar Kusumo   +2 more
doaj   +1 more source

Calculation of the total number of radiation decay of Radiolabelled-Octreotate using non-linear mixed effect models [PDF]

open access: yesITM Web of Conferences
Non-Linear Mixed Effect (NLME) is a method used in the area under the measured time-activity curve (AUC) calculations. The calculation of an accurate AUC is needed for an accurate determination of the radiation absorbed dose.
Pratiwi Nining   +2 more
doaj   +1 more source

Weakly Supervised AUC Optimization: A Unified Partial AUC Approach

open access: yesIEEE Transactions on Pattern Analysis and Machine Intelligence
Since acquiring perfect supervision is usually difficult, real-world machine learning tasks often confront inaccurate, incomplete, or inexact supervision, collectively referred to as weak supervision. In this work, we present WSAUC, a unified framework for weakly supervised AUC optimization problems, which covers noisy label learning, positive ...
Zheng Xie   +4 more
openaire   +3 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

CircCDYL Serves as a New Biomarker in Mantle Cell Lymphoma and Promotes Cell Proliferation

open access: yesCancer Management and Research, 2019
Mei Mei,1,2 Yingjun Wang,1 Qilong Wang,1 Yueyao Liu,3 Wenting Song,1 Mingzhi Zhang1 1Department of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People’s Republic of China; 2The Academy of Medical Sciences, Zhengzhou ...
Mei M   +5 more
doaj  

Resilient Modulus Characterization of Alaskan Granular Base Materials [PDF]

open access: yes, 2010
INE/AUC 11 ...
Li, Lin, Liu, Juanyu, Zhang, Xiong
core  

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