Results 91 to 100 of about 322,258 (230)
Live Demonstration: Real-time neuro-inspired sound source localization and tracking architecture applied to a robotic platform [PDF]
, 2018 This live demonstration presents a sound source localization and tracking system implemented with Spike Signal Processing (SSP) building blocks on FPGA devices.
Cerezuela Escudero, Elena +3 more
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Electrical Control of the Transduction Channels’ Gating Force in Mechanosensory Hair Cells
Advanced Science, EarlyView.The inner ear's hair cells rely on mechanosensitive ion channels to convert vibrations of their hair‐bundle into electrical signals. We show that varying the electrical potential (U) across the sensory epithelium modulates a key determinant of mechanosensitivity—the gating force (FG)—by modulating the gating swing (d), ranging from the size of the ...
Achille Joliot +2 more
wiley +1 more source
Advanced Science, EarlyView.The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang +15 more
wiley +1 more source
Neural Response Reliability as a Marker of the Transition of Neural Codes along Auditory Pathways
Advanced ScienceThe neural representations of acoustic features that differ in the location or timbre of the emitter elicit similar perceptions, suggesting the existence of a robust stimulus‐response function between complex sounds and the activity of neural populations
Alexa Buck +7 more
doaj +1 more source
Air Pollution and the Auditory System at Risk: A Narrative Review
Auditory and Vestibular ResearchBackground and Aim: Air pollution has a negative impact on various body systems, including auditory system. The aim of this study was to provide a comprehensive review of research investigating the effects of air pollution on various levels of the ...
Nasrin Gohari +3 more
doaj +1 more source
Impact of Aging on the Auditory System and Related Cognitive Functions: A Narrative Review
Frontiers in Neuroscience, 2018 Age-related hearing loss (ARHL), presbycusis, is a chronic health condition that affects approximately one-third of the world's population. The peripheral and central hearing alterations associated with age-related hearing loss have a profound impact on ...
Dona M. P. Jayakody +8 more
doaj +1 more source
Robust Sound Event Classification using Deep Neural Networks [PDF]
, 2015 The automatic recognition of sound events by computers is an important aspect of emerging applications such as automated surveillance, machine hearing and auditory scene understanding.
McLoughlin, Ian Vince +4 more
core +1 more source
Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors
Advanced Science, EarlyView.Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen +8 more
wiley +1 more source
XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss
Advanced Science, EarlyView.Mechanism of GAS‐mediated protection against noise‐induced hearing loss (NIHL). Noise exposure activates the ATF4/eIF2α axis, downregulating XIAP and promoting DDRGK1 degradation, thereby inhibiting ER‐phagy and leading to hair cell (HC) death. GAS treatment rescues XIAP and DDRGK1 expression, reactivating ER‐phagy to mitigate HC loss, synaptic damage,
Lin Yan +13 more
wiley +1 more source
The evolution of auditory contrast [PDF]
, 2009 This paper reconciles the standpoint that language users do not aim at improving their sound systems with the observation that languages seem to improve their sound systems.
Boersma, Paul, Hamann, Silke
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