Results 91 to 100 of about 63,111 (319)
Background Auditory brainstem response (ABR) using click stimuli enables global objective estimation of hearing threshold. The application of chirp stimuli aims to produce synchronized response from large portion of hair cells in the basilar membrane ...
Amal El-Attar+3 more
doaj +1 more source
Isoquercitrin (IQ), a major bioactive compound in buckwheat (Fagopyrum esculentum Moench; BW), serves as a key mediator of the protective effects of BW against noise‐induced hearing loss (NIHL) by activating the Nrf2/HO‐1 signaling pathway, and oral administration of BW and IQ significantly attenuates oxidative stress and hair cell apoptosis through ...
Hojin Lee+6 more
wiley +1 more source
Adaptation of Binaural Processing in the Adult Brainstem Induced by Ambient Noise [PDF]
Interaural differences in stimulus intensity and timing are major cues for sound localization. In mammals, these cues are first processed in the lateral and medial superior olive by interaction of excitatory and inhibitory synaptic inputs from ipsi- and ...
Grothe, Benedikt+3 more
core +1 more source
What Does Iron Mean to an Oligodendrocyte?
ABSTRACT Iron is essential for life and plays a key role in multiple fundamental cellular functions. The brain has the highest rate of energy consumption, and within the brain, oligodendrocytes have the highest level of oxidative metabolism per volume. Oligodendrocytes also stain the strongest for iron.
Quinn W. Wade, James R. Connor
wiley +1 more source
Histological and functional aspects of Alpha-synuclein in neurodegeneration [PDF]
Alpha-synuclein has been implicated in the cellular mechanisms that control auditory sensitivity. In other systems it can also confer protection against cellular injury.
Lawler, Lauren Noelle
core +1 more source
Relating the variability of tone-burst otoacoustic emission and auditory brainstem response latencies to the underlying cochlear mechanics [PDF]
Forward and reverse cochlear latency and its relation to the frequency tuning of the auditory filters can be assessed using tone bursts (TBs). Otoacoustic emissions (TBOAEs) estimate the cochlear roundtrip time, while auditory brainstem responses (ABRs ...
Shera, Christopher A, Verhulst, Sarah
core +2 more sources
Phonetic discrimination learning is an active perceptual process that operates under the influence of cognitive control mechanisms by increasing the sensitivity of the auditory system to the trained stimulus attributes.
Stefan Elmer+3 more
doaj +1 more source
New insights into applications of base editor in hereditary disorders
Abstract Hereditary disorders are a group of diseases caused by genetic mutations or chromosomal variations. Although the incidence of each genetic disorder is relatively low, patients affected by the disease generally experience a range of severe symptoms, including blindness, disability, and even premature death. In addition, the available treatments
Maoping Cai+8 more
wiley +1 more source
Optogenetic stimulation of the cochlear nucleus using channelrhodopsin-2 evokes activity in the central auditory pathways [PDF]
Optogenetics has become an important research tool and is being considered as the basis for several neural prostheses. However, few studies have applied optogenetics to the auditory brainstem.
Boyden, Edward+11 more
core +1 more source
Evaluation of cochlear and auditory brainstem functions in COVID-19 patients; a case control study
Background Many viral infections can cause hearing loss due to affection of cochlear hair cells or neurogenic pathway. Although, the damage secondary to viral infections is mainly cochlear affection; auditory brainstem can be affected as well.
Adel Abdel-Maksoud Nassar+3 more
doaj +1 more source