Results 61 to 70 of about 7,237 (170)
PLoS ONE, 2014 Age-related hearing loss - presbycusis - is the number one neurodegenerative disorder and top communication deficit of our aged population. Like many aging disorders of the nervous system, damage from free radicals linked to production of reactive oxygen
Sherif F Tadros +3 more
doaj +1 more source
Aging Cell, Volume 25, Issue 7, July 2026.This study maps age‐aligned cochlear and vestibular decline in SAMP8 mice, linking functional impairment with synaptic vulnerability, mitochondrial ultrastructural injury, and autophagy/mitophagy–lysosome transcriptional remodeling. The findings provide an integrated framework for understanding shared inner‐ear aging trajectories.
Jingyi Xie +14 more
wiley +1 more source
Toward a test battery for differential categorization of age-related hearing loss
Journal of Indian Speech Language & Hearing Association, 2014 Age-related hearing loss (ARHL, or presbycusis) results from neural and/or cochlear degeneration. A taxonomy distinguishing presbycusis subtypes according to site of lesion was originally proposed by linking audiometric results to histopathological ...
Rachael R. Baiduc +2 more
doaj +1 more source
Speech‐In‐Noise Perception in Alzheimer's Disease and Primary Progressive Aphasia
European Journal of Neurology, Volume 33, Issue 7, July 2026.Speech‐in‐noise perception is impaired in Alzheimer's disease and primary progressive aphasia when accounting for peripheral hearing and general cognitive functions, and is associated with grey matter volume in the right supramarginal gyrus. ABSTRACT Background Understanding speech despite background noise is essential for everyday communication, but ...
Sophie A. Froud +10 more
wiley +1 more source
Frontiers in Aging Neuroscience, 2018 Presbycusis (age-related hearing loss) is a potential risk factor for tinnitus and cognitive deterioration, which result in poor life quality. Presbycusis-related tinnitus with cognitive impairment is a common phenotype in the elderly population.
Qingwei Ruan +5 more
doaj +1 more source
Transcriptomic analysis reveals the function of m6A regulators in aged cochlea
Brazilian Journal of OtorhinolaryngologyObjective: Presbycusis is a prevalent health issue among the elderly. Previous studies have shown mechanisms related to this condition, but the underlying mechanisms of presbycusis remain elusive.
Yanbing Lai +6 more
doaj +1 more source
PLoS ONE, 2014 Age-related dysfunction of the central auditory system, also known as central presbycusis, can affect speech perception and sound localization. Understanding the pathogenesis of central presbycusis will help to develop novel approaches to prevent or ...
Lingling Zeng +7 more
doaj +1 more source
Mechanisms of Sensorineural Cell Damage, Death and Survival in the Cochlea
Frontiers in Aging Neuroscience, 2015 The majority of acquired hearing loss, including presbycusis, is caused by irreversible damage to the sensorineural tissues of the cochlea. This article reviews the intracellular mechanisms that contribute to sensorineural damage in the cochlea, as well
Allen Frederic Ryan +4 more
doaj +1 more source
Detecting hazardous situations faced by presbycusic pedestrians in cities: an audio-texture approach
Ambiances, 2015 Within a universal context of an aging population along with an increasing consciousness regarding senior pedestrians’ safe access to the city, we examine the case of seniors affected by presbycusis, specifically their altered perceptions of the urban ...
Faten Hussein +3 more
doaj +1 more source
European Journal of Investigation in Health, Psychology and Education, 2018 Objetivo. Describir el estado de salud auditiva en personas mayores de 64 años autónomas y residentes en un municipio del cinturón industrial de Barcelona, destacando los datos sobre la prevalencia de la Presbiacusia. Participantes.
Jesús Valero-García +1 more
doaj +1 more source