Results 1 to 10 of about 126,431 (255)

The cognitive cost of age-related hearing loss. [PDF]

BMC Geriatr
Background Age-related hearing loss (ARHL) or presbycusis is a bilateral sensorineural hearing impairment associated with aging of the structures of the inner ear and auditory pathways and is the most common cause of acquired hearing loss in older adults.
Crnojević M, Komazec Z, Lemajić-Komazec S, Denda N, Bugarski Ignjatović V.   +4 more
europepmc   +2 more sources

Progress on mechanisms of age-related hearing loss

Frontiers in Neuroscience, 2023
Age-related hearing loss, or presbycusis, is a common cause of hearing loss in elderly people worldwide. It typically presents as progressive, irreversible, and usually affects the high frequencies of hearing, with a tremendous impact on the quality of ...
Wen Yang, Xiaolong Zhao, Renjie Chai, Renjie Chai, Renjie Chai, Jiangang Fan   +5 more
doaj   +3 more sources

Living with age-related hearing loss and insights for hearing care: a qualitative descriptive study. [PDF]

Int J Qual Stud Health Well-being
Objectives Age-related hearing loss is a common chronic condition that affects nearly one-fifth of the global population. It severely impairs communication, leading to social isolation, depression, and reduced quality of life of older adults ...
Jung D, Shin S, Byeon S, Yoo L, Seo H.
europepmc   +2 more sources

Multi-ancestry GWAS of age-related hearing loss identifies 140 loci and key cellular mechanisms. [PDF]

Nat Commun
Age-related hearing loss is a prevalent and growing public health issue among the elderly. Here, we perform a multi-ancestry genome-wide association study comprising 456,613 cases and 1,053,834 controls, identifying 140 independent loci associated with ...
Shi L, He H, Li J, Gai K, Li W, Zhao Y, Yuan H, Wu Y.   +7 more
europepmc   +2 more sources

Superenhancer-mediated ferroptosis in age-related hearing loss: cochlear epigenomics. [PDF]

Cell Mol Life Sci
Background Age-related hearing loss (ARHL), also known as presbycusis, is a prevalent condition among older adults and affects a substantial proportion of the global aging population. The underlying mechanisms of ARHL remain unclear, and this study aimed
Zhang C, Yang T, Luo X, Fu X, Sun Y, Yuan W.   +5 more
europepmc   +2 more sources

Potential therapeutic role of SIRT1 in age- related hearing loss

Frontiers in Molecular Neuroscience, 2022
Age-related hearing loss (ARHL) is a major public health burden worldwide that profoundly affects the daily life of elderly people. Silent information regulator 1 (SIRT1 or Sirtuin1), known as a regulator of the cell cycle, the balance of oxidation ...
Tingting Zhao, Tingting Zhao, Guangyong Tian, Guangyong Tian   +3 more
doaj   +1 more source

Bats experience age-related hearing loss (presbycusis)

Life Science Alliance, 2023
Bats exhibited age-related hearing loss. Bats are exposed to immense conspecific noise, but the frequency-dependent hearing loss was not correlated to the noise.
Yifat Chaya Tarnovsky, Shahar Taiber, Yomiran Nissan, Arjan Boonman, Yaniv Assaf, Gerald S Wilkinson, Karen B Avraham, Yossi Yovel   +7 more
doaj   +1 more source

HEARING HANDICAP IN OLDER ADULTS: A MULTI-CENTER STUDY

Pakistan Armed Forces Medical Journal, 2021
Objective: To determine the level of hearing handicap and its age and gender association in older adults. Study Design: Cross sectional analytical study.
Gul -e- Zahra, Ghulam Saqulain, Nazia Mumtaz   +2 more
doaj   +1 more source

Age-Related Hearing Loss With Tinnitus and Physical Frailty Influence the Overall and Domain-Specific Quality of Life of Chinese Community-Dwelling Older Adults

Frontiers in Medicine, 2021
Objective: To investigate the impact of the severity of age-related hearing loss (ARHL) and tinnitus, presence of ARHL and/or tinnitus, and physical frailty on the health-related quality of life (HRQoL) and domain-specific HRQoL in Chinese community ...
Weibin Zhang, Weibin Zhang, Jian Ruan, Ruxin Zhang, Min Zhang, Min Zhang, Xiuhua Hu, Xiuhua Hu, Zhuowei Yu, Zhuowei Yu, Zhuowei Yu, Zhao Han, Qingwei Ruan, Qingwei Ruan   +13 more
doaj   +1 more source

The influence of metabolic syndrome on age-related hearing loss from the perspective of mitochondrial dysfunction

Frontiers in Aging Neuroscience, 2022
With the increase in life expectancy in the global population, aging societies have emerged in many countries, including China. As a common sensory defect in the elderly population, the prevalence of age-related hearing loss and its influence on society ...
Dongye Guo, Dongye Guo, Dongye Guo, Andi Zhang, Andi Zhang, Andi Zhang, Tianyuan Zou, Tianyuan Zou, Tianyuan Zou, Rui Ding, Rui Ding, Rui Ding, Kaili Chen, Kaili Chen, Kaili Chen, Yi Pan, Yi Pan, Yi Pan, Peilin Ji, Peilin Ji, Peilin Ji, Bin Ye, Bin Ye, Bin Ye, Mingliang Xiang, Mingliang Xiang, Mingliang Xiang   +26 more
doaj   +1 more source