Results 11 to 20 of about 121,313 (254)

Age-related Hearing Impairment and the Triad of Acquired Hearing Loss [PDF]

Frontiers in Cellular Neuroscience, 2015
Understanding underlying pathological mechanisms is prerequisite for a sensible design of protective therapies against hearing loss. The triad of age-related, noise-generated, and drug-induced hearing loss ¬¬displays intriguing similarities in some ...
Chao-Hui eYang, Chao-Hui eYang, Thomas eSchrepfer, Jochen eSchacht   +3 more
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Age-Related Hearing Loss [PDF]

Cold Spring Harbor Perspectives in Medicine, 2018
Age-related hearing loss (ARHL) is the most prevalent sensory deficit in the elderly. This progressive hearing impairment leads to social isolation and is also associated with comorbidities, such as frailty, falls, and late-onset depression. Moreover, there is a growing evidence linking it with cognitive decline and increased risk of dementia.
Michael R, Bowl, Sally J, Dawson
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Genetics of age‐related hearing loss [PDF]

Journal of Neuroscience Research, 2020
AbstractAge‐related hearing loss (ARHL) has recently been confirmed as a common complex trait, that is, it is heritable with many genetic variants each contributing a small amount of risk, as well as environmental determinants. Historically, attempts to identify the genetic variants underlying the ARHL have been of limited success, relying on the ...
Helena Rose Rees Wells, Tracey A. Newman, Frances M. K. Williams   +2 more
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Evaluation of Age-Related Hearing Loss [PDF]

Korean Journal of Audiology, 2013
Age-related hearing loss (presbycusis) is characterized by an increased hearing threshold and poor speech understanding in a noisy environment, slowed central processing of acoustic information, and impaired localization of sound sources. Presbycusis seriously affects the older people's quality of life.
Kim, Tae Su, Chung, Jong Woo
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The influence of metabolic syndrome on age-related hearing loss from the perspective of mitochondrial dysfunction

Frontiers in Aging Neuroscience, 2022
With the increase in life expectancy in the global population, aging societies have emerged in many countries, including China. As a common sensory defect in the elderly population, the prevalence of age-related hearing loss and its influence on society ...
Dongye Guo, Dongye Guo, Dongye Guo, Andi Zhang, Andi Zhang, Andi Zhang, Tianyuan Zou, Tianyuan Zou, Tianyuan Zou, Rui Ding, Rui Ding, Rui Ding, Kaili Chen, Kaili Chen, Kaili Chen, Yi Pan, Yi Pan, Yi Pan, Peilin Ji, Peilin Ji, Peilin Ji, Bin Ye, Bin Ye, Bin Ye, Mingliang Xiang, Mingliang Xiang, Mingliang Xiang   +26 more
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Two Loci Contribute to Age-Related Hearing Loss Resistance in the Japanese Wild-Derived Inbred MSM/Ms Mice

Biomedicines, 2022
An MSM/Ms strain was established using Japanese wild mice, which exhibit resistance to several phenotypes associated with aging, such as obesity, inflammation, and tumorigenesis, compared to common inbred mouse strains.
Shumpei P. Yasuda, Yuki Miyasaka, Xuehan Hou, Yo Obara, Hiroshi Shitara, Yuta Seki, Kunie Matsuoka, Ai Takahashi, Eri Wakai, Hiroshi Hibino, Toyoyuki Takada, Toshihiko Shiroishi, Ryo Kominami, Yoshiaki Kikkawa   +13 more
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Development of the General Practitioner Management of Age-related Hearing Loss System [PDF]

Zhongguo quanke yixue, 2022
Background The prevalence of age-related hearing loss is increasing gradually as population aging advances in China. Untreated hearing loss is strongly associated with many adverse health events.
GE Jianli, GENG Shasha, CHEN Xin, ZHU Yingqian, SUN Xiaoming, JIANG Hua
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Age-related hearing loss accelerates the decline in fast speech comprehension and the decompensation of cortical network connections

Neural Regeneration Research, 2023
Patients with age-related hearing loss face hearing difficulties in daily life. The causes of age-related hearing loss are complex and include changes in peripheral hearing, central processing, and cognitive-related abilities. Furthermore, the factors by
He-Mei Huang, Gui-Sheng Chen, Zhong-Yi Liu, Qing-Lin Meng, Jia-Hong Li, Han-Wen Dong, Yu-Chen Chen, Fei Zhao, Xiao-Wu Tang, Jin-Liang Gao, Xi-Ming Chen, Yue-Xin Cai, Yi-Qing Zheng   +12 more
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Early Health Economic Modeling of Novel Therapeutics in Age-Related Hearing Loss

Frontiers in Neuroscience, 2022
BackgroundHealth systems face challenges to accelerate access to innovations that add value and avoid those unlikely to do so. This is very timely to the field of age-related sensorineural hearing loss (ARHL), where a significant unmet market need has ...
Evie C. Landry, Evie C. Landry, Evie C. Landry, Mirre Scholte, Matthew P. Su, Matthew P. Su, Yvette Horstink, Rishi Mandavia, Rishi Mandavia, Maroeska M. Rovers, Anne G. M. Schilder, Anne G. M. Schilder   +11 more
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Age-related Hearing Loss and Dementia

Alzheimer Disease & Associated Disorders, 2019
Dementia is a devastating disease and global health challenge that is highly prevalent worldwide. A growing body of research has shown an independent association between age-related hearing loss (ARHL) and dementia, identifying ARHL as a compelling potential target in preventive strategies for dementia.
Alexander, Chern, Justin S, Golub
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