Results 81 to 90 of about 938,483 (396)

Integration of auditory and visual communication information in the primate ventrolateral prefrontal cortex [PDF]

, 2006
The integration of auditory and visual stimuli is crucial for recognizing objects, communicating effectively, and navigating through our complex world.
Averbeck, BB, Diltz, MD, Romanski, LM, Sugihara, T   +3 more
core   +1 more source

Cryopreserved Human Otic Neuronal Spheroids Self‐assemble for Functional Connectivity Analysis and Long‐term Ototoxicity Evaluation

Advanced Science, EarlyView.
This study establishes a robust and reproducible protocol for generating human otic neuronal spheroids (hONS) from cryopreserved hPSC‐derived pre‐placodal ectoderm cells. These hONS further differentiate into functional SGN‐like neurons, which extend neurite projections toward both murine hair cells and human cortical organoids, thereby forming ...
Gaoying Sun, Yukai Wang, Man Wang, Xinyue Wang, Mingming Tang, Da Li, Jianhuan Qi, Xue Wang, Shujuan Sun, Lei Chen, Weibin An, Ligang Kong, Anqi Suo, Haibo Wang, Wenwen Liu, Lei Xu   +15 more
wiley   +1 more source

A physiologically inspired model for solving the cocktail party problem. [PDF]

, 2019
At a cocktail party, we can broadly monitor the entire acoustic scene to detect important cues (e.g., our names being called, or the fire alarm going off), or selectively listen to a target sound source (e.g., a conversation partner).
Chou, Kenny F., Colburn, H. Steven, Dong, Junzi, Sen, Kamal   +3 more
core   +1 more source

Nurr1 Orchestrates Claustrum Development and Functionality

Advanced Science, EarlyView.
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan, Andrew G. Newman, Pauline Lange, Susanne Müller, Marco Foddis, Stefan Paul Koch, Philipp Böhm‐Sturm, Maron Mantwill, Carsten Finke, Penghui Deng, Melissa Long, Dietmar Schmitz, Victor Tarabykin   +12 more
wiley   +1 more source

Functional connectivity and gray matter deficits within the auditory attention circuit in first-episode psychosis

Frontiers in Psychiatry, 2023
BackgroundSelective attention deficits in first episode of psychosis (FEP) can be indexed by impaired attentional modulation of auditory M100. It is unknown if the pathophysiology underlying this deficit is restricted to auditory cortex or involves a ...
Mark T. Curtis, Alfredo L. Sklar, Brian A. Coffman, Dean F. Salisbury   +3 more
doaj   +1 more source

The neural correlates of speech motor sequence learning [PDF]

, 2015
Speech is perhaps the most sophisticated example of a species-wide movement capability in the animal kingdom, requiring split-second sequencing of approximately 100 muscles in the respiratory, laryngeal, and oral movement systems. Despite the unique role
Beal, Deryk S., Guenther, Frank H., Segawa, Jennifer A., Tourville, Jason A.   +3 more
core   +1 more source

Theta‐gamma phase‐amplitude coupling in auditory cortex is modulated by language proficiency [PDF]

, 2023
Mikel Lizarazu, Manuel Carreiras, Nicola Molinaro   +2 more
openalex   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

The Corticofugal Effects of Auditory Cortex Microstimulation on Auditory Nerve and Superior Olivary Complex Responses Are Mediated via Alpha-9 Nicotinic Receptor Subunit.

PLoS ONE, 2016
Background and objectiveThe auditory efferent system is a complex network of descending pathways, which mainly originate in the primary auditory cortex and are directed to several auditory subcortical nuclei.
Cristian Aedo, Gonzalo Terreros, Alex León, Paul H Delano   +3 more
doaj   +1 more source

Neurons with stereotyped and rapid responses provide a reference frame for relative temporal coding in primate auditory cortex [PDF]

, 2012
The precise timing of spikes of cortical neurons relative to stimulus onset carries substantial sensory information. To access this information the sensory systems would need to maintain an internal temporal reference that reflects the precise stimulus ...
Brasselet, Romain, Kayser, Christoph, Logothetis, Nikos, Logothetis, Nikos K., Panzeri, Stefano   +4 more
core   +1 more source