Results 41 to 50 of about 7,237 (170)

Association Characteristics and Potential Mechanisms of Aging, Gut Microbiota, and Hearing Loss

Integrative Zoology, EarlyView.
The study found that aging leads to unchanged gut microbiota alpha diversity but an increase in Bacteroidetes and a decrease in Firmicutes at the phylum level, with specific genera, species, and functional pathways co‐associated with aging and hearing loss. Through constructing a microbe‐metabolite network, it revealed the mechanism by which protective
Cheng Cheng, Lu Wang, Runhan Li, Wenkai Lai, Chongkui Sun, Jianguo Cui, Bicheng Zhu, Jiang Zhang   +7 more
wiley   +1 more source

Impact of Interprofessional Simulation on Health Students' Self‐Reported Attitudes Towards Older Adults: A Pre‐Post Questionnaire‐Based Study

European Journal of Dental Education, EarlyView.
ABSTRACT Background Aging simulation may promote the knowledge and skills of healthcare providers and students. We hypothesized that interprofessional simulation related to the care of older adults could influence healthcare students' self‐reported attitudes towards older patients. Materials and Methods Interprofessional role‐play simulations dedicated
Sophie Prissette, Vanessa Bloch, Olivier Bourdon, Sandrine Masseron, Aline Hartmann, Marie‐Violaine Berteretche, Hélène Van Hille, Sophie Leignel, Nejma Batikhy, Teddy Jametal, Adeline Braud   +10 more
wiley   +1 more source

Early Outer Hair Cell Dysfunction Associated With Educational Noise Exposure in Dental Students: Implications for Hearing Conservation in Dental Education

European Journal of Dental Education, EarlyView.
ABSTRACT Introduction Dental education involves continuous exposure to high‐frequency noise from clinical instruments, which may cause early outer hair cell damage even before professional practice begins. While noise‐induced hearing loss (NIHL) is a recognised occupational hazard among dentists, evidence regarding subclinical outer hair cell changes ...
Merve Yelken Kendirci, Mehtap Ungor, Handan Turan Dizdar, Ahmet Faruk Erturk, Ilknur Ozcan   +4 more
wiley   +1 more source

Psychometric properties of the Ekman 60‐Faces Test in clinical populations: A systematic review and meta‐analysis

Journal of Neuropsychology, EarlyView.
Abstract The Ekman 60‐Faces Test is widely used to assess facial emotion recognition, but information on its validity and reliability is scarce. This systematic review evaluated the reporting of psychometric properties across clinical populations. A total of 159 studies (n = 5978) were included: case–control (n = 109), single cohort (n = 37) and review/
Linde Assendelft, Jackie M. Poos, Esther van den Berg   +2 more
wiley   +1 more source

Pitch and Loudness Tinnitus in Individuals with Presbycusis

International Archives of Otorhinolaryngology, 2016
Introduction Tinnitus is a symptom that is often associated with presbycusis. Objective This study aims to analyze the existence of association among hearing thresholds, pitch, and loudness of tinnitus in individuals with presbycusis ...
Bruna Macangnin Seimetz, Adriane Ribeiro Teixeira, Leticia Petersen Schmidt Rosito, Leticia Sousa Flores, Carlos Henrique Pappen, Celso Dall'igna   +5 more
doaj   +1 more source

Connexin 30 deletion exacerbates cochlear senescence and age-related hearing loss

Frontiers in Cell and Developmental Biology, 2022
Pathogenic mutations in the Gjb2 and Gjb6 genes, encoding connexin 26 (Cx26) and connexin 30 (Cx30), respectively, have been linked to the most frequent monogenic hearing impairment, nonsyndromic hearing loss, and deafness DFNB1.
Fabiola Paciello, Fabiola Paciello, Veronica Zorzi, Marcello Raspa, Ferdinando Scavizzi, Claudio Grassi, Claudio Grassi, Fabio Mammano, Fabio Mammano, Anna Rita Fetoni, Anna Rita Fetoni   +10 more
doaj   +1 more source

Herbal Formula AC591 Protects Against Cisplatin‐Induced Hearing Loss by Inhibiting p53‐Mediated Ferroptosis

Smart Medicine, Volume 5, Issue 5, October 2026.
AC591 and its core active component 18β‐glycyrrhetinic acid effectively alleviate cisplatin‐induced ototoxicity by binding p53 and suppressing p53‐mediated ferroptosis, representing promising agents for preventing cisplatin‐related hearing loss. ABSTRACT Cisplatin is a widely utilized chemotherapeutic agent for the treatment of malignant cancers ...
Yunhao Wu, Yu Tao, Lin Wei, Qiuping Liu, Jiaxin Liu, Wen Jiang, Weiwei Shi, Peng Cao, Xiaolong Fu, Cheng Cheng   +9 more
wiley   +1 more source

IGF‐1/SLC25A33 Maintains Blood‐Labyrinth Barrier Integrity by Suppressing TGF‐β/Smad2‐Mediated Pericyte Activation in Age‐Related Hearing Loss

Aging Cell, Volume 25, Issue 10, October 2026.
IGF‐1/SLC25A33–TGF‐β/Smad2 axis can regulate pericyte activation and BLB integrity, which may be a potential therapeutic target for preserving hearing in ARHL. ABSTRACT Age‐related hearing loss (ARHL) is a prevalent sensory disorder in the elderly, yet the molecular mechanisms underlying cochlear aging remain incompletely understood. While insulin‐like
Rui Xu, Jia Tang, Huan Lin, Qi Li, Yajin Feng, Xiaorong Zhang, Xiaohong Hu, Jiacai Yang, Yuhong Li, Yang Bai   +9 more
wiley   +1 more source

Association of genetic variations in the mitochondrial DNA control region with presbycusis

Clinical Interventions in Aging, 2017
Masoumeh Falah,1 Mohammad Farhadi,1 Seyed Kamran Kamrava,1 Saeid Mahmoudian,1 Ahmad Daneshi,1 Maryam Balali,1 Alimohamad Asghari,2 Massoud Houshmand1,3 1ENT and Head & Neck Research Center and Department, Iran University of Medical Sciences, Tehran,
Falah M, Farhadi M, Kamrava SK, Mahmoudian S, Daneshi A, Balali M, Asghari A, Houshmand M   +7 more
doaj  

Aging Alters Hair Cell Physiological Properties in Mice With Late‐Onset Age‐Related Hearing Loss

Aging Cell, Volume 25, Issue 9, September 2026.
Hidden hearing loss during aging is associated with peripheral auditory system decline. We discovered that aging sensory hair cells decrease in size. In addition, inner hair cells exhibit a reduced K+ current carried out by BK channels, accompanied by an elevated resting membrane potential, suggesting an age‐related functional impairment.
Piece Yen, Adam J. Carlton, Andrew O'Connor, Niovi Voulgari, Stuart L. Johnson, Jing‐Yi Jeng   +5 more
wiley   +1 more source