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Novel insights into mechanisms and therapeutics for presbycusis [PDF]
HeliyonPresbycusis, also referred to as age-related hearing loss, poses a substantial burden on both individuals and society. The hallmark of presbycusis is a progressive decrease in auditory sensitivity.
Guanbin Zhang
exaly +4 more sources
Lancet, The, 2005 The inevitable deterioration in hearing ability that occurs with age--presbycusis--is a multifactorial process that can vary in severity from mild to substantial. Left untreated, presbycusis of a moderate or greater degree affects communication and can contribute to isolation, depression, and, possibly, dementia. These psychological effects are largely
George A Gates, John H Mills
exaly +5 more sources
Presbycusis Across the Lifespan: Genetic, Molecular, and Multi-Omics Contributions [PDF]
Audiology ResearchPresbycusis, or age-related hearing loss (ARHL), is a multifactorial disorder characterized by a gradual, bilateral sensorineural decline in hearing sensitivity, predominantly affecting high-frequency sounds.
Anna Morgan +2 more
doaj +2 more sources
Presbycusis Disrupts Spontaneous Activity Revealed by Resting-State Functional MRI
Frontiers in Behavioral Neuroscience, 2018 Purpose: Presbycusis, age-related hearing loss, is believed to involve neural changes in the central nervous system, which is associated with an increased risk of cognitive impairment.
Xin Dao Yin +2 more
exaly +3 more sources
NeuroImage, 2023 Recent studies suggest that the interaction between presbycusis and cognitive impairment may be partially explained by the cognitive-ear link. However, the underlying neurophysiological mechanisms remain largely unknown.
Fuxin Ren, Steve Hui, Zongrui Dai
exaly +3 more sources
Frontiers in Neuroscience, 2022 Presbycusis and tinnitus are the two most common hearing related pathologies. Although both of these conditions presumably originate in the inner ear, there are several reports concerning their central components.
Josef Syka +2 more
exaly +3 more sources
A genome-wide association study about presbycusis and brain cortical structure: Neuroimaging traits from a Mendelian randomization study [PDF]
Journal of OtologyObjectives The causal association between presbycusis and changes in cerebral cortex structure was evaluated through Mendelian randomization (MR).Methods Presbycusis data, serving as the exposure trait, was analyzed using data from the ninth release of ...
Zhencheng Gao +3 more
doaj +2 more sources
Transcriptomic analysis reveals the function of m6A regulators in aged cochlea [PDF]
Brazilian Journal of OtorhinolaryngologyObjective: Presbycusis is a prevalent health issue among the elderly. Previous studies have shown mechanisms related to this condition, but the underlying mechanisms of presbycusis remain elusive.
Yanbing Lai +6 more
doaj +2 more sources
The Effect of Coenzyme Q10 on Tinnitus Severity and Sleep Quality in Patients with Presbycusis [PDF]
Iranian Journal of OtorhinolaryngologyIntroduction: Tinnitus is one of the symptoms of presbycusis that affects patients' sleep and social life. This study aimed to determine the effect of coenzyme Q10 (CoQ10) on treating tinnitus due to presbycusis.
Rohollah Abbasi +3 more
doaj +2 more sources
The Role of Hearing Aids in Improving Dual‐Task Gait Performance in Older Adults With Presbycusis: A Cognitive and Motor Analysis [PDF]
Brain and BehaviorBackground Cognitive decline is a common challenge faced by older individuals with presbycusis; their performance on dual‐task (DT) activities is generally lower compared to those without hearing loss.
Emre Soylemez +4 more
doaj +2 more sources