Results 51 to 60 of about 6,864 (169)

Aging and Hearing with Vestibular Schwannoma Beyond Presbycusis: A Large Cross‐Sectional Audiometric and Volumetric Study

OTO Open, Volume 10, Issue 3, July-September 2026.
Abstract Objective To identify predictors of auditory function in treatment‐naïve vestibular schwannomas (VS) while accounting for age‐related hearing loss, investigating baseline volumetrics and audiometrics in a pre‐intervention stereotactic radiosurgery (SRS) cohort. Study Design Cross‐sectional study.
Sami Barrit, Mejdeddine Al Barajraji, Salim El Hadwe, Jérome R. Lechien, Daniele Morelli, Cécile Renier, Nicolas Massager   +6 more
wiley   +1 more source

An animal model for presbycusis [PDF]

The Laryngoscope, 1972
AbstractCochlear microphonics (CM) and masked and unmasked VIIIth nerve action potentials (AP) were measured in rats at ages of one, six, 12, 18 and 24 months in order to explore an animal model for presbycusis. These rats were raised in quiet surroundings and were given no antibiotics.
D E, Crowley, V L, Schramm, R E, Swain, R H, Maisel, E, Rauchbach, S N, Swanson   +5 more
openaire   +2 more sources

Comparative Cochlear–Vestibular Aging Reveals Age‐Aligned Mitochondrial Ultrastructural Burden, Mitophagy–Autophagy Remodeling, Synaptic Uncoupling, and Sensory Functional Decline

Aging Cell, Volume 25, Issue 7, July 2026.
This study maps age‐aligned cochlear and vestibular decline in SAMP8 mice, linking functional impairment with synaptic vulnerability, mitochondrial ultrastructural injury, and autophagy/mitophagy–lysosome transcriptional remodeling. The findings provide an integrated framework for understanding shared inner‐ear aging trajectories.
Jingyi Xie, Xujia Zhang, Jinyi Tian, Yulu Yan, Ke Shi, Yongqi Pan, Yanni Zhang, Zichen Chen, Jianbin Sun, Hui Lv, Jingguo Chen, Xiaoyong Ren, Teru Kamogashira, Xiaotong Zhang, Ying Gao   +14 more
wiley   +1 more source

The potential role for use of mitochondrial DNA copy number as predictive biomarker in presbycusis

Therapeutics and Clinical Risk Management, 2016
Masoumeh Falah,1,2 Massoud Houshmand,3 Mohammad Najafi,2 Maryam Balali,1 Saeid Mahmoudian,1 Alimohamad Asghari,4 Hessamaldin Emamdjomeh,1 Mohammad Farhadi1 1ENT and Head & Neck Research Center and Department, Iran University of Medical Sciences ...
Falah M, Houshmand M, Najafi M, Balali M, Mahmoudian S, Asghari A, Emamdjomeh H, Farhadi M   +7 more
doaj  

Speech‐In‐Noise Perception in Alzheimer's Disease and Primary Progressive Aphasia

European Journal of Neurology, Volume 33, Issue 7, July 2026.
Speech‐in‐noise perception is impaired in Alzheimer's disease and primary progressive aphasia when accounting for peripheral hearing and general cognitive functions, and is associated with grey matter volume in the right supramarginal gyrus. ABSTRACT Background Understanding speech despite background noise is essential for everyday communication, but ...
Sophie A. Froud, Benjamin A. Levett, Jessica Jiang, Lucy B. Core, Nehzat Koohi, Madison Tutton, Tim Green, Doris‐Eva Bamiou, Charles R. Marshall, Chris J. D. Hardy, Jason D. Warren   +10 more
wiley   +1 more source

Voxelwise analysis of the central hearing pathway in senior dogs reveals changes associated with fractional lifespan

Scientific Reports
Presbycusis, or age-related hearing loss, affects both elderly humans and dogs, significantly impairing their social interactions and cognition. In humans, presbycusis involves changes in peripheral and central auditory systems, with central changes ...
Chin-Chieh Yang, Pew-Thian Yap, Ye Wu, Natalia Zidan, Gilad Fefer, Nathan C. Nelson, Margaret E. Gruen, Natasha J. Olby   +7 more
doaj   +1 more source

Functional changes in the human auditory cortex in ageing.

PLoS ONE, 2015
Hearing loss, presbycusis, is one of the most common sensory declines in the ageing population. Presbycusis is characterised by a deterioration in the processing of temporal sound features as well as a decline in speech perception, thus indicating a ...
Oliver Profant, Jaroslav Tintěra, Zuzana Balogová, Ibrahim Ibrahim, Milan Jilek, Josef Syka   +5 more
doaj   +1 more source

Phase Separation Drives Pathological Aggregation in Neurodegenerative Diseases: A 15‐Year Bibliometric Landscape (2009–2024)

Annals of the New York Academy of Sciences, Volume 1561, Issue 1, July 2026.
This 15‐year bibliometric study (2009–2024) characterizes the global landscape of liquid–liquid phase separation (LLPS) in neurodegenerative diseases. We delineate the field's evolution from fundamental biophysics to clinical translation, emphasizing the liquid‐to‐solid transition of proteins like TDP‐43, tau, and α‐synuclein.
Chanyuan Zhang, Siyao Chen, He Zhao, Yan Wang, Lingyan Zhou, Haixia Fan, Yan Sun   +6 more
wiley   +1 more source

CASE REPORT: UNCONTROLLED HYPERTENSION CONTRIBUTES TO WORSENING OF PRESBYCUS SYMPTOMS IN THE ELDERLY

Journal of Community Medicine and Public Health Research, 2020
Presbycusis is a disease that can befall the elderly, caused by a multifactorial process that should be allowed to disrupt communication and social life and cause mental disorders.
Faradila Budi Saputri, Azizah Amimathul Firdha, Safira Rahma, Rieza Rizqy Alda, Syahwina Inayasari, Nyilo Purnami   +5 more
doaj   +1 more source

Magnitude, Patterns and Factors Associated With Sensorineural Hearing Loss Among Hypertensive Adults at a Tertiary Hospital in Northern Tanzania

Eye &ENT Research, Volume 3, Issue 2, Page 101-106, June 2026.
ABSTRACT Background Hearing loss affects 1.5 billion people globally, with sensorineural hearing loss (SNHL) linked to hypertension. Hypertension affects 1.39 billion people worldwide and its prevalence is rising sharply in Sub‐Saharan Africa. While 12% of Tanzanian population has cardiovascular diseases, including hypertension and recent studies ...
Johnson Shayo, Denis Katundu, Abdallah Jonas, Peter Shija   +3 more
wiley   +1 more source