Results 11 to 20 of about 126,431 (255)

Age-related Hearing Impairment and the Triad of Acquired Hearing Loss [PDF]

open access: yesFrontiers in Cellular Neuroscience, 2015
Understanding underlying pathological mechanisms is prerequisite for a sensible design of protective therapies against hearing loss. The triad of age-related, noise-generated, and drug-induced hearing loss ¬¬displays intriguing similarities in some ...
Chao-Hui eYang   +3 more
doaj   +3 more sources

Age-Related Hearing Loss [PDF]

open access: yesCold Spring Harbor Perspectives in Medicine, 2018
Age-related hearing loss (ARHL) is the most prevalent sensory deficit in the elderly. This progressive hearing impairment leads to social isolation and is also associated with comorbidities, such as frailty, falls, and late-onset depression. Moreover, there is a growing evidence linking it with cognitive decline and increased risk of dementia.
Michael R, Bowl, Sally J, Dawson
openaire   +3 more sources

Genetics of age‐related hearing loss [PDF]

open access: yesJournal of Neuroscience Research, 2020
AbstractAge‐related hearing loss (ARHL) has recently been confirmed as a common complex trait, that is, it is heritable with many genetic variants each contributing a small amount of risk, as well as environmental determinants. Historically, attempts to identify the genetic variants underlying the ARHL have been of limited success, relying on the ...
Helena Rose Rees Wells   +2 more
openaire   +3 more sources

Evaluation of Age-Related Hearing Loss [PDF]

open access: yesKorean Journal of Audiology, 2013
Age-related hearing loss (presbycusis) is characterized by an increased hearing threshold and poor speech understanding in a noisy environment, slowed central processing of acoustic information, and impaired localization of sound sources. Presbycusis seriously affects the older people's quality of life.
Kim, Tae Su, Chung, Jong Woo
openaire   +2 more sources

Two Loci Contribute to Age-Related Hearing Loss Resistance in the Japanese Wild-Derived Inbred MSM/Ms Mice

open access: yesBiomedicines, 2022
An MSM/Ms strain was established using Japanese wild mice, which exhibit resistance to several phenotypes associated with aging, such as obesity, inflammation, and tumorigenesis, compared to common inbred mouse strains.
Shumpei P. Yasuda   +13 more
doaj   +1 more source

Development of the General Practitioner Management of Age-related Hearing Loss System [PDF]

open access: yesZhongguo quanke yixue, 2022
Background The prevalence of age-related hearing loss is increasing gradually as population aging advances in China. Untreated hearing loss is strongly associated with many adverse health events.
GE Jianli, GENG Shasha, CHEN Xin, ZHU Yingqian, SUN Xiaoming, JIANG Hua
doaj   +1 more source

Age-related hearing loss accelerates the decline in fast speech comprehension and the decompensation of cortical network connections

open access: yesNeural Regeneration Research, 2023
Patients with age-related hearing loss face hearing difficulties in daily life. The causes of age-related hearing loss are complex and include changes in peripheral hearing, central processing, and cognitive-related abilities. Furthermore, the factors by
He-Mei Huang   +12 more
doaj   +1 more source

Early Health Economic Modeling of Novel Therapeutics in Age-Related Hearing Loss

open access: yesFrontiers in Neuroscience, 2022
BackgroundHealth systems face challenges to accelerate access to innovations that add value and avoid those unlikely to do so. This is very timely to the field of age-related sensorineural hearing loss (ARHL), where a significant unmet market need has ...
Evie C. Landry   +11 more
doaj   +1 more source

The Laterality of Age-related Hearing Loss and Cognition

open access: yesOtology & Neurotology Open, 2022
Objectives: To analyze the association between neurocognitive performance and age-related hearing loss in the right and left ear, individually. Design: Subjects included 5277 participants (≥50 years) from the general Hispanic population who underwent audiometric testing in a US ...
Chern, Alexander   +2 more
openaire   +2 more sources

Prognostic Gene Expression Signature for Age-Related Hearing Loss

open access: yesFrontiers in Medicine, 2022
BackgroundOur study aimed to determine the pathological mechanism of presbycusis at the molecular level, and determine potential biomarkers for the same.MethodsDifferentially expressed genes (DEGs) for presbycusis were obtained by analyzing the ...
Lu Peng   +4 more
doaj   +1 more source

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