Results 91 to 100 of about 64,092 (306)

Speech and non-speech processing in children with phonological disorders: an electrophysiological study

Clinics, 2011
OBJECTIVE: To determine whether neurophysiological auditory brainstem responses to clicks and repeated speech stimuli differ between typically developing children and children with phonological disorders. INTRODUCTION: Phonological disorders are language
Isabela Crivellaro Gonçalves, Haydée Fiszbein Wertzner, Alessandra Giannella Samelli, Carla Gentile Matas   +3 more
doaj   +1 more source

Auditory brainstem responses as a biomarker for cognition

Communications Biology
AbstractA non-invasive, accessible and effective biomarker is critical to the diagnosis, monitoring and treatment of age-related cognitive decline. Recent work has suggested a strong association between auditory brainstem responses (ABR) and cognitive function in aging macaques. Here we show in 118 human participants (66 females; age range=18-92 years;
Yasmeen Hamza, Ye Yang, Janie Vu, Antoinette Abdelmalek, Mobina Malekifar, Carol A. Barnes, Fan-Gang Zeng   +6 more
openaire   +5 more sources

Contralateral inhibition of click- and chirp-evoked human compound action potentials [PDF]

, 2017
Cochlear outer hair cells (OHC) receive direct efferent feedback from the caudal auditory brainstem via the medial olivocochlear (MOC) bundle. This circuit provides the neural substrate for the MOC reflex, which inhibits cochlear amplifier gain and is ...
Cone, Barbara K, Lichtenhan, Jeffery T, Smith, Spencer B   +2 more
core   +2 more sources

Cortical contributions to the auditory frequency-following response revealed by MEG

Nature Communications, 2016
Auditory brainstem response (ABR) is used to study temporal encoding of auditory information in music and language. This study utilizes magnetoencephalography to localize both cortical and subcortical origins of the sustained frequency following response
Emily B. J. Coffey, Sibylle C. Herholz, Alexander M. P. Chepesiuk, Sylvain Baillet, Robert J. Zatorre   +4 more
doaj   +1 more source

Cognitive Changes in Pre‐ataxic Spinocerebellar Ataxias: A Scoping Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Although traditionally recognized for motor impairment, evidence suggests that cognitive deficits may emerge before ataxia onset in autosomal dominant spinocerebellar ataxias (SCA), particularly in nucleotide repeat expansion SCAs (NRE‐SCAs).
Renata Barreto Tenorio, Andressa Aline Vieira, Hélio Afonso Ghizoni Teive, Carlos Henrique Ferreira Camargo   +3 more
wiley   +1 more source

Discrimination of low-frequency tones employs temporal fine structure [PDF]

, 2012
An auditory neuron can preserve the temporal fine structure of a low-frequency tone by phase-locking its response to the stimulus. Apart from sound localization, however, little is known about the role of this temporal information for signal processing ...
A. J. Hudspeth, Evan Balaban, Tobias Reichenbach   +2 more
core   +3 more sources

Early‐Onset Movement Disorder Syndrome Caused by Biallelic Variants in PDE1B Encoding Phosphodiesterase 1B

Movement Disorders, EarlyView.
Abstract Background Breakdown of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) in basal ganglia cells through hydrolysis of diesteric bonds, primarily by PDE10A and PDE1B, is essential for normal human movement. While biallelic loss‐of‐function variants in PDE10A are known to cause hyperkinetic movement disorders, the ...
Tomer Poleg, Noam Hadar, Eyal Kristal, Nicola Y. Roberts, Vadim Dolgin, Ilana Aminov, Amit Safran, Nadav Agam, Matan Jean, Ofek Freund, Eamonn G. Sheridan, James A. Poulter, Michelle L. Thompson, Yusra Algoos, Salma Al‐Qahtani, Lama AlAbdi, Sateesh Maddirevula, Verity Hartill, Henry Houlden, Reza Maroofian, Amit Nahum, Ohad S. Birk   +21 more
wiley   +1 more source

Human Brainstem Exhibits higher Sensitivity and Specificity than Auditory-Related Cortex to Short-Term Phonetic Discrimination Learning

Scientific Reports, 2017
Phonetic discrimination learning is an active perceptual process that operates under the influence of cognitive control mechanisms by increasing the sensitivity of the auditory system to the trained stimulus attributes.
Stefan Elmer, Marcela Hausheer, Joëlle Albrecht, Jürg Kühnis   +3 more
doaj   +1 more source

Audiogenic reflex seizures in cats [PDF]

, 2015
This study aims at characterizing feline audiogenic reflex seizures (FARS). An online questionnaire was developed to capture information from owners with cats suffering FARS.
Bessant, C, Garosi, L, Harvey, RJ, Lowrie, M, Sparkes, A   +4 more
core   +2 more sources

Digital Therapeutics for Alzheimer's and Parkinson's Diseases: Current Trends and Future Perspectives

Medicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) and Parkinson's disease (PD), which are characterized by the accumulation of misfolded protein aggregates and cognitive/motor dysfunction, are the most prevalent neurodegenerative diseases (NDDs). Despite strategic investigations aimed at augmenting the pharmaceutical pipeline, available drugs for AD and PD merely slow
Yoo Joo Jeong, Hyun‐ju Lee, Jun‐Su Kim, Seung‐Jae Kim, Unhui Jo, Jin Yeop Park, Su Jin Jun, Won Seok Lee, Mingoo Song, Donggii Kim, Gyoujin Cho, Jeong‐Heon Song, Hyang‐Sook Hoe   +12 more
wiley   +1 more source